A5076977800- Sexual Differentiation and Disorders
- Diabetes and associated disorders
- Cardiovascular Function and Risk Factors
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Cardiovascular Health and Disease Prevention
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Disease and Adiposity
- Liver Disease Diagnosis and Treatment
- Obesity, Physical Activity, Diet
- Growth Hormone and Insulin-like Growth Factors
- Diet, Metabolism, and Disease
- Diabetes Management and Research
- Birth, Development, and Health
- Urological Disorders and Treatments
- Adipose Tissue and Metabolism
- Adrenal Hormones and Disorders
- Metabolism and Genetic Disorders
- Pancreatic function and diabetes
- Diet and metabolism studies
- Genetic Syndromes and Imprinting
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- Hormonal Regulation and Hypertension
- Pituitary Gland Disorders and Treatments
- Urologic and reproductive health conditions
Necmettin Erbakan University
2016-2025
Owl Research Institute
2021
Selçuk University
2003-2012
Konya Food and Agriculture University
2011-2012
Konya Eğitim ve Araştırma Hastanesi
2010
Erciyes University
2002-2008
Bozok Universitesi
2008
Kayseri Eğitim ve Araştırma Hastanesi
2007
Simple fasting methods to measure insulin resistance, such as the homeostasis model assessment (HOMA), glucose/insulin ratio (FGIR), and quantitative sensitivity check index (QUICKI) methods, have been widely promoted for adult studies but not evaluated formally among children adolescents. The aim of this study was compare HOMA, FGIR, QUICKI measuring expressed by oral glucose tolerance test (OGTT) results, obese adolescents.Fifty-seven pubertal adolescents (30 girls 27 boys; mean age, 12.04...
Article Use of Metformin in Obese Adolescents with Hyperinsulinemia: A 6-month, Randomized, Double-blind, Placebo-controlled Clinical Trial was published on April 1, 2008 the journal Journal Pediatric Endocrinology and Metabolism (volume 21, issue 4).
Few previous studies have examined the validity of fasting glucose-to-insulin ratio (FGIR), homeostasis model assessment insulin resistance (HOMA-IR) and quantitative insulin-sensitivity check index (QUICKI) in pediatric populations.To compare simple indices calculated from glucose levels with sensitivity (area under response curve [AUCinsulin], [ISI-compositeL) determined by oral tolerance testing (OGTT) obese children.One hundred forty-eight children adolescents (86 girls 62 boys, mean...
Nationwide Study of Turner Syndrome ABS TRACTObjective: syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and genetic background affected girls.This study aimed to systematically investigate key TS in relationship large pediatric Turkish patient population.Methods: Our retrospective included 842 karyotype-proven patients aged 0-18 years who were evaluated 35 different centers Turkey...
To measure products of free radical damage in childhood obesity.Plasma radicals were assayed 24 children with exogenous obesity and non-obese healthy controls. A new colorimetric method was used that measures the generation peroxy (D-Roms), first reaction between oxygen.D-Roms levels higher obese than group (33.3+/-10.1 mg% H2O2 vs 22.8+/-2.8 H2O2; p <0.001). Moreover, D-Roms hyperlipidemia normolipidemia (49.6+/-3.1 27.8+/-3.2 level positively correlated waist-hip ratio, serum total...
Abstract Purpose 17α Hydroxylase/17,20 lyase deficiency (17OHD) is a rare form of congenital adrenal hyperplasia, typically diagnosed in late adolescence with symptoms pubertal delay and hypertension. This study aimed to determine the clinical laboratory characteristics 17OHD cases gather data on disease management. Methods Data from 97 nationwide were analyzed using CEDD-NET web system. Diagnostic, follow-up findings, final heights patients evaluated. Results Mean age at admission was 13.54...
An elevated plasma total homocysteine (tHcy) level has recently been established as an independent risk factor for thrombosis and vascular disease. However, the relationship between hyperhomocysteinemia cardiovascular disease obesity remains controversial. The aim of study was to investigate a possible tHcy levels measures childhood obesity.Forty children adolescents with exogenous 20 non-obese subjects in age-and sex-matched control group were investigated. Fasting samples collected tHcy,...
Obesity and hypertension are associated with structural functional cardiac change in children adults. The aim of the study is to evaluate effect obesity on left ventricular geometric patterns functions assessed by conventional Doppler echocardiography.Four hundred thirty obese children, aged 6-17 years 150 age sex-matched healthy controls, were included study. Left geometry was classified as concentric hypertrophy, eccentric remodeling normal geometry.Concentric hypertrophy group had worst...
Abstract Objective: Children with congenital adrenal hyperplasia are considered to be at an elevated risk for cardiovascular morbidity and mortality. The objective of this study was evaluate the association between periaortic fat thickness cardiometabolic profile in children diagnosed hyperplasia. Method: A total 20 adolescents healthy control subjects were enrolled study. We investigated metabolic anthropometric parameters, comparing these values those group. Periaortic assessed using...
Objective: Type 1 diabetes mellitus (T1DM) is a prevalent chronic disease affecting children, necessitating ongoing care from multidisciplinary clinics. This study aimed to determine the prevalence of thyroid dysfunction in newly diagnosed T1DM patients, investigating long-term function through periodic monitoring. Materials and Methods: A retrospective cohort utilized medical records pediatric patients with T1DM. Extracted data included age at initial diagnosis, presenting clinical...
To evaluate clinical experience of amitraz poisoning in children.In this study, the and laboratory features 14 children are presented compared with previous studies.This study revealed that manifestations by oral dermal routes appeared within 30-150 min, central nervous system (CNS) depression, which is most important sign, improved 6-24 hours other signs 24-72 hours. Unlike findings studies, three severe cases our had reversible mydriasis one them required resuscitation because...
Women with Turner syndrome (TS) have greater carotid artery intima-media thickness (cIMT) known to be a risk factor for atherosclerosis in adults. To determine whether there are factors children TS, we compared cIMT, anthropometric and metabolic parameters between TS healthy controls.Data of XO karyotype (n=24, mean age: 11.6±3.6) were those 10.5±3.6) respect parameters, lipid levels, insulin resistance cIMT which was measured by high resolution B-mode ultrasonography.Mean age values similar...
The aim of our study was to evaluate the associations between vitamin D deficiency, atherosclerosis and metabolic syndrome.Two hundred forty-seven obese children adolescents, 8-16 years age (body mass index>95 p) were included in study. Anthropometric measurements, blood pressure lipid profile, level carotid intima media thickness (c-IMT) measured. MS diagnosed according IDF criteria.The prevalance deficieny adolescent 46.6%. Low levels associated with increased carotis syndrome (p=0.03,...
We aimed to report the characteristics at admission, diagnosis, treatment, and follow-up of cases pediatric hyperprolactinemia in a large multicenter study.We reviewed records 233 hyperprolactinemic patients, under 18 years age, who were followed by different centers. The patients divided as having microadenomas, macroadenomas, drug-induced idiopathic hyperprolactinemia. Complaints their mode treatment (medication and/or surgery) outcomes evaluated detail.The mean age with was 14.5 years,...
The worldwide increase in the prevalence of childhood obesity is reaching epidemic proportions and associated with a dramatic rise cases type 2 diabetes. We determined impaired glucose regulation insulin resistance obese children adolescents.A total 196 [SD score (SDS) body mass index (BMI): 2.17 +/- 0.03], aged 7-18 years, including 86 male subjects, underwent an oral tolerance test (1.75 g glucose/kg weight). used modified WHO criteria adapted for abnormal homeostasis. Homeostasis model...
ABS TRACTObjective: There is an increased risk of cardiovascular morbidity in children and adolescents with classical congenital adrenal hyperplasia (CAH), presumably associated obesity, hypertension, impaired glucose tolerance dyslipidemia.This study was designed to evaluate the metabolic profile a group CAH from perspective risk.Methods: Twenty-five patients 25 healthy controls were included study.Metabolic anthropometric parameters investigated compared these two groups.Results: Subjects...