A5070316319- Topic Modeling
- Chinese history and philosophy
- China's Ethnic Minorities and Relations
- Natural Language Processing Techniques
- Higher Education and Teaching Methods
- Multilingual Education and Policy
- Global Education and Multiculturalism
- Physical Education and Training Studies
- Educational Technology and Pedagogy
- Software Engineering Research
- Alkaloids: synthesis and pharmacology
- Japanese History and Culture
- Diverse Music Education Insights
- Acupuncture Treatment Research Studies
- Natural product bioactivities and synthesis
- Video Analysis and Summarization
- Diverse Aspects of Tourism Research
- Physical Activity and Education Research
- Sustainable Finance and Green Bonds
- Multimodal Machine Learning Applications
- Inertial Sensor and Navigation
- Immune cells in cancer
- Early Childhood Education and Development
- Radical Photochemical Reactions
- Educator Training and Historical Pedagogy
Zhengzhou University
2025
Hubei University
2025
Chinese University of Hong Kong
2024
Wuhan Institute of Technology
2024
Krirk University
2023-2024
Chinese Academy of Sciences
2022-2024
Tianjin Medical University
2013-2024
Second People's Hospital of NanTong
2024
Nantong University
2024
Zhejiang University
2024
Abstract Cell signal networks are orchestrated directly or indirectly by various peptide-mediated protein–protein interactions, which normally weak and transient thus ideal for biological regulation medicinal intervention. Here, we develop a general-purpose method modeling predicting the binding affinities of protein–peptide interactions (PpIs) at structural level. The is hybrid strategy that employs an unsupervised approach to derive layered PpI atom–residue interaction (ulPpI[a-r])...
Single-cell proteomics offers unparalleled insights into cellular diversity and molecular mechanisms, enabling a deeper understanding of complex biological processes at the individual cell level. Here, we develop an integrated sample processing on active-matrix digital microfluidic chip for single-cell (AM-DMF-SCP). Employing AM-DMF-SCP approach data-independent acquisition (DIA), identify average 2258 protein groups in single HeLa cells within 15 min liquid chromatography gradient. We...
The phenolate anion was developed as a new photocatalyst with strong reduction potentials (−3.16 V <italic>vs.</italic> SCE) to of aryl halides radicals through single electron transfer.
Abstract The structural features Kopsia alkaloids, in particular multiple all‐carbon quaternary stereocenters a caged and strained polycyclic skeleton, poses challenges for enantioselective total synthesis. Herein, we reported the first synthesis of (+)‐flavisiamine F. synthetic approach involved room‐temperature Overman rearrangement introducing chiral amine at C21, TMS‐promoted ketal Claisen constructing stereocenter C20, late‐stage visible‐light‐induced photochemical cyclization establishing C7.
Urban areas are at high risk of climate change. The impact extreme weather caused by change on different social groups is drawing increasing concerns. This paper focuses the urban distressed migrant population who marginalized in terms society, economy and region. Social survey methods such as questionnaires, focus groups, case interviews used to collect data. Supported Beijing Work Development Center for Facilitators, a non-governmental work organization, their network branches three...
Alzheimer’s disease (AD) is a progressive degenerative of the nervous system that affects older adults. Its main clinical manifestations include memory loss, cognitive dysfunction, abnormal behaviour, and social dysfunction. Neuroinflammation typical in most neurodegenerative diseases, such as AD. Therefore, suppressing inflammation may improve AD symptoms. This study investigated neuroprotective effects Acanthopanax senticosus saponins (ASS) an model induced by streptozotocin (STZ). Here,...
Abstract Diabetic cardiomyopathy (DbCM) is increasingly prevalent, but intervention targets remain unclear due to the lack of appropriate models and complexity risk factors. Here, this work establishes an in vitro assessment system for DbCM function using cardiomyocytes derived from human pluripotent stem cells engineered heart tissue. This finds high‐fat status complex diabetes factors majorly contributes most cardiomyocyte death contractile dysfunction. Notably, PA induced early...
This study draws on data collected from Chinese language textbooks to investigate the ways in which ethnic minority cultures and languages are represented primary school China. Drawing methods of thematic comparative analysis, we specifically analyse how representation minorities has changed across different periods history. The analysis reveals that is largely limited contributions approach additive multicultural curriculum development. findings show a selective, traditional, stereotypical...
Objective A vicious cycle between circadian disruption and escalating immune responses has been described in diverse inflammatory disease. The current study aimed to explore the role of clock autoimmune thyroiditis (AIT). Methods Thirty AIT patients 30 controls were enrolled biopsied for thyroid tissues. Alterations core genes expression tissues, its association with serum tissue biomarkers assessed. For animal studies, C57BL/6J mice administered porcine thyroglobulin or PBS (as control)...
Bullying behaviors, as exhibited by left-behind children (LBC) in China, occur commonly. Parental supervision and support, well friendship networks, have previously been verified crucial aspects determining the bullying behaviors of LBC. However, evidence interactive effect these vital factors is sparse, puppy love, which inevitable among school-age children, seldom investigated. The current study aimed to examine roles parental support peers love LBC means a moderated mediation model. data...
Based on the 2017 China General Social Survey data, with 5,439 observations as research objects, this paper empirically tests impact of flexible employment workers' wellbeing and introduces labor income mediator social security moderator to explore mechanism action. The empirical results show that: has an inverted U-shaped relationship wellbeing, which indicates that increasing employments' flexibility will first rise then reduce their perceived subjective after reaching peak; plays a...
This study examines teachers' cultural diversity beliefs and culturally relevant practices, the predictors of those practices. A sample 606 primary school teachers from southwest China participated in study. The findings reveal that are not necessarily reflected their teaching practices as they marginally correlated. Regression analyses show more likely to implement if Han majority, older, interact frequently with diverse people, competent speaking three or languages, regularly watch, read,...
In Natural Language Interfaces to Databases systems, the text-to-SQL technique allows users query databases by using natural language questions. Though significant progress in this area has been made recently, most parsers may fall short when they are deployed real systems. One main reason stems from difficulty of fully understanding users' paper, we include human loop and present a novel parser-independent interactive approach (PIIA) that interacts with multi-choice questions can easily...
Urological calculi often cause renal colic, which is characterized by paroxysmal or persistent severe pain in the upper abdomen lumbar region. Development of methods to quickly relieve these symptoms has garnered clinical attention. Wrist-ankle acupuncture a type floating therapy administered at selected points carpal and ankle areas, it good pain-relieving effects. We used wrist-ankle combined with nursing for intervention patients confirm its application safety.To study effect treatment...
A mild approach for the synthesis of benzo[j]phenanthridin-6(5H)-one derivatives from 1,7-enynes and aryldiazonium salts has been successfully developed involving a domino radical relay process enabled by heteroleptic Cu(I)-photosensitizer under visible-light-driven photocatalytic conditions. Mechanistic studies disclosed that oxidative quenching excited state PS 4 with via an SET generated aryl radicals, which could play initiator-terminator dual role within whole process, namely, at...