A5066618509- Inflammatory Biomarkers in Disease Prognosis
- Spondyloarthritis Studies and Treatments
- Cancer Treatment and Pharmacology
- Colorectal Cancer Treatments and Studies
- Cancer Diagnosis and Treatment
- Cancer survivorship and care
- Nutrition and Health in Aging
- Ovarian cancer diagnosis and treatment
- Inflammasome and immune disorders
- Lung Cancer Treatments and Mutations
- Neuroendocrine Tumor Research Advances
- Cancer, Lipids, and Metabolism
- Breast Cancer Treatment Studies
- Cancer Risks and Factors
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Bone and Joint Diseases
- Sarcoma Diagnosis and Treatment
- Testicular diseases and treatments
- Endometrial and Cervical Cancer Treatments
- Ovarian function and disorders
- Renal cell carcinoma treatment
- Multiple and Secondary Primary Cancers
Izmir Kâtip Çelebi University
2016-2025
Weatherford College
2023
Izmir Atatürk Eğitim ve Araştırma Hastanesi
2015-2019
Muğla University
2016
Gaziantep University
2016
Usak University
2016
Marmara University
2016
Manisa Celal Bayar University
2016
Erciyes University
2016
Afyon Kocatepe University
2016
Objective The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score the Geriatric Nutrition Risk Index (GNRI) are used as prognostic factors in different types of cancers. In this study we analyzed value HALP GNRI calculated prior to first-line treatment patients diagnosed with de novo metastatic non-small cell lung cancer (mNSCLC). Materials methods De mNSCLC were retrospectively evaluated from January 2016 December 2019. Patients Driver’s mutation, severe comorbidities, active...
To analyze Fetuin-A levels and soluble cellular adhesion molecules in patients with acute coronary syndrome.Serum intercellular molecule-1 (sICAM-1), vascular (sVCAM-1) were examined 127 who presented chest pain. These classified three groups: stable angina (SA, n=51), myocardial infarction (MI, n=34) non-cardiac group (n=42). Logarithmic transformations made for levels. Log-Fetuin-A higher subjects compared to MI SA (p<0.05). Patients showed lower than controls but as patients. After...
We aimed to investigate anxiety, depression and sexual satisfaction levels the effects of anxiety upon Turkish breast cancer patients their partners.Data were collected from one hundred partners, using three forms: covering information about socio-demographic characteristics patients, Hospital Anxiety Depression Scale (HADs) Golombok-Rust Inventory Sexual Satisfaction (GRISS).The frequencies, avoidance touch subscores statistically significantly high in patients. Among those with scores,...
To investigate the variables of quality life (QoL) among Turkish patients with colorectal cancer (CRC).In this prospective study we investigated QoL CRC patients. Two hundred and twenty two were included. The sociodemographic form European Organization for Research Treatment Cancer Quality Life Questionnaire (EORTC QLQ-C30) used.The group consisted 142 males (64%) 80 females (36%). mean patient age was 55.68±11.387 years. majority (36.9%) had local disease while advanced-stage locally...
Objective Endothelial dysfunction is present in ankylosing spondylitis (AS). However, the etiology of events still unclear. The aim study was to investigate whether there are abnormalities nitric oxide (NO) metabolism and endothelin-1 (ET-1) AS patients. Methods Subjects without any classical cardiovascular (CV) risk factors were studied. Fasting glucose, serum lipids, high sensitive CRP (hsCRP), ESR, asymmetric dimethylarginine (ADMA) ET-1 Patients also evaluated with Bath Ankylosing...
249 Background: Urotensin-II is a small somatostatin-like cyclic peptide characterized by its potent vasoconstrictor activity. (UT-II) and receptor (UTR) have been shown to play role in the formation of different epithelial cancers. To date, many studies reported prostate cancer that provide genetic contributions with diagnostic, prognostic therapeutic potential for carcinogenesis. However, urotensin-II carcinogenesis has not yet elucidated. There are several limitations using PSA as...
Long-term survival is a problem with locally advanced and metastatic renal cell carcinomas. Sunitinib malate an oral multitargeted tyrosine kinase inhibitor, but data on sunitinib use as second line treatment in carcinoma (mRCC) are limited. Prognostic predictive value of peripheral blood markers has been shown for many cancers.Efficacy safety profiles after interferon alpha were evaluated based retrospective 23 patients mRCC. Hematological parameters (neutrophils, lymphocytes, platelets,...
Background: The purpose of this study was to analyze the predictive value neutrophil/lymphocyte ratio (NLR) better clarify which patient groups will benefit most from particular treatments like bevacizumab. Materials and Methods: A total 245 treatment-naive metastatic colorectal cancern (mCRC) patients were retrospectively enrolled divided into 2 groups: 145 group treated with chemotherapy in combination bevacizumab, 100 B as above without Results: Group had median overall survival (OS)...
Objective To determine if EE/CA and plus metformin treatment have any effect on adhesion molecules in cases with PCOS. Methods Among 40 patients diagnosed PCOS, one study arm was administered (n=20, cyproterone acetate 2 mg, ethinylestradiol 35 μg) the other (1,700 mg) combined μg). Soluble intercellular molecule-1 (sICAM-1), soluble endothelial leukocyte (sE-selectin), vascular cell (sVCAM-1), molecule-3 (sP-selectin), lipid profile, androgens, insulin, HOMA-IR values were assessed prior to...
BACKGROUND: In early breast cancer patients, the effects of hormonal therapy (tamoxifen and aromatase inhibitors) on plasma fibroblast growth factor 21 (FGF-21), lipid levels body composition have not yet been investigated. Therefore, we aimed to analyze relationship between FGF-21 as well tamoxifen inhibitors levels, FGF-21, composition. METHODS: A total 72 patients were treated with either or due their menopausal status after adjuvant radiotherapy. Each patient was followed-up over a...
A limited number of studies have been conducted on the effects hormonal therapy with tamoxifen (TMX) or aromatase inhibitors (AIs) plasma levels leptin and adiponectin, as well body composition in breast cancer (BC) patients. Therefore, we aimed to analyze relationship between adipocytokines TMX AIs leptin, leptin/adiponectin ratio (LAR) composition.Patients were treated either AI according their menopausal status after adjuvant radiotherapy. Changes serum adiponectin evaluated. We recorded...
Triple-negative breast cancer (TNBC) and HER2-positive are more aggressive than other subtypes of cancer. Due to the limited number treatment alternatives absence target receptors in TNBC, because progression group despite targeted treatments, new targets therapeutic combinations required. In this context, present study aims evaluate prognostic importance immunohistochemical androgen receptor (AR) expression TNBC subtypes. AR nuclear staining density was evaluated immunohistochemically. A...
Objective. To evaluate the profiles of endothelial microparticles (EMP) and platelet (PMP) in men with ankylosing spondylitis (AS) healthy subjects. We also aimed to determine whether (MP) correlate disease activity, function, spinal mobility indices. Methods. There were 82 AS 53 controls. Subjects a history chronic diseases including coronary artery disease, hypertension, diabetes mellitus, dyslipidemia excluded. MP stained monoclonal antibodies against platelets cells quantified using flow...
Abstract Aim: Interleukin‐18 (IL‐18) and fetuin‐A have been implicated in atherosclerosis. Preliminary evidence suggests that ankylosing spondylitis (AS) is associated with an increased risk of The aim the present study was to investigate possible abnormalities IL‐18 levels AS. Methods: Subjects without established cardiovascular (CV) factors were studied. Fasting glucose, serum lipids, high sensitive C‐reactive protein (hsCRP), erythrocyte sedimentation rate, assessed. Patients also...
The role of second-line therapy in metastatic pancreatic cancer is not clear. In this study, we aimed to explore the efficiency capecitabine and oxaliplatin (XELOX) patients with advanced who have received gemcitabine-based first-line therapy.We retrospectively evaluated 47 locally or previously treated regimens. Treatment consisted 130 mg/m2 1000 twice daily a 3 week interval, until unacceptable toxicity disease progression.Median number cycles was 4 (range, 2-10). overall control rate...