A5027184190- Forensic and Genetic Research
- Genetic Associations and Epidemiology
- Molecular Biology Techniques and Applications
- Genetic Mapping and Diversity in Plants and Animals
- Gene expression and cancer classification
- Reservoir Engineering and Simulation Methods
- Forensic Anthropology and Bioarchaeology Studies
- Genetic diversity and population structure
- Bayesian Modeling and Causal Inference
- RNA and protein synthesis mechanisms
- Hydraulic Fracturing and Reservoir Analysis
- Identification and Quantification in Food
- Genetic and phenotypic traits in livestock
- Race, Genetics, and Society
- Geological Modeling and Analysis
- Genomics and Phylogenetic Studies
- Fungal and yeast genetics research
- Autopsy Techniques and Outcomes
- Chronic Kidney Disease and Diabetes
- Horticultural and Viticultural Research
- Enhanced Oil Recovery Techniques
- Fermentation and Sensory Analysis
- Genomics and Chromatin Dynamics
- Neural Networks and Applications
- Geochemistry and Geologic Mapping
Chalmers University of Technology
2012-2024
University of Gothenburg
2011-2024
Linköping University
2014
Norwegian University of Life Sciences
2014
University of Oslo
2007
Norwegian Computing Center
1997-2003
Abstract Background: An abnormal IgLκ:IgLλ ratio has long been used as a clinical criterion for non-Hodgkin B-cell lymphomas. As first step toward quantitative real-time PCR-based multimarker diagnostic analysis of lymphomas, we have developed method determination in samples. Methods: Light-up probe-based PCR was to quantify IgLκ and IgLλ cDNA from 32 The samples were also investigated by routine immunohistochemical flow cytometry. Results: Of suspected lymphoma analyzed, 28 correctly...
Eukaryotic membrane proteins cannot be produced in a reliable manner for structural analysis. Consequently, researchers still rely on trial-and-error approaches, which most often yield insufficient amounts. This means that protein production is recognized by biologists as the primary bottleneck contemporary genomics programs. Here, we describe study to examine reasons successes and failures recombinant yeast, at level of host cell, systematically quantifying cultures high-performance...
Pedigree inference, for example determining whether two persons are second cousins or unrelated, can be done by comparing their genotypes at a selection of genetic markers. When the data one more is from low-coverage next generation sequencing (lcNGS), currently available computational methods either ignore linkage do not take advantage probabilistic nature lcNGS data, relying instead on first estimating genotype. We provide method and software (see familias.name/lcNGS) bridging above gap....
The expression of gene batteries, genomic units functionally linked genes which are activated by similar sets cis- and trans-acting regulators, has been proposed as a major determinant cell specialization in metazoans. We developed predictive procedure to screen the mouse human genomes transcriptomes for cases gene-battery-like regulation. In that covered ~40 per cent all annotated protein-coding genes, we identified 21 co-expressed clusters with statistically supported sharing...
During 2014–2015, Sweden received asylum applications from more than 240,000 people, of which 40,000 were termed unaccompanied minors. In a large number cases, claims by seekers being below 18 years not trusted Swedish authorities. To handle the situation, national board forensic medicine (Rättsmedicinalverket, RMV) was assigned government to create centralized system for medical age assessments. RMV introduced procedure including two biological indicators; x-ray third molars and magnetic...
Genes that are expressed in the same subset of cells potentially constitute a module regulated by shared cis -regulatory elements and distinct set transcription factors. Identifying such units is an important entry point to molecular study cell differentiation. We developed general method classify type-specific genes from sequence tag (EST) data, we optimized it for identification smooth muscle (SMC)-specific genes. Expression profiles were derived quantitative distribution EST data mouse,...
Abstract Background We previously described the first respiratory Saccharomyces cerevisiae strain, KOY.TM6*P, by integrating gene encoding a chimeric hexose transporter, Tm6*, into genome of an hxt null yeast. Subsequently we transferred this phenotype in presence up to 50 g/L glucose yeast V5 hxt1-7 Δ, which only HXT1-7 had been deleted. In study, compared transcriptome resultant V5.TM6*P, with that its wild-type parent, V5, at different concentrations. Results cDNA array analyses revealed...