- Advanced Glycation End Products research
- Pancreatic and Hepatic Oncology Research
- Estrogen and related hormone effects
- Liver Disease Diagnosis and Treatment
- Natural Antidiabetic Agents Studies
- Metabolism, Diabetes, and Cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Helicobacter pylori-related gastroenterology studies
- Gallbladder and Bile Duct Disorders
- Diet, Metabolism, and Disease
- Cancer-related molecular mechanisms research
- Radiomics and Machine Learning in Medical Imaging
- Forensic Anthropology and Bioarchaeology Studies
- Biliary and Gastrointestinal Fistulas
- Macrophage Migration Inhibitory Factor
- ATP Synthase and ATPases Research
- Cardiovascular and Diving-Related Complications
- Immune cells in cancer
- Toxin Mechanisms and Immunotoxins
- Phytoestrogen effects and research
- Gastrointestinal disorders and treatments
- Diet and metabolism studies
- Circular RNAs in diseases
- Medical and Biological Sciences
- Esophageal Cancer Research and Treatment
Hospital Regional de Talca
2022-2025
University of Concepción
2023-2024
Hospital Regional de Concepción
2024
Catholic University of the Maule
2020-2023
University of Bologna
2021
University of Chile
2021
Jackson and Tull (United States)
2021
Creative Research Enterprises (United States)
2021
Universidade da Coruña
2021
Johannes Gutenberg University Mainz
2004
In 1992, a transcendental report suggested that the receptor of advanced glycation end-products (RAGE) functions as cell surface for wide and diverse group compounds, commonly referred to (AGEs), resulting from non-enzymatic lipids proteins in response hyperglycemia. The interaction these compounds with RAGE represents an essential element triggering cellular or become glycated. Although initially demonstrated diabetes complications, growing body evidence clearly supports RAGE’s role human...
Type 2 diabetes mellitus (T2DM) is recognized as a serious public health concern with considerable impact on human life, long-term expenditures, and substantial losses. In this context, the use of dietary polyphenols to prevent manage T2DM widely documented. These compounds exert their beneficial effects through several actions, including protection pancreatic islet β-cell, antioxidant capacities these molecules, insulin secretion regulation intestinal microbiota, contribution ameliorate...
A novel nomogram model to predict the prognosis of hepatocellular carcinoma (HCC) treated with radiofrequency ablation and transarterial chemoembolization was recently published in World Journal Gastrointestinal Surgery . This includes clinical laboratory factors, but emerging imaging aspects, particularly from magnetic resonance (MRI) radiomics, could enhance predictive accuracy thereof. Multiparametric MRI deep learning radiomics models significantly improve prognostic predictions for...
Type-2 diabetes mellitus is recognized as a serious public health concern with considerable impact on human life, long-term expenditures, and substantial losses.
 In this context, the use of dietary polyphenols to prevent manage Type 2 widely documented. These compounds exert their beneficial effects by several actions, including protection pancreatic islet β-cell, antioxidant capacities these molecules, insulin secretion regulation intestinal microbiota, contribution ameliorating...
ABSTRACT BACKGROUND: Hydatid disease, a parasitic infestation caused by Echinococcus granulosus larvae, is an infectious disease endemic in different areas, such as India, Australia, and South America. The liver well known the organ most commonly affected hydatid may present wide variety of complications hepatothoracic transit, cyst superinfection, intra-abdominal dissemination, communication biliary with extravasation material into bile duct, also called cholangiohydatidosis. Humans are...
Diagnosing early-stage pancreatic cancer (PC) remains a clinical challenge. Hence, studying novel imaging aspects that could enhance the diagnostic accuracy of malignant precursor lesions is imperative. This article aims to underscore promising role emerging may facilitate earlier diagnosis PC, thereby improving its management and prognosis.
Radiological studies play a crucial role in the evaluation of patients with biliary duct obstruction, allowing for guidance clinical diagnosis towards malignant or stone-induced etiology through recognition relevant imaging features, which must be continuously revisited given their prognostic significance. This article aims to emphasize importance recognizing aspects and obstruction.
Fractures of the lateral process talus (FLPT) are uncommon fractures that represent a clinical challenge. Traditional radiological classification systems rely predominantly on radiographic findings. However, due to high rate FLPT misdiagnosis and limited accuracy in evaluating concomitant talar injuries through plain radiographs, novel imaging have been developed aim enhance diagnosis injuries, thereby optimizing patient management reducing incidence long-term complications.
La dehiscencia timpánica o Foramen de Huschke (FH) se considera un rasgo craneal morfológico menor, hipostósico, no estocástico, transitorio, ubicado en laplaca del hueso temporal, cuya expresión fisiológica hasta los 5 años edad, denominándose como persistente su presencia a mayor edad. mención este la literatura anatómica presenta manera escasa, debido una muy baja poblaciones modernas, situación que cambia al estudiar arqueológicas. El propósito estudio es describir foramen...
e11071 Background: The receptors for estrogen (ESR1) and progesterone (PGR) are widely used risk stratification of breast cancer (BC). corresponding proteins routinely determined by immunohistochemistry (IHC) to categorize tumors into ESR1|PGR groups (+|+), (+|-) (-|-) each with different therapy approaches. We expected a combined quantitative analysis could improve BC stratification. Methods: Events (E) were defined as death or recurring disease within 5 years, controls being alive without...