- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Pelvic floor disorders treatments
- SARS-CoV-2 and COVID-19 Research
- Anorectal Disease Treatments and Outcomes
- Sepsis Diagnosis and Treatment
- Community Development and Social Impact
- Health and Medical Research Impacts
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- COVID-19 Impact on Reproduction
- Health Sciences Research and Education
- Tracheal and airway disorders
- Endometrial and Cervical Cancer Treatments
- Minimally Invasive Surgical Techniques
- Obstructive Sleep Apnea Research
- COVID-19 diagnosis using AI
- Myofascial pain diagnosis and treatment
- COVID-19 Clinical Research Studies
- Frailty in Older Adults
- Long-Term Effects of COVID-19
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Enhanced Recovery After Surgery
- IgG4-Related and Inflammatory Diseases
- Spine and Intervertebral Disc Pathology
University of Edinburgh
2023-2024
Clinique Ambroise Paré
2023
Université Paris-Saclay
2023
Hôpital Foch
2020-2023
Université de Versailles Saint-Quentin-en-Yvelines
2021
École Nationale Supérieure d'Ingénieurs de Caen
2021
Normandie Université
2021
Institut National de Physique Nucléaire et de Physique des Particules
2021
Université de Caen Normandie
2021
Laboratoire de Physique Corpusculaire de Caen
2021
International guidelines recommend IV crystalloid as the primary fluid for sepsis resuscitation, with 5% human albumin solution (HAS) second line. However, it is unclear which has superior clinical effectiveness. We conducted a trial to assess feasibility of delivering randomized controlled comparing balanced against HAS sole early resuscitation in patients presenting hospital.
Robotic surgery data need a setback on many years of practice with high-volume surgeons to evaluate its real value. Our main objective was study the impact decade robotic minimally-invasive hysterectomies for benign indications. secondary objectives were our results and complex cases.In this retrospective cohort study, we reviewed medical records at Foch Hospital, from 2010 2019, outcomes disease. We compared trends done by laparoscopy laparotomy during period. analyzed proficiency group (≥...
Abstract Aim To extend the findings of a previous clinical trial suggesting combined abacavir (ABC), lamivudine (3TC), and zidovudine (AZT) reduces type I interferon (IFN) signalling in Aicardi–Goutières syndrome (AGS). Method This was an open label, non‐placebo‐controlled phase II (NCT04731103) patients less than 16 years with any five AGS genotypes. The effect ABC or 3TC individually, + AZT, on IFN‐stimulated gene (ISG) expression (primary outcome) IFN‐alpha protein (secondary blood...
The purpose of our work was to assess the independent and incremental value AI-derived quantitative determination lung lesions extent on initial CT scan for prediction clinical deterioration or death in patients hospitalized with COVID-19 pneumonia. 323 consecutive (mean age 65 ± 15 years, 192 men), laboratory-confirmed an abnormal chest scan, were admitted hospital between March December 2020. consolidation all opacities quantified using a 3D automatic AI-based software. outcome known these...
The COVID-19 pandemic has occurred due to infection caused by the SARS-CoV-2 coronavirus, which impacts gestation and pregnancy. In infection, only very rare cases of vertical transmission have been reported, suggesting that fetal immune imprinting a maternal is probably result changes in immunity. Natural killer (NK) cells are leading act as natural defense system fight infections. They also play pivotal role establishment maintenance While peripheral NK display specific features patients...
At the start of 2021, oncologists lacked necessary scientific knowledge to adapt their clinical practices optimally when faced with cancer patients refusing or reluctant be vaccinated against COVID-19, despite marked vulnerability these severe, and even fatal forms this new viral infectious disease. Oncologists at Foch Hospital were confronted phenomenon, which was observed worldwide, in both general population patients.
The preoperative period may be an opportune to optimize patients' physical condition with a multimodal program. impact of "prehabilitation" program on elderly patients is discussed. This mono-center observational cohort study included consecutively 139 planned for major abdominal and thoracic surgery, 44 in the control group (age < 65) 95 > 65). All followed including exercise training, nutritional optimization, psychological support, behavioral change. Seventeen 45 completed at six months....
In the context of SARS-CoV-2 pandemic, our interest was to evaluate effect COVID-19 during pregnancy on placenta and coagulation factors.a prospective cohort study between January July 2021 55 pregnant women stratified into: Group O, 16 patients with ongoing infection at delivery; R, 21 a history but who recovered prior C, 18 control no any time. All had nasopharyngeal RT-PCR tests performed within 72 h delivery. Obstetrical complications were recorded two physiological inhibitors...
Less-invasive thoracotomies may reduce early postoperative pain. The aims of this study were to identify pain trajectories from days 0–5 after posterolateral and axillary potential factors related the worst trajectory. Patients undergoing a (92 patients) or (89 thoracotomy between July 2014 November 2015 analyzed in prospective monocentric cohort study. best-fitting model resulted four trajectory groups: 1, “worst”, with 29.8% patients permanent significant pain; 2 low (32.6%); 3 steep...
Objective We hypothesised that videolaryngoscopy modifies practice of tracheal intubation. Design Randomised single-blinded study (video and no-video groups). Setting Three institutions: one academic, non-profit profit. Participants Patients >18 years, requiring orotracheal intubation, without predicted difficult Non-inclusion criterion was patients a rapid-sequence 300 were included, 271 randomised, 256 analysed: 123 in the 133 video groups. Intervention Tracheal intubation using McGrath...
We aimed to demonstrate the antalgic effectiveness of ScenarTM (Self-Controlled Electro Neuro Adaptative Regulation) in patients experiencing low back and neck pain. Sixty were included equally assigned by randomization a Scenar-On group Scenar-Off (sham group). All received 20 min application on area where they experienced The pain at rest during movement sensation stiffness assessed using numeric rating scale baseline, immediately after session 24 h session. patients' characteristics entry...
Abstract Purpose International guidelines recommend intravenous crystalloid as the primary fluid for sepsis resuscitation, with 5% human albumin solution (HAS) second line. However, it is unclear which has superior clinical effectiveness. We conducted a feasibility trial comparing HAS balanced in early resuscitation of adults UK Emergency Departments (EDs), to investigate recruitment metrics and determine event rates inform subsequent design. Methods Multicentre, open, parallel-group...