We describe here the extraction and identification of several classes phenolic compounds from lichens Parmotrema dilatatum (Vain.) Hale, tinctorum (Nyl.) Pseudoparmelia sphaerospora Hale Usnea subcavata (Motyka) determined their anti-tubercular activity. The depsides (atranorin, diffractaic lecanoric acids), depsidones (protocetraric, salazinic, hypostictic norstictic xanthones (lichexanthone secalonic acid), usnic acid, as well seven orsellinic acid esters, five salazinic 8',9'-O-alkyl...

Lichens are an important source of phenolic compounds and have been intensively investigated for their biological pharmacological activities. Lecanoric acid (1), a lichen depside, was isolated from Parmotrema tinctorum specimen treated with alcohols to produce orsellinic (2) orsellinates (3) (9) (2,4-dihydroxy-6-n-methyl benzoates). Free radical scavenging activity methyl (3), ethyl (4), n-propyl (5), n-butyl (6), iso-propyl (7), sec-butyl (8), tert-butyl evaluated using...

The anti-Mycobacterium tuberculosis activity of Campomanesia adamantium fruits extracts were evaluated. Six compounds, identified as flavanones and chalcones quantified by HPLC-DAD-UV. Promising antitubercular was observed with ethyl acetate extract (MIC 62.5 µg/mL) their fractions values ranging from 39 to above 250 µg/mL). better MIC result µg/mL associated two that contain bigger amounts 5,7-dihydroxy-6, 8-di-C-methylflavanone 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone. These...

Five flavanones and three chalcones were isolated from Campomanesia adamantium Berg. (Myrtaceae) leaves. The contents of these compounds determined by HPLC. phenolic also determined. monitoring the antioxidant activity was carried out inhibition peroxidation using linoleic acid system radical-scavenging (DPPH). plants collected 4 distinct cities Mato Grosso do Sul State, Brazil. different samples exhibited a range 4.67-232.35 mg/g 15.62-50.71 7.24-21.19 gallic acid. All extracts showed high...

The essential oils from Campomanesia adamantium (Cambess.) O. Berg leaves, collected in the reproductive (flowering and fruit-bearing) vegetative stages, were characterized by GC-MS (Gas Chromatography-Mass Spectrometry). A total of 95 compounds identified. In stage (flowering) major constituents monoterpenes (limonene, α-pinene β-pinene) while during sesquiterpenes (bicyclogermacrene globulol). oil shows high antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa...

The antimicrobial activity of the hexanic extracts and fractions fruits Campomanesia pubescens (D.C) O. Berg adamantium (Cambess.) were assayed against six microorganisms. C. also investigated in their composition by gas chromatography-mass spectrometry high-performance liquid chromatography with diode array detection. results this study showed presence 34 volatile compounds flavonoids extract 33 adamantium.

Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was to measure biological activity vitro Mycobacterium tuberculosis our results showed moderate extract. On other hand S. aureus, P. aeruginosa, setubal, C. albicans, cerevisiae E. coli revealed that inhibited growth all extracts low values antioxidant activities. were analyzed by...

The present study reveals the pharmacological action of Serjania erecta Radlk. (Family Sapindaceae), an important medicinal plant species used in Brazilian Pantanal against gastric pain. methanolic (Me) and chloroformic (Se) extracts obtained from leaves S. were challenged by a very strong necrotizing agent rodents, absolute ethanol. Se was also confronted with nitric oxide synthase inhibitor (N(G)-nitro-L-arginine methyl ester), capsaicin cation channel transient receptor potential...

Campomanesia adamantium (Cambess.) O. Berg, Myrtaceae, é uma espécie nativa. As folhas são utilizadas na medicina popular. Os extratos hexânico e acetato de etila das mostraram pouca variação sua composição química em diferentes estações do ano associado com o desenvolvimento vegetal, enquanto extrato etanólico mostrou alteração significativa relação à química. Todos os etanólicos alta atividade antioxidante frente ao método DPPH moderada a para β-caroteno/ácido linoléico.

Several applications have been proposed for tyrosinase inhibitors in the pharmaceutical, food bioprocessing, and environmental industries. However, only a few compounds are known to serve as effective inhibitors. This study evaluated tyrosinase-related activity of resorcinol (1), orcinol (2) lecanoric acid (3), derivatives this (4-15). Subjected alcoholysis, depside isolated from lichen Parmotrema tinctorum, produces orsellinic (2,4-dihydroxy-6-methylbenzoic acid) (4) orsellinates...

Five flavanones and three chalcones were isolated from Campomanesia adamantium Berg. (Myrtaceae) leaves. The contents of these compounds determined by HPLC. phenolic also determined. monitoring the antioxidant activity was carried out inhibition peroxidation using linoleic acid system radical-scavenging (DPPH). plants collected 4 distinct cities Mato Grosso do Sul State, Brazil. different samples exhibited a range 4.67-232.35 mg/g 15.62-50.71 7.24-21.19 gallic acid. All extracts showed high...

From the ethanol extract of capitula and scapes Syngonanthus bisulcatus (Koern) Ruhland flavonoids 5-hydroxy-7,4'-dimethoxy-6-C-beta-D-glucopyranosylflavone, isovitexin (5,7,4'-trihydroxy-6-C-beta-D-glucopyranosylflavone), luteolin (5,7,3',4'-tetrahydroxyflavone), lutonarin (5,3',4'-trihydroxy-6-C-7-O-beta-D-glucopyranosylflavone) 5,6,3',4'-tetrahydroxy-7-O-beta-D-glucopyrade were isolated. The structure compounds characterized by spectroscopic methods, mainly 1D 2D NMR experiments, as well...

Leaf fractions of Wilbrandia ebracteata were investigated for anti-ulcerogenic effects in ethanol and indomethacin-induced gastric ulcer assays mice. Protective anti-ulcer detected only the ethanol-induced assay after pre-treatment with MeOH extract, chlorophyll-free, chlorophyll residue, HEX, DCM, aqueous fraction, ethyl acetate (EtOAc) fractions. A potent effect was determined animals EtOAc which fractionated isolation active constituents. Seven flavonoids,...

Bromelia balansae (Family Bromeliaceae) is a medicinal plant commonly used in the central region of Brazil as cough syrup and also eaten roasted. The methanolic extract ripe fruits was analyzed by chromatographic methods spectrometrically. Four glycoside flavonols were isolated: kaempferol-3-O-α-L-rhamnopyranoside (1), kaempferol-3-O-α-L-rhamnopyranosyl-(1-->6)-ß-D-glucopyranoside (2), quercetin-3-O-α-L-rhamnopyranosyl-(1-->6)-ß-d-glucopyranoside (3), kaempferol 3,7-di-O-α-L-rhamnopyranoside...

Extracts of six lichen species collected from Brazil and Antarctica were investigated for their potential toxicity radical-scavenging properties.The composition the extracts was using TLC NMR, leading to identification atranorin (1), along with salazinic (2), barbatic (3), a-alectoronic (4), a-collatolic (5), cryptochlorophaeic (6), caperatic (7), lobaric (8), protolichesterinic (9) acids.All acetone evaluated 2,2′-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging ability subjected Artemia...

Although phenolic compounds produced by lichens have been widely investigated in antitumor assays, only a small number evaluated for mutagenicity and genotoxicity. This study protocetraric, hypostictic, psoromic, salazinic acids their potential genotoxic or antigenotoxic activity against somatic cells of Drosophila melanogaster . These were isolated from the Parmotrema dilatatum, Pseudoparmelia sphaerosphora, Usnea jamaicensis, cetratum , respectively, collected Brazilian Cerrado biome. The...

The new flavonoid glycoside kaempferol-3-O-α→ʟ-rhamnopyranosyl(1→ 2)-O-[α-ʟ-rhamnopyranosyl( 1→6)]-O-β-ᴅ-galactopyranoside-7-O-α-ʟ-rhamnopyranoside was isolated together with (S)-zierin from the leaves of Zollernia ilicifolia (Fabaceae), a medicinal plant used as analgesic and antiulcerogenic effects in Brazilian Tropical Atlantic Rain Forest. structures were established on basis 1 H, 13 C NMR 2D (COSY, HMBC, HMQC), UV, MS IV spectra. infusion qualitatively compared to espinheiras-santas...

Os consumidores estão cada vez mais interessados em consumir produtos saudáveis e de melhor qualidade. A dieta oferecida aos animais pode afetar fortemente a composição da carne. Desta forma, objetivou-se avaliar o efeito dos diferentes níveis concentrado sobre perfil lipídico (carne in natura) teor colesterol natura assada) cortes cárneos borregas. Para isso, vinte quatro borregas com peso médio 23,1 ± 2,1 kg foram confinadas alimentadas (20, 40, 60 80%) por 120 dias. As dietas consistiram...