A5025286626- Escherichia coli research studies
- MicroRNA in disease regulation
- Antibiotic Resistance in Bacteria
- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- Salmonella and Campylobacter epidemiology
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Animal Virus Infections Studies
- Plant Gene Expression Analysis
- Virus-based gene therapy research
- Bacterial Genetics and Biotechnology
- Plant biochemistry and biosynthesis
- Cell Adhesion Molecules Research
- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- Bacteriophages and microbial interactions
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Circular RNAs in diseases
- Aquaculture disease management and microbiota
- Advanced biosensing and bioanalysis techniques
- Genomics, phytochemicals, and oxidative stress
- ATP Synthase and ATPases Research
Soochow University
2021-2024
The Fifth People’s Hospital of Suzhou
2020-2024
Wenzhou Medical University
2024
Animal Science Research Institute
2020-2023
Anhui Academy of Agricultural Sciences
2020-2023
Poultry Research Institute
2022
First Hospital of China Medical University
2022
Second Affiliated Hospital of Nantong University
2021
Anhui Agricultural University
2019-2021
Central Hospital of Zibo
2020-2021
Summary The red coloration of pear ( Pyrus pyrifolia ) results from anthocyanin accumulation in the fruit peel. Light is required for biosynthesis pear. A homolog Arabidopsis thaliana BBX 22 , Pp 16 was differentially expressed after fruits were removed bags and may be involved biosynthesis. Here, expression function analysed. 's highly induced by white‐light irradiation, as accumulation. ectopic increased hypocotyls tops flower stalks. localized nucleus showed trans‐activity yeast cells....
Light is indispensable for the accumulation of anthocyanin in peel red pear fruit (Pyrus pyrifolia Nakai). ELONGATED HYPOCOTYL 5 (HY5) considered to be a critical regulator induction biosynthesis, but detailed characterization its regulatory mechanism needed. In this study, multiple genetic and biochemical approaches were applied identify roles P. HY5 (PpHY5) two B-box (BBX) proteins, PpBBX18 PpBBX21, transcriptional regulation PpMYB10. The functions BBX proteins analyzed overexpression...
Summary Flavonoid accumulation in most fruits is enhanced by ethylene and jasmonate. However, little known about the hormone functions related to red pear fruit coloration or their combined effects potential underlying mechanisms. Various treatments were used investigate flavonoid metabolite profile transcriptome verify of jasmonate on biosynthesis as well mechanism behind this. Ethylene inhibits anthocyanin Chinese fruits, whereas increases flavone/isoflavone biosyntheses. The branching...
The administration of cisplatin is limited due to its nephrotoxic side effects, and prevention this nephrotoxicity difficult. Mesenchymal stem cell (MSC)-derived exosomes have been implicated as a novel therapeutic approach for tissue injury. In study, we demonstrated that the pretreatment human umbilical cord MSC-derived (hucMSC-Ex) can prevent development cisplatin-induced renal toxicity by activation autophagy in vitro vivo. vitro, rat tubular epithelial (NRK-52E) cells were pre-incubated...
Light is indispensable for the anthocyanin accumulation of red pear (Pyrus pyrifolia). Anthocyanin biosynthesis catalyzed by a series enzymes encoded structural genes, which are regulated MYB-basic/helix-loop-helix-WD repeat (MYB-bHLH-WDR [MBW]) complex. The bHLH proteins subgroup (SG) IIIf believed to be involved in regulation accumulation. In this study, we revealed that PpbHLH64, belongs SGIIIb, positively regulates and light at transcriptional posttranslational levels. Specifically, an...
Emerging evidence indicates that inappropriate cell-cell fusion might contribute to cancer progression. Similarly, mesenchymal stem cells (MSCs) can also fuse with other spontaneously and capable of adopting the phenotype cells. The aim our study was investigate role MSCs participated cell in tumorigenesis gastric cancer. We fused human umbilical cord (hucMSCs) vitro by polyethylene glycol (PEG), hybrid were sorted flow cytometer. growth migration hybrids assessed counting、cell colony...
Abstract Human umbilical cord-derived mesenchymal stem cells (hucMSCs) are a promising tool for damaged tissues repair, especially the kidney. However, their efficacy requires improvement. In order to optimize clinical utility of hucMSCs, we adopted strategy treating hucMSCs with 20 μmol/L resveratrol (Res-hucMSCs), applying it in cisplatin-induced acute kidney injury model. Interestingly, found that Res-hucMSCs exhibited more efficient repairing effect than did hucMSCs. Resveratrol-promoted...
Salmonella is one of the most important zoonotic pathogens that can cause both acute and chronic illnesses in poultry flocks, also be transmitted to humans from infected poultry. The purpose this study was investigate prevalence, antimicrobial resistance, molecular characteristics isolated diseased clinically healthy chickens Anhui, China. In total, 108 isolates (5.66%) were successfully recovered chicken samples (n = 1908), including pathological tissue (57/408, 13.97%) cloacal swabs...
Abstract The role of mesenchymal stem cells (MSCs) in kidney injury repair has been studied widely. However, the underlying molecular mechanism remains unclear. We profiled altered microRNAs renal tissues from cisplatin-induced acute (AKI) rats treated with or without rat bone marrow MSCs (rMSCs). observed that microRNA-146b (miR-146b) expression was considerably upregulated AKI compared healthy rats, and decreased following MSC treatment after cisplatin administration. At early stage AKI,...
Lipopolysaccharide (LPS)-induced inflammation is the leading cause of multiple organ failure in sepsis. Pyruvate kinase 2 (PKM2) a protein and transcriptional coactivator that plays an important role glycolysis. Recent studies have confirmed glycolysis maintains M1 differentiation induces immune activation macrophages. Lycium barbarum polysaccharide (LBP), main bioactive component Chinese wolfberry, suppresses inflammation. Here, RAW264.7 macrophages were treated with LBP for evaluating its...
Coriolus versicolor (C. versicolor) is a higher fungi or mushroom which now known by its accepted scientific names as Trametes (L.) Lloyd. Many studies have shown that β-glucans from C. various physiological activities, including activating macrophages to protect against Salmonella infection. However, whether antiviral effects has not been reported. Hence, the objective of this study was confirm could boost immune response combat influenza virus in mouse and chick models. The results show...
First identified as a new circovirus in Hunan Province China 2019, porcine (PCV4) is now widely detected other Chinese provinces and South Korea. In recent years, the virus has threatened pig health operations industry. Hence, early PCV4 detection regular surveillance are required to control spread of infection prevent collateral damage Due being difficult isolate vitro, molecular methods, such conventional PCR real-time PCR, serological assays currently main methods used for infection....