A5032795984- CAR-T cell therapy research
- Virus-based gene therapy research
- Hip disorders and treatments
- Bone and Joint Diseases
- Orthopaedic implants and arthroplasty
- Vascular Malformations Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Research and Treatments
- Orthopedic Infections and Treatments
- Gastrointestinal Tumor Research and Treatment
- Polysaccharides and Plant Cell Walls
- Silk-based biomaterials and applications
- Fungal and yeast genetics research
- Galectins and Cancer Biology
- Moyamoya disease diagnosis and treatment
- Autophagy in Disease and Therapy
- Viral Infectious Diseases and Gene Expression in Insects
- Traumatic Ocular and Foreign Body Injuries
- Vascular Malformations and Hemangiomas
- Head and Neck Surgical Oncology
- Inflammatory Bowel Disease
- Circular RNAs in diseases
- Genomics and Phylogenetic Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Extracellular vesicles in disease
China Jiliang University
2024
Shanghai Ninth People's Hospital
2014-2024
Shanghai Jiao Tong University
2014-2024
Shanghai Institute of Hematology
2024
Zhejiang Sci-Tech University
2020-2023
The First People's Hospital of Xiaoshan District, Hangzhou
2023
Zhejiang Provincial People's Hospital
2022-2023
Xian Yang Central Hospital
2023
Shaoxing University
2022
Hangzhou Medical College
2022
Abstract Human umbilical cord-derived mesenchymal stem cells (hucMSCs) are a promising tool for damaged tissues repair, especially the kidney. However, their efficacy requires improvement. In order to optimize clinical utility of hucMSCs, we adopted strategy treating hucMSCs with 20 μmol/L resveratrol (Res-hucMSCs), applying it in cisplatin-induced acute kidney injury model. Interestingly, found that Res-hucMSCs exhibited more efficient repairing effect than did hucMSCs. Resveratrol-promoted...
Low-flow orbital or periorbital venous malformation (OVM) is the most common vascular lesion that may produce an appearance defect, visual dysfunction, internal hemorrhage, and thrombosis. Intralesional injection of pingyangmycin as a minimally invasive, gentle intervention have better outcomes in treating low-flow OVMs compared with other currently used methods.To investigate efficacy safety intralesional for treatment OVM.A retrospective, noncomparative, interventional case series was...
During the past few decades, colorectal cancer (CRC) incidence and mortality have significantly increased, CRC has become leading cause of cancer-related death worldwide. Thus, exploring novel effective therapies for is imperative. In this study, we investigated effect oncolytic adenovirus CD55-Smad4 on cell growth. Cell viability assay, animal experiments, flow cytometric analysis, migration, invasion assays, Western blotting were used to detect proliferation, apoptosis, cells. The was...
Objective This study aimed to investigate the damage pattern of stress transfer path (STP) for Japanese Investigation Committee (JIC) classification pre-collapse osteonecrosis femoral head. We provide a specific biomechanical basis treatment decisions each subtype. Methods Five computational models were used in experiment. Different necrotic classifications simulated based on JIC system. Damage patterns STP qualitative assessment and average stresses quantitative analysis. Results The type A...
Subarachnoid hemorrhage (SAH) patients' surgery is performed to prevent extravasation of blood into the subarachnoid space. Cerebral vasospasm (CVS; narrowing cerebral arteries) occurs following SAH and represents a major cause associated mortality morbidity. To improve postsurgery care patients their prognosis, ability predict CVS onset critical. We report long noncoding RNA (lncRNA) signature distinguish with from without CVS. Cerebrospinal fluid (CSF) was obtained (n = 10) 10). lncRNAs...
The purpose of this study was to evaluate the clinical features, surgical treatments, and outcomes pediatric post-traumatic nasolacrimal duct obstructions predictors for outcomes.
Objective To examine the usefulness of shock index (Sl) and adjusted (corrected to temperature) (ASI) in predicting prognosis patients with return spontaneous circulation after cardiac arrest.Methods A prospective study,which data such as vital signs cases were collected by Utstein template,was conducted 111 arrest assess value SI ASI for their prognoses.Results There was no evidence show difference between survival hospital discharge ones who died about systolic blood pressure heart rate (P...
Abstract The use of oncolytic viruses as a gene therapy vector is an area active biomedical research, particularly in the context cancer treatment. However, actual therapeutic success this approach to tumor elimination remains limited. As such, present study was developed with goal simultaneously enhancing antitumor efficacy and local immune response by combining Ad-GD55 adenovirus antibody specific for TIM-3 checkpoint molecule (α-TIM-3). resultant Ad-GD55-α-Tim-3 capable inducing α-TIM-3...
Objective To investigate the serum levels of dickkopf-related protein 1 (DKK1) and sclerostin (SOST) in patients with axial spondyloarthritis treated selective cyclo-oxygenase 2 inhibitor its relation to clinical efficacy. Methods A randomized double-blind controlled trial spondyloar-thritis (ax-SpA) was carried out our hospital. The data from a single center collected analyzed. Serum DKK1 SOST were measured by enzyme-linked immuno sorbent assay (ELISA) method before after 12 weeks...