Giovanna Orsini

ORCID: 0000-0002-2641-0695
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About
Contact & Profiles
Research Areas
  • Dental materials and restorations
  • Dental Implant Techniques and Outcomes
  • Periodontal Regeneration and Treatments
  • Dental Erosion and Treatment
  • Bone Tissue Engineering Materials
  • Endodontics and Root Canal Treatments
  • Oral microbiology and periodontitis research
  • Bone and Dental Protein Studies
  • Oral and Maxillofacial Pathology
  • Mesenchymal stem cell research
  • Bone Tumor Diagnosis and Treatments
  • dental development and anomalies
  • Dental Health and Care Utilization
  • Dental Radiography and Imaging
  • Dental Research and COVID-19
  • Dental Anxiety and Anesthesia Techniques
  • Orthodontics and Dentofacial Orthopedics
  • Dental Trauma and Treatments
  • Oral and gingival health research
  • Protease and Inhibitor Mechanisms
  • Temporomandibular Joint Disorders
  • Orthopaedic implants and arthroplasty
  • Tissue Engineering and Regenerative Medicine
  • Proteoglycans and glycosaminoglycans research
  • RNA and protein synthesis mechanisms

Marche Polytechnic University
2016-2025

University of Zurich
2015-2019

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2016

Ospedali Riuniti di Ancona
2001-2014

Lucky Technology (China)
2013

University of Pisa
2013

University of Chieti-Pescara
2000-2008

University of L'Aquila
2001-2008

Ospedale SS. Annunziata
2006

Giesecke and Devrient (Germany)
2006

Objective: Rehabilitation of the edentulous posterior maxilla with dental implants can be difficult because insufficient bone volume caused by pneumatization maxillary sinus and crestal resorption. Different biomaterials have been used for augmentation. The aim study was to compare different materials in augmentation man. Methods: A total 94 patients participated this study. Inclusion criteria were partial (unilateral or bilateral) edentulism involving premolar/molar areas, presence 3–5-mm...

10.1097/01.id.0000220120.54308.f3 article EN Implant Dentistry 2006-06-01

Abstract Matrix metalloproteinases (MMPs) are a family of peptidases trapped within mineralized dentin matrix and involved with degradation the extracellular components in hybrid layers caries. Despite their identification through indirect evidences biochemical assays, MMP‐2 ‐9 have not been localized human organic matrix. Thus, this study aimed to assess localization distribution by employing correlative field emission in‐lens‐scanning electron microscopy (FEI‐SEM) transmission (TEM)...

10.1002/jbm.a.31920 article EN Journal of Biomedical Materials Research Part A 2008-03-11

The developments in the technologies based on use of autologous adipose tissue attracted attention to minor depots as possible sampling areas. Some those have never been studied detail. present study was performed subcutaneous sampled different areas with aim explaining their morphology, particularly far regards stem niches. results demonstrated that three types white (WAT) can be differentiated basis structural and ultrastructural features: deposit WAT (dWAT), (sWAT) fibrous (fWAT). dWAT...

10.4081/ejh.2010.e48 article EN cc-by-nc European Journal of Histochemistry 2010-11-25

Consumption of acidic foods and drinks other factors that cause enamel wear are responsible for the daily loss degradation. In order to contrast these effects, some toothpastes have been showed possess different properties remineralisation and/or repair surface. Aim this study was evaluate whether use toothpaste containing Zn-carbonate hydroxyapatite (CHA) nanostructured microcrystals may exert remineralisation/repair effects Two groups patients, aged between 18 75 years, used 8 weeks a...

10.3389/fphys.2014.00333 article EN cc-by Frontiers in Physiology 2014-09-05

Background: Placement of dental implants in the posterior maxilla has been associated with higher rates failure that are due, part, to poor bone quality this region. The purpose present study was histologic and histomorphometric evaluation around a new implant surface treatment created by deposition nanometer‐sized calcium phosphate particles added dual acid‐etched surface. Methods: One custom‐made 2 × 10‐mm site (SEI) novel (test) one SEI without (control) were placed 15 patients. All SEIs...

10.1902/jop.2007.060297 article EN Journal of Periodontology 2007-02-01

The refolding and reoxidation of fully reduced denatured chymotrypsinogen A have been studied in the presence low concentrations guanidine HCl or urea. Renaturation yields 60 to 70% were observed when was facilitated by mixtures oxidized glutathione. Refolding occurred within a narrow range denaturant concentration (1.0 1.3 M 2 urea) which native protein shown be stable, regain correct disulfide pairing. Renatured is indistinguishable from zymogen chromatographic behavior, potential...

10.1016/s0021-9258(17)34821-4 article EN cc-by Journal of Biological Chemistry 1978-05-01

Abstract Biological interactions occurring at the bone–biomaterial interface are critical for long‐term clinical success. Bio‐Oss® is a deproteinized, sterilized bovine bone that has been extensively used in regeneration procedures. The aim of present study was comparative light, scanning, and electron microscopy evaluation between specimens retrieved after sinus augmentation Under light microscopy, most particles were surrounded by newly formed bone, while few cases, some it possible to...

10.1002/jbm.b.30196 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2005-05-11

Background: The purpose of the present study was histologic and ultrastructural evaluation a biomaterial composed cortical pig bone in form granules. Methods: After maxillary sinus augmentation using this biomaterial, 10 specimens were retrieved after 5 months patients biomaterial. processed to be observed under light microscopy (LM) transmission electron (TEM). Histomorphometric measurements presented by means ± standard deviations. Results: LM showed that most particles surrounded newly...

10.1902/jop.2006.060181 article EN Journal of Periodontology 2006-11-30

Orsini G, Procaccini M, Manzoli L, Giuliodori F, Lorenzini A, Putignano A. A double‐blind randomized‐controlled trial comparing the desensitizing efficacy of a new dentifrice containing carbonate/hydroxyapatite nanocrystals and sodium fluoride/potassium nitrate dentifrice. J Clin Periodontol 2010; 37: 510–517. doi: 10.1111/j.1600‐051X.2010.01558.x. Abstract Background Aim: Several dentifrices have shown to be effective in reducing dentine hypersensitivity (DH), but more products are needed....

10.1111/j.1600-051x.2010.01558.x article EN Journal Of Clinical Periodontology 2010-05-14

Abstract Human teeth contain a variety of mesenchymal stem cell populations that could be used for cell-based regenerative therapies. However, the isolation and potential use these cells in clinics require extraction functional teeth, process may represent significant barrier to such treatments. Fibroblasts are highly accessible might viable alternative dental cells. We thus investigated compared vitro differentiation human pulp (hDPSCs), gingival fibroblasts (hGFs) foreskin (hFFs). These...

10.1038/s41598-018-37981-x article EN cc-by Scientific Reports 2019-02-11

Dental remineralization represents the process of depositing calcium and phosphate ions into crystal voids in demineralized enamel, producing net mineral gain preventing early enamel lesions progression. The aim present study was to qualitatively quantitatively compare remineralizing effectiveness four commercially available agents on artificial using Scanning Electron Microscopy (SEM) combined with Energy Dispersive Spectroscopy (EDS) techniques. Thirty-six extracted third molars were...

10.3390/ma15134398 article EN Materials 2022-06-22

IntroductionPulp stones (PS) are mineralized ectopic structures within the dental pulp that vary in morphology, composition, and location. Their etiology remains uncertain poses clinical challenges endodontics. This study hypothesized combined analytical techniques would enhance understanding of PS morphology facilitating improved management complex cases.MethodsFifteen permanent molars with radiographic evidence were analyzed using microcomputed tomography (μ-CT), light microscopy scanning...

10.1016/j.joen.2025.02.014 article EN cc-by Journal of Endodontics 2025-03-01

Abstract Calcium sulfate (CaS) has been shown to be a reasonable alternative autogenous bone graft for treating lesions in dentistry. The aim of this work was an histological study the healing defects treated with calcium form cement or beads, animal. Eight New Zealand rabbits, weighing about 2.5 Kg were used study. In each rabbit, four 6 mm created tibial metaphysis. 2 right tibia filled as cement, while left one beads. Four rabbits killed after respectively and 4 weeks, intravenous...

10.1002/jbm.b.20012 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2003-12-16

Autologous bone is the preferred graft material because it carries proteins as bone-enhancing substrates, minerals, and vital cells. Calcium sulfate (CS) a well-tolerated, biodegradable, osteoconductive substitute reasonable alternative to autogenous graft. Blood vessels are an important component of formation maintenance. The process vascular induction called angiogenesis, plays key role in all regenerative processes. Bone tissue differentiation related local presence blood vessels. One...

10.1563/1548-1336(2002)028<0273:brwcse>2.3.co;2 article EN Journal of Oral Implantology 2002-12-01
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