A5082327592- Diet, Metabolism, and Disease
- Enzyme Structure and Function
- Liver Disease Diagnosis and Treatment
- Pancreatic function and diabetes
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Microbial Metabolites in Food Biotechnology
- Carbohydrate Chemistry and Synthesis
- Biofuel production and bioconversion
- Amino Acid Enzymes and Metabolism
- Diet and metabolism studies
- Plant nutrient uptake and metabolism
- Microbial Metabolic Engineering and Bioproduction
- Polyamine Metabolism and Applications
- Digestive system and related health
- Metabolism, Diabetes, and Cancer
- Enzyme Production and Characterization
- Biochemical Acid Research Studies
- Sugarcane Cultivation and Processing
- Freezing and Crystallization Processes
- Biochemical and Molecular Research
- Glycosylation and Glycoproteins Research
- Advanced Glycation End Products research
- Cancer, Hypoxia, and Metabolism
- Erythrocyte Function and Pathophysiology
Kagawa University
2015-2024
Matsutani (Japan)
2016
Tianjin Institute of Industrial Biotechnology
2013-2014
Chinese Academy of Sciences
2013-2014
University of Toyama
2011-2012
University of Oxford
2011-2012
Kagawa University Hospital
2012
Kyoto University
2008
Kanagawa Industrial Technology Center
2006
University of Arkansas for Medical Sciences
1996
D-Psicose (D-ribo-2-hexulose), a C-3 epimer of D-fructose, is present in small quantities commercial carbohydrate complexes and agricultural products. We have previously reported that D-psicose supplements diets suppressed hepatic lipogenic enzyme activity. The lower fat accumulation rats fed may be due to lipogenesis the liver. study examined energy available for rat growth. Male Wistar received 7g daily basal diet which fixed amounts sucrose, or (0.5-2.0g) were added 20 d. Body weight gain...
The effect of nonenzymatic glycation on the structural changes and gelling properties hen ovalbumin (OVA) through Maillard reaction was studied. OVA incubated at dry state with a rare ketohexose (d-psicose, Psi) two alimentary sugars (d-fructose, Fru; d-glucose, Glc) 55 °C 65% relative humidity. To evaluate modification by different reducing during process, extent reaction, aggregation processes, changes, behaviors were investigated. Reactivity Psi protein amino groups much lower than that...
A new enzyme, D-tagatose 3-epimerase, was found in Pseudomonas sp. ST-24 during the course of studies on D-sorbose fermentation. This enzyme catalyzes epimerization keto-sugars, for example between and D-sorbose, D-fructose D-psicose. It shown that this epimerizes configuration at C-3 position these substrates. epimerase didn't act 6-phosphate D-ribulose 5-phosphate. The has been purified from cells grown a medium containing 1% D-glucose 0.05% D-tagatose, it appeared homogeneous...
An examination was conducted to verify D-psicose suppressed the elevation of blood glucose and insulin concentration in a dose-dependent manner under concurrent administration maltodextrin healthy humans. Twenty subjects aged 20-39 y, 11 males 9 females were recruited. A load test oral as randomized single blind study. The took one five beverages (7.5 g alone, 75 +2.5, 5 or 7.5 D-psicose). Blood collected before an intake at 30, 60, 90 120 min after intake. Intervals least 1 wk. with showed...
D‐Psicose ( D ‐ ribo ‐2‐hexulose), a C‐3 epimer of ‐fructose, is present in small quantities commercial carbohydrate complexes or agricultural products. Wistar male rats were fed experimental diets which consisted 5% ‐psicose, cellulose, ‐fructose ‐glucose for 28 days. Abdominal adipose tissue weight was significantly lower P < 0.05) the ‐psicose diet than and diets, even though four dietary groups offered same amount throughout period. Fatty acid synthase glucose 6‐phosphate...
To elucidate the history of human exposure psicose, a determination method psicose (D/L-psicose) in various food products has been developed : post column high-performance liquid chromatography (HPLC) using gel permeation ligand exchange mode coupled with pulsed amperometric detection (PAD). The calibration curve D-psicose was linear concentration range 5 to 150μg/ml correlation coefficient 0.9999. With ultrasonic extraction and C18 Sep-pack filtration methods, samples for HPLC analysis...
The effects of supplemental D-psicose in the diet on diurnal variation plasma glucose and insulin concentrations were investigated rats. Forty-eight male Wistar rats divided into four groups. Each group except for control was fed a 5% D-fructose, D-psicose, or psico-rare sugar (3:1 mixture D-fructose D-psicose) 8 weeks. Plasma levels lower higher at all times day psicose groups than fructose Weight gain significantly Liver glycogen content, both before after meals These results suggest that...
d-Psicose (Psi) might be an ideal sucrose (Suc) substitute for food products due to its sweet taste, easy processing, and functional properties (noncaloric low glycemic response). In the present study, effects of Psi on foaming egg white (EW) protein quality butter cookies were analyzed find a better use in aerated systems. The results showed that could improve EW with increasing whipping time comparison Suc d-fructose (Fru). addition cookies, as partial replacement Suc, had no influence...
Abstract X-ray crystal analysis for d-psicose (C3-position epimer of d-fructose) crystallized from aqueous solution was successfully performed the first time. It confirmed that solely as β-d-pyranose with 1C (1C4 (d)) conformation. The system (orthorhombic), space group (#19, P212121), and number molecules per unit cell (Z = 4) are same those β-d-fructopyranose, α-l-sorbopyranose, α-d-tagatopyranose. Solubility at 25 °C 291 g 100 water. Mutarotation further investigated recording time course...
External control of gene expression is crucial in synthetic biology and biotechnology research applications, commonly achieved using inducible promoter systems. The E. coli rhamnose-inducible rhaBAD has properties superior to more used systems, but marred by transient caused degradation the native inducer, l-rhamnose. To address this problem, 35 analogues l-rhamnose were screened for induction promoter, no strong inducers identified. In configuration, an inducer must bind activate two...