Hassan Mehrad‐Majd

ORCID: 0000-0002-8745-6558
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About
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Research Areas
  • Adipokines, Inflammation, and Metabolic Diseases
  • Atherosclerosis and Cardiovascular Diseases
  • Diet and metabolism studies
  • Cancer-related molecular mechanisms research
  • Systemic Lupus Erythematosus Research
  • Neonatal Health and Biochemistry
  • Renal Diseases and Glomerulopathies
  • Diet, Metabolism, and Disease
  • Peroxisome Proliferator-Activated Receptors
  • interferon and immune responses
  • Circular RNAs in diseases
  • Gut microbiota and health
  • MicroRNA in disease regulation
  • Dialysis and Renal Disease Management
  • Systemic Sclerosis and Related Diseases
  • Cholesterol and Lipid Metabolism
  • COVID-19 Clinical Research Studies
  • Helicobacter pylori-related gastroenterology studies
  • Autoimmune and Inflammatory Disorders Research
  • Lipoproteins and Cardiovascular Health
  • Pneumonia and Respiratory Infections
  • Adolescent and Pediatric Healthcare
  • Social Media in Health Education
  • Retinal Imaging and Analysis
  • Lipid metabolism and disorders

Ghaem Hospital
2020-2025

Mashhad University of Medical Sciences
2017-2025

Texas Christian University
2024

Zahedan University of Medical Sciences
2024

Islamic Azad University, Mashhad
2023

Cancer Research Center
2022

University of Neyshabur
2015

The present study was aimed to evaluate the safety, tolerability, and beneficial effects of a ketogenic diet (KD) on body composition blood parameters survival in patients with breast cancer. In this randomized, controlled trial, 60 locally advanced or metastatic cancer planned chemotherapy, were randomly assigned group receiving KDs (n = 30) control standard for 3 months. Serum biochemical analyzed at baseline, every weeks end each arm. Compliance safety KD also checked weekly. Fasting...

10.1080/01635581.2019.1650942 article EN Nutrition and Cancer 2019-09-09

Background: Warfarin has been the primary anticoagulant medication for a long period. However, its efficacy presents clinical challenges, particularly due to increased risk of bleeding. The introduction NOACs, such as rivaroxaban, revolutionized anticoagulation therapy. Nevertheless, evidence regarding their potential side effects conflicting. This study aimed compare incidence major bleeding between rivaroxaban and warfarin. Methods: cohort was conducted at Ghaem Hospital’s emergency...

10.18502/jimc.v8i2.17702 article EN Journal of Iranian Medical Council 2025-01-30

The metabolic syndrome (MetS) is associated with a pro-inflammatory milieu that may partially account for its association an increased cardiovascular risk. We aimed to (1) evaluate the serum concentrations of twelve cytokines and growth factors (epidermal factor (EGF), interferon-γ (IFN-γ), IL-1α/-1β/-2/-4/-6/-8/-10, monocyte chemoattractant protein-1 (MCP-1), TNF-α vascular endothelial (VEGF)) in 303 individuals or without MetS; (2) explore their relationship presence MetS. Patients MetS...

10.1017/s0007114515001038 article EN British Journal Of Nutrition 2015-05-20

Gentamicin (GEN) is considered as a main aminoglycoside antibiotic medicine. The top therapeutic side effect of GEN nephrotoxicity. current research was proposed to determine the protective thymoquinone (TQ) on GEN-induced acute renal failure (ARF).The rats were divided into 6 groups: sham group, control GEN-treated group and TQ-treated groups. At end period, serum blood urea nitrogen (BUN) creatinine (Cr) measured. kidneys then removed for evaluating malondialdehyde (MDA), reduced...

10.1159/000436975 article EN Pharmacology 2015-01-01

Background/Aims: A growing body of evidence supports an important role inflammatory cytokines in the development and progression Metabolic Syndrome (MetS), which explains, at least part, its relationship with increased cardiovascular-risk. Several studies have reported therapeutic-impact crocus-sativus a preclinical/clinical setting. Here we explored effects crocus-sativus, on serum concentrations twelve subjects MetS randomized control trial. Methods: Forty four adult volunteers, who met...

10.2174/1574884712666170622082737 article EN Current Clinical Pharmacology 2018-02-06

Adropin is a metabolic hormone secreted by the liver, brain, and many peripheral tissues involved in energy homeostasis insulin sensitivity. Some reports have indicated significant decrease serum adropin levels type 2 diabetic patients. However, significance of decline level early detection nephropathy (DN) remains to be clarified. The purpose this study was evaluate patients with diabetes without nephropathy.A total 135 unrelated subjects (including 45 nephropathy, healthy controls) were...

10.1159/000519173 article EN cc-by-nc Kidney & Blood Pressure Research 2021-01-01

Statins are first-line lipid-lowering agents with tolerable adverse reactions, low cost, and high availability worldwide. The potent anti-inflammatory, antioxidant, anti-thrombotic immunomodulatory effects of statins propose them as an option against COVID-19 infection.In this randomized triple-blind placebo-controlled clinical trial, we have investigated the atorvastatin efficacy in management mild to moderate hospitalized patients.In study, 52 patients who fulfilled inclusion criteria were...

10.2174/2772434417666220902153823 article EN Recent Advances in Anti-Infective Drug Discovery 2022-09-03

Background: Kidney involvement is prevalent in systemic lupus erythematosus (SLE) and the leading cause of disability death. Colony-stimulating factor-1 (CSF-1) may be involved development nephritis (LN). This study aimed to evaluate serum CSF-1 levels SLE patients with without proteinuria its correlation value proteinuria. Methods: A total 75 subjects including 25 newly diagnosed cases renal evidence, new biopsy-proven LN, also, healthy controls were included study. Serum level was measured...

10.34172/jkmu.3807 article EN cc-by Majallah-i dānishgāh-i ̒ulum-i pizishkī-i Kirmān. 2025-01-18

The present study aimed to evaluate the endoscopic findings of patients with dyspepsia in Ghaem Hospital, Mashhad, Iran. This cross-sectional collected dyspepsia, including epigastric pain or heartburn, postprandial fullness, and early satiety from Hospital 2019 2020. Totally, 743 were studied, 42.3% (n=314) male. mean age was 46 years. Among participants, 85.6% (n=636) included functional group, rest organic group. In highest frequency related peptic ulcer disease, 7.2% (n=53). Moreover,...

10.34172/mejdd.2025.402 article EN cc-by-nc Middle East Journal of Digestive Diseases 2025-01-31

<title>Abstract</title> Objective: This prospective study aims to compare the diagnostic yield of conventional imaging modalities, including CT scan, bone with <sup>99m</sup>Tc-HYNIC-PSMA-11, in detecting local and distant metastases for initial staging treatment-naïve, intermediate- high-risk prostate cancer (PCa) patients. <sup>68</sup>Ga-PSMA or 18F-PSMA PET/CT scans are known as preferred modalities this kind patients, but there limited facilities developing countries. Methods &amp;...

10.21203/rs.3.rs-5223258/v1 preprint EN Research Square (Research Square) 2025-04-17

ABSTRACT It is debated that probiotics can improve glycolipid metabolism and slow the progression of prediabetes to diabetes mellitus. This study aimed evaluate effect on lipid profile, glucose homeostasis, serum level resistin, adiponectin, vascular endothelial growth factor (VEGF) in prediabetic patients. double‐blind, randomized, placebo‐controlled clinical trial was conducted patients Endocrinology clinic Ghaem Hospital. Patients were randomly divided into two groups: group prescribed a...

10.1002/fsn3.70146 article EN cc-by Food Science & Nutrition 2025-05-01

Abstract Background Otosclerosis is characterized by abnormal bone remodeling in the middle ear, leading to conductive hearing loss. While audiometric findings are valuable diagnosing this condition, Temporal HRCT also plays a helpful role identifying secondary causes and disease. Due conflicting views on diagnostic significance of both procedures, study aimed determine correlation between CT scans patients with otosclerosis. Methods Forty-one referring Otolaryngology departments Ghaem Imam...

10.1186/s43163-025-00817-3 article EN cc-by The Egyptian Journal of Otolaryngology 2025-05-09

ABSTRACT Objective Thyroid Autoantibodies (TgAbs) are associated with autoimmune thyroid disorders and also used in cancer follow‐up to monitor for recurrence of disease. This study aimed explore the potential utility TgAbs as a surrogate tumor marker examine relationship between fluctuations levels disease patients Differentiated Cancer (DTC). Methods cohort was conducted on sample 97 who underwent thyroidectomy differentiated (DTC) years 2017 2021. Following surgery (with or without lymph...

10.1002/cnr2.70191 article EN cc-by Cancer Reports 2025-05-01
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