A5058203973- Curcumin's Biomedical Applications
- Health and Well-being Studies
- Atherosclerosis and Cardiovascular Diseases
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Pelvic floor disorders treatments
- Parasitic infections in humans and animals
- Wound Healing and Treatments
- Parasitic Infections and Diagnostics
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Organizational Leadership and Management Strategies
- Congenital Anomalies and Fetal Surgery
- Lipoproteins and Cardiovascular Health
- Pregnancy and preeclampsia studies
- Natural product bioactivities and synthesis
- Nuclear Receptors and Signaling
- Systemic Lupus Erythematosus Research
- Ophthalmology and Visual Health Research
- Education and Islamic Studies
- Reconstructive Surgery and Microvascular Techniques
- Protein Interaction Studies and Fluorescence Analysis
- Neuroinflammation and Neurodegeneration Mechanisms
- Drug Transport and Resistance Mechanisms
York University
2025
Mashhad University of Medical Sciences
2015-2024
Islamic Azad University, Mashhad
2018-2023
Islamic Azad University, Tehran
2023
Kermanshah University of Technology
2023
UNESCO
2023
University of Kashan
2013-2021
Kurdistan University of Medical Sciences
2020
Shiraz University of Medical Sciences
2011-2017
University of Isfahan
2011-2012
Abstract Introduction Dyslipidemia may be defined as increased levels of serum total cholesterol (TC), low-density lipoprotein (LDL-C), triglycerides (TG), or a decreased high-density (HDL-C) concentration. is an established risk factor for cardiovascular disease (CVD). We aimed to investigate the association dyslipidemia and CVD events among population sample from Mashhad, in northeastern Iran. Material methods This prospective cohort study comprised 8698 men women aged 35–65 years who were...
In this study, we determined the interaction of piperine and calf thymus DNA (ct DNA) in Tris-HCl buffer solution at pH = 6.8 also evaluated binding mechanism through data multi-spectroscopic techniques along with thermal melting viscosity measurements. The outcomes fluorescence quenching confirmed occurrence interactions between ctDNA pointed out role as quencher. addition, K
The interaction of calf thymus DNA (ct DNA) with anastrozole, which is acknowledged as an antineoplastic drug, has been enquired into in the absence and presence histone H1, through means absorbance, fluorescence, circular dichroism spectroscopy, viscosity, thermal melting, molecular modeling techniques. In addition, effects anastrozole on MCF 7 cell line have thoroughly investigated. Fluorescence spectroscopy results indicated that quenching mechanism ct DNA-anastrozole are known static...
Abstract Diabetes is one of the most common chronic diseases worldwide. Systemic inflammation (high‐sensitivity C‐reactive protein (hs‐CRP)) and lipid metabolism disruption (lipoprotein A, LipoPr (a)) play a critical role in developing progressing atherosclerosis acute coronary syndrome diabetic patients. The anti‐oxidant anti‐inflammatory effects curcumin have been emphasized previously. Therefore, we aimed to evaluate impact nano‐curcumin on cardiovascular risk factors type 2 patients with...
The metabolic syndrome (MetS) is associated with a pro-inflammatory milieu that may partially account for its association an increased cardiovascular risk. We aimed to (1) evaluate the serum concentrations of twelve cytokines and growth factors (epidermal factor (EGF), interferon-γ (IFN-γ), IL-1α/-1β/-2/-4/-6/-8/-10, monocyte chemoattractant protein-1 (MCP-1), TNF-α vascular endothelial (VEGF)) in 303 individuals or without MetS; (2) explore their relationship presence MetS. Patients MetS...
Abstract Oral mucositis (OM) is a complication of head and neck cancer (HNC) therapy with negative impact on the quality life. Although definitive treatment has not yet been established, there interest towards use natural compounds owing to their few side effects. Curcumin variety biological pharmacological properties including anticancer anti‐inflammatory Aim The aim this study evaluate effect curcumin in form nanomicelle OM HNC patients receiving radiotherapy. Methods In clinical trial, 32...
Metabolic syndrome (MetS) is one of the most important health hazards. Curcumin extracted from Curcuma longa (turmeric), which can affect components MetS. To increase oral bioavailability curcumin, nano‐micelle curcumin used instead powder. In this randomized, double‐blind, controlled clinical trial, 50 patients with MetS were randomly assigned to two groups receive either 80 mg/day nano‐curcumin ( n = 25) or placebo 25), for 12 weeks anthropometric measurements, blood pressure, and...
The prefrontal cortex is the largest lobe of brain and consequently involved in stroke. There no comprehensive practical pharmacological strategy for ameliorating injury induced by cerebral ischemia. Therefore, we studied neuroprotective properties verapamil (Ver) on mitochondrial dysfunction morphological features apoptosis transient global ischemia/reperfusion (I/R). Ninety-six Wistar rats were allocated into four groups: control, I/R, I/R+Ver (10 mg/kg twice 1 hour prior to ischemia after...
Diabetes mellitus is a highly prevalent metabolic disorder which characterized by impaired glucose tolerance, with relative or absolute insulin deficiency and profound changes in the metabolism of macronutrients. Traditional complementary medicine therapeutic strategies that have both been applied to improving glycemic control. Momordica charantia one plant-based, folk medicines used for We aimed review, effects M. on blood clarification molecular pathways involved. Of compounds derived from...
Breast cancer is the leading cause of worldwide. The high expenses associated with chemotherapy as well its side effects make management breast a daunting challenge. most common overexpressed gene in cyclinD1, which induces cell proliferation. Recent investigations into treatment have revealed that curcumin demonstrates potential anti-cancer properties through different pathways. However, oral bioavailability negligible due to hydrophobic structure. Nanotechnology has been employed overcome...
Abstract Serum high‐sensitivity C‐reactive protein (hs‐CRP) is predictive of coronary artery disease (CAD). The aim this study was to examine the possible association hs‐CRP with presence and severity CAD traditional risk factors. This case‐control carried out on 2,346 individuals from September 2011 May 2013. Of these 1,187 had evidence disease, were subject angiography, remainder healthy controls ( n = 1,159). Characteristics determined using standard laboratory techniques serum Hs‐CRP...
Diabetes mellitus (DM) is a significant public health problem and one of the most challenging medical conditions worldwide. It severe complications that make this disease more intricate. A diabetic wound these complications. Patients with diabetes are at higher risk developing foot ulcers (DFU). Due to ineffectiveness Conventional treatments, growth in limb amputation, morbidity, mortality have been recognized, which indicates need for additional treatment. Mesenchymal stem cells (MSCs) can...