Carolina Bruno de Sousa

ORCID: 0000-0002-2276-8630
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About
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Research Areas
  • Seaweed-derived Bioactive Compounds
  • Genetic and phenotypic traits in livestock
  • Genetic diversity and population structure
  • Parasite Biology and Host Interactions
  • Algal biology and biofuel production
  • Research on Leishmaniasis Studies
  • Identification and Quantification in Food
  • Parasites and Host Interactions
  • Free Radicals and Antioxidants
  • Plant Toxicity and Pharmacological Properties
  • Genetic Mapping and Diversity in Plants and Animals
  • Phytochemical and Pharmacological Studies
  • Glutathione Transferases and Polymorphisms
  • Cynara cardunculus studies
  • Insect symbiosis and bacterial influences
  • Animal Genetics and Reproduction
  • Agricultural and Food Production Studies
  • Science and Education Research
  • Healthcare Regulation
  • Zoonotic diseases and public health
  • Insect Pest Control Strategies
  • Molecular Biology Techniques and Applications
  • Cholinesterase and Neurodegenerative Diseases
  • Bioactive Compounds and Antitumor Agents
  • Trypanosoma species research and implications

Universidade Nova de Lisboa
2020

University of Algarve
2014-2019

Instituto Politécnico de Santarém
2011

Abstract Bioprospecting for novel microalgal strains is key to improving the feasibility of microalgae-derived biodiesel production. Tetraselmis sp. CTP4 (Chlorophyta, Chlorodendrophyceae) was isolated using fluorescence activated cell sorting (FACS) in order screen lipid-rich microalgae. a robust, euryhaline strain able grow seawater growth medium as well non-sterile urban wastewater. Because its large size (9–22 μm), settles down after six-hour sedimentation step. This leads removal...

10.1038/srep35663 article EN cc-by Scientific Reports 2016-10-21

Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules. Methanol extracts thus prepared freeze-dried biomass screened biological activities. Nannochloris sp. SBL1 Desmochloris SBL3 had highest radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl, best copper iron chelating All potent...

10.3390/md13063531 article EN cc-by Marine Drugs 2015-06-03

The development of novel drugs for the treatment leishmaniases continues to be crucial overcome severe impacts these diseases on human and animal health. Several bioactivities have been described in extracts from macroalgae belonging Cystoseira genus. However, none studies has reported chemical compounds responsible antileishmanial activity observed upon incubation parasite with aforementioned extracts. Thus, this work aimed isolate characterize molecules present a hexane extract baccata...

10.1016/j.exppara.2017.01.002 article EN publisher-specific-oa Experimental Parasitology 2017-01-24

AbstractThe fatty acid (FA) composition of six macroalgae from the Cystoseira genus, namely compressa, humilis, tamariscifolia, nodicaulis, baccata and barbata, was determined. Polyunsaturated acids (PUFA) corresponded to 29–46% total FA detected. C. tamariscifolia nodicaulis stood out for their low PUFA/saturated acid, n-6 PUFA/n-3 PUFA ratios as well favourable unsaturation, atherogenicity thrombogenicity indices, suggesting a high nutritional value with potential applications in...

10.1080/14786419.2014.992343 article EN Natural Product Research 2015-01-02

Marine organisms are a prolific source of drug leads in variety therapeutic areas. In the last few years, biomedical, pharmaceutical and nutraceutical industries have shown growing interest novel compounds from marine organisms, including macroalgae. Cystoseira is genus Phaeophyceae (Fucales) macroalgae known to contain bioactive compounds. Organic extracts (hexane, diethyl ether, ethyl acetate methanol extracts) three species ( C. humilis , tamariscifolia usneoides ) were evaluated for...

10.7717/peerj.1704 article EN cc-by PeerJ 2016-02-16

Cystoseira is a common brown algal genus widely distributed throughout the Atlantic and Mediterranean regions whose taxonomical assignment of specimens often hampered by intra- interspecific morphological variability. In this study, three mitochondrial regions, namely cytochrome oxidase subunit 1 (COI), 23S rDNA (23S), 23S-tRNAVal intergenic spacer (mt-spacer) were used to analyse phylogenetic relationships 22 taxa (n = 93 samples). A total 135 sequences (48 from COI, 43 44 mt-spacer) newly...

10.1371/journal.pone.0210143 article EN cc-by PLoS ONE 2019-01-30

Bioprospection of novel autochthonous strains is key to the successful industrial-scale production microalgal biomass. A Chlorococcum strain was recently isolated from a pond inside industrial facility Allmicroalgae (Leiria, Portugal). Phylogenetic analysis based on 18S ribosomal ribonucleic acid (rRNA) gene sequences suggests that this isolate novel, free-living Oophila amblystomatis strain. However, as our phylogenetic data strongly aforementioned taxon belongs genus Chlorococcum, it here...

10.3390/app10093040 article EN cc-by Applied Sciences 2020-04-27

Summary Brazilian goat breeds are believed to derive mainly from animals brought by Portuguese settlers since the 16th century. We used microsatellite markers in a sample of 436 study genetic variability and differentiation six (PT) (BR) currently recognized two countries. These were also compared with an outgroup represented Alpine (ALP) goats. The effective number alleles allelic richness slightly higher PT than BR breeds. global F ST was nearly 0.11 when considered, mean pairwise about...

10.1111/j.1439-0388.2011.00942.x article EN Journal of Animal Breeding and Genetics 2011-07-12

Portugal and Spain, with six 22 officially recognized caprine breeds, encompass 25 % of the European Union goat census. Many these populations have suffered strong demographic declines because competition exotic breeds phasing-out low income rural activities. In this study, we investigated consequences other processes on genetic diversity, population structure inbreeding levels Iberian Atlantic goats. A sample 975 individuals representing from two small not (Formentera Ajuí goats) ecotypes...

10.1186/s12711-015-0167-8 article EN cc-by Genetics Selection Evolution 2015-11-05

Goats have played a key role as source of nourishment for humans in their expansion all over the world long land and sea trips. This has guaranteed place this species important rapid episode livestock triggered by Columbus' arrival Americas late 1400s. The aims study are to provide comprehensive perspective on genetic diversity American goat populations assess origins evolutionary trajectories. was achieved combining data from autosomal neutral markers obtained more than two thousand samples...

10.1017/s1751731117003627 article EN cc-by-nc-nd animal 2018-01-01

Here is reported the anti Leishmania infantum activity of 48 hexane, CH2Cl2 and MeOH extracts from 16 macroalgae collected on Iberian Coast. Seven hexane Cystoseira baccata, barbata, tamariscifolia, usneoides, Dictyota spiralis Plocamium cartilagineum were active towards promastigotes (IC50 29.8–101.8 μg/mL) inducing strong morphological alterations in parasites. Hexane C. baccata barbata also against intracellular amastigotes 5.1 6.8 μg/mL, respectively). Fatty acids, triacylglycerols,...

10.1080/14786419.2018.1434637 article EN Natural Product Research 2018-02-09

The journal transferred to Wolters Kluwer effective 1 January 2018 and all Articles in Press will be published by the new publisher as a result. This Article has therefore been withdrawn from this platform. Should you have any queries please contact Editor-in-Chief, Prof. Abdulmonem Al-Hayani at haya[email protected]. full Elsevier Policy on Withdrawal can found https://www.elsevier.com/about/our-business/policies/article-withdrawal.

10.1016/j.jmau.2017.07.002 article EN cc-by-nc-nd Journal of Microscopy and Ultrastructure 2017-08-01

Marine organisms are a prolific source of drug leads in variety therapeutic areas. In the last few years, biomedical, pharmaceutical and nutraceutical industries have shown growing interest novel compounds from marine organisms, including macroalgae. Cystoseira is genus Phaeophyceae (Fucales) macroalgae known to contain bioactive compounds. Organic extracts (hexane, diethyl ether, ethyl acetate methanol extracts) three species ( C. humilis , tamariscifolia usneoides ) were evaluated for...

10.7287/peerj.preprints.1527 preprint EN 2015-11-24

Macroalgae biosynthesize a wide range of unique secondary metabolites in order to survive the marine environment [1]. Described as potential rich sources bioactive compounds, seaweeds have been recently screened for antileishmanial activity [2,3]. These works show different activities same species from origins, emphasizing importance algal chemical diversity, extraction method or parasite vitro models used [4]. Thus, choice and use clinical relevant stage Leishmania parasites screening...

10.1055/s-0034-1395073 article EN Planta Medica 2014-10-30

The aims of this study, initiated in January 2002, are the identification sylvatic foci trichinellosis and to assess risk factors associated with maintenance spread zoonosis Portugal. study involves examining wild hosts, specifically carnivores boars Sus scrofa from different regions We examined 189 217 (206 foxes Vulpes vulpes, 3 badgers Meles meles, 7 mongooses Herpestes ichneumon one stone marten Martes foina) Alentejo, Beira Interior Trás-os-Montes Alto Douro, To isolate Trichinella L1...

10.7325/galemys.2004.ne.a17 article EN Galemys Spanish Journal of Mammalogy 2004-12-31

Marine organisms are a prolific source of drug leads in variety therapeutic areas. In the last few years, biomedical, pharmaceutical and nutraceutical industries have shown growing interest novel compounds from marine organisms, including macroalgae. Cystoseira is genus Phaeophyceae (Fucales) macroalgae known to contain bioactive compounds. Organic extracts (hexane, diethyl ether, ethyl acetate methanol extracts) three species ( C. humilis , tamariscifolia usneoides ) were evaluated for...

10.7287/peerj.preprints.1527v1 preprint EN 2015-11-24
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