Hak Hee Kim

ORCID: 0000-0002-2956-9212
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About
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Research Areas
  • Breast Lesions and Carcinomas
  • Breast Cancer Treatment Studies
  • MRI in cancer diagnosis
  • Radiomics and Machine Learning in Medical Imaging
  • Digital Radiography and Breast Imaging
  • AI in cancer detection
  • Medical Imaging Techniques and Applications
  • Cancer and Skin Lesions
  • Breast Implant and Reconstruction
  • Reconstructive Surgery and Microvascular Techniques
  • HER2/EGFR in Cancer Research
  • Global Cancer Incidence and Screening
  • Advanced MRI Techniques and Applications
  • Photoacoustic and Ultrasonic Imaging
  • Advanced Neuroimaging Techniques and Applications
  • Advanced X-ray and CT Imaging
  • Cancer Diagnosis and Treatment
  • Cancer Treatment and Pharmacology
  • Ultrasound Imaging and Elastography
  • Optical Imaging and Spectroscopy Techniques
  • Ultrasound and Hyperthermia Applications
  • Nerve injury and regeneration
  • Salivary Gland Tumors Diagnosis and Treatment
  • Electrospun Nanofibers in Biomedical Applications
  • Lymphoma Diagnosis and Treatment

University of Ulsan
2016-2025

Asan Medical Center
2016-2025

Ulsan College
2016-2025

Breast Center
2023

Eulji University Hospital
2022

Sun Moon University
2021-2022

Gangneung Asan Hospital
2020

Research Institute of Radiology
2012-2019

Chung-Ang University Hospital
2018-2019

Alfred I. duPont Hospital for Children
2013-2018

BackgroundMammography is the current standard for breast cancer screening. This study aimed to develop an artificial intelligence (AI) algorithm diagnosis of in mammography, and explore whether it could benefit radiologists by improving accuracy diagnosis.MethodsIn this retrospective study, AI was developed validated with 170 230 mammography examinations collected from five institutions South Korea, USA, UK, including 36 468 positive confirmed biopsy, 59 544 benign biopsy (8827 mammograms)...

10.1016/s2589-7500(20)30003-0 article EN cc-by-nc-nd The Lancet Digital Health 2020-02-06

Purpose The radial k‐space trajectory is a well‐established sampling used in conjunction with magnetic resonance imaging. However, the requires large number of lines for high‐resolution reconstruction. Increasing causes longer acquisition time, making it more difficult routine clinical use. On other hand, if we reduce lines, streaking artifact patterns are unavoidable. To solve this problem, propose novel deep learning approach domain adaptation to restore MR images from under‐sampled data....

10.1002/mrm.27106 article EN Magnetic Resonance in Medicine 2018-02-04

Increasing evidence points to the importance of local protein synthesis for axonal growth and responses axotomy, yet there is little insight into functions individual locally synthesized proteins. We recently showed that expression a reporter mRNA with axonally localizing β-actin 3′UTR competes endogenous GAP-43 mRNAs binding ZBP1 localization in adult sensory neurons (Donnelly et al., 2011). Here, we show can deplete axons mRNA. took advantage this competition address In cultured rat...

10.1523/jneurosci.1722-12.2013 article EN cc-by-nc-sa Journal of Neuroscience 2013-02-20

<h3>Importance</h3> Younger women (aged ≤50 years) who underwent breast conservation therapy may benefit from magnetic resonance imaging (MRI) screening as an adjunct to mammography. <h3>Objective</h3> To prospectively determine the cancer yield and tumor characteristics of combined mammography with MRI or ultrasonography in for cancers were 50 years younger at initial diagnosis. <h3>Design, Setting, Participants</h3> This multicenter, prospective, nonrandomized study was conducted December...

10.1001/jamaoncol.2017.1256 article EN JAMA Oncology 2017-06-27

To evaluate the mammographic and sonographic findings of pregnancy-associated breast cancer.A total 22 consecutive patients with cancer pathologically diagnosed during pregnancy (n = 10) or lactation 12) were included in this study. The ages ranged from 26 to 49 years. Both mammography sonography performed on 12 patients; only was 7 3 patients. Mammographic evaluated retrospectively.Mammography revealed positive 13 (86.7%) 15 patients, even though all had dense breasts. masses 5),...

10.7863/jum.2003.22.5.491 article EN Journal of Ultrasound in Medicine 2003-05-01

Purpose The purpose of this work was to describe the radiologic and clinical manifestations n-butyl-2-cyanoacrylate pulmonary embolism (PE) after endoscopic injection sclerotherapy (EIS) for gastric variceal bleeding. Method From 1992 1999, medical records 140 patients who had undergone EIS using were reviewed identification respiratory symptoms amount injection, their pre-and postprocedure chest radiographs identify PE. In with PE, (6/6), CT scans (3/6), lung perfusion follow-up (6/6)...

10.1097/00004728-200101000-00003 article EN Journal of Computer Assisted Tomography 2001-01-01

The objective of our study was to retrospectively assess the potential role sonographic features and biopsy in management patients with papillary lesions diagnosed at percutaneous sonographically guided biopsy.Surgical or follow-up (> = 2 years) available 123 women (age range, 21-75 years; mean age, 47 124 core needle vacuum-assisted during a 7-year period. Surgical excision results sonograms no change 2-year served as reference standard. We reviewed features, results, surgical follow-up....

10.2214/ajr.07.2664 article EN American Journal of Roentgenology 2008-02-21

The purpose of this study was to prospectively evaluate interobserver agreement on lesion detection and characterization in the review automated ultrasound images breast by five radiologists.From August October 2009, bilateral whole-breast examinations were performed with an technique a handheld device for 55 women consecutively scheduled undergo diagnostic ultrasound. Three-dimensional volume data from reviewed radiologists, who unaware results mammography clinical information. If detected...

10.2214/ajr.10.5841 article EN American Journal of Roentgenology 2011-08-23

Localized translation of axonal mRNAs contributes to developmental and regenerative axon growth. Although untranslated regions (UTRs) many different appear drive their localization, there has been no consensus RNA structure responsible for this localization. We recently showed that limited expression ZBP1 protein restricts localization both β-actin GAP-43 mRNAs. 3'UTR a defined element interaction with ZBP1, but mRNA shows homology sequence. Here, we show an AU-rich regulatory (ARE) in...

10.1111/jnc.12266 article EN Journal of Neurochemistry 2013-04-15

Diffuse optical tomography (DOT) has been investigated as an alternative imaging modality for breast cancer detection thanks to its excellent contrast hemoglobin oxidization level. However, due the complicated non-linear photon scattering physics and ill-posedness, conventional reconstruction algorithms are sensitive parameters such boundary conditions. To address this, here we propose a novel deep learning approach that learns obtains accurate three dimensional (3D) distribution of...

10.1109/tmi.2019.2936522 article EN IEEE Transactions on Medical Imaging 2019-08-22

The purpose of this study was to evaluate the use and performance supplemental screening whole-breast sonography in conjunction with mammography asymptomatic women dense breast tissue.A total 28,796 underwent mammography. Among 20,864 breasts (72%), 8359 additional as part their examinations. We classified mammographically into mammography-only mammography-plus-sonography groups. reference standard a combination pathologic results clinical follow-up at 2 years. compared recall rate, cancer...

10.7863/ultra.32.9.1573 article EN Journal of Ultrasound in Medicine 2013-08-26

The purpose of this study is to retrospectively evaluate the relationships between BRCA mutation types, imaging features, and pathologic findings breast cancers in BRCA1 BRCA2 carriers.We identified patients with cancer gene mutations from January 2000 December 2014. After excluding who underwent lesion excision before MRI, 99 103 lesions 187 women (mean age, 39.7 40.4 years, respectively) were enrolled. Mammographic, sonographic, MRI scans reviewed according BI-RADS lexicon (5th edition)....

10.2214/ajr.16.16957 article EN American Journal of Roentgenology 2017-08-10

An increasing number of patients with breast cancer receiving neoadjuvant chemotherapy (NACT) undergo immediate reconstruction (IBR) nipple-sparing mastectomy (NSM) or skin-sparing (SSM) as surgical treatment. However, the oncologic efficacy and safety this treatment sequencing strategy is unclear.To compare long-term outcomes IBR NSM/SSM conventional (CM) alone for in NACT setting.A retrospective, propensity score-matched case-control study was conducted at Asan Medical Center, Seoul,...

10.1001/jamasurg.2020.4132 article EN JAMA Surgery 2020-10-14

The purpose of this article is to describe imaging features the following genitourinary tract locations that can involve inflammatory pseudotumor: kidney, adrenal gland, retroperitoneum or pelvis, bladder, and other rare locations.Although definite radiologic differentiation from malignancy not clearly possible, we suggest familiarity with manifestations pseudotumor help avoid unnecessary radical surgery before histopathologic proof obtained.

10.2214/ajr.07.3663 article EN American Journal of Roentgenology 2008-09-19

The aim of this study was to determine whether tumor size, MRS parameters and apparent diffusion coefficient (ADC) measurements could be applied predict pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC). Ninety patients with breast cancer (median 4.5 cm; range, 1.6–9.5 cm) were evaluated single‐voxel 1 H dynamic contrast‐enhanced MRI. Diffusion‐weighted imaging performed in 41 these using a 1.5‐T scanner before completion NAC. Pre‐ post‐treatment changes [absolute...

10.1002/nbm.2807 article EN NMR in Biomedicine 2012-05-06

The purpose of this article is to determine whether the peak integral and signal-to-noise ratio (SNR) total choline-containing compounds obtained by MR spectroscopy (MRS) correlate with histologic biomarkers currently used for predicting prognosis in patients breast cancer.Single-voxel proton MRS using a 1.5-T scanner was performed 184 (mean age, 48 years; range, 28-72 years) cancer. We absolute compound integral, normalized volume interest, SNR after MRI. On surgical pathology, pathologic...

10.2214/ajr.11.7292 article EN American Journal of Roentgenology 2012-04-23

Objectives To evaluate the value of vascular index (VI) on Superb Microvascular Imaging (SMI; Canon Medical Systems Corporation, Tokyo, Japan) in comparison with grayscale ultrasound (US) alone for assessing breast masses. Methods We evaluated a total 70 masses (36 malignant and 34 benign lesions) consecutive patients using US SMI. Two radiologists analyzed combination They also measured VI based The diagnostic performance SMI was compared. compared between masses, optimal cutoff determined....

10.1002/jum.15441 article EN Journal of Ultrasound in Medicine 2020-08-20
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