A5059264630- Neurobiology and Insect Physiology Research
- Insect and Arachnid Ecology and Behavior
- Insect Utilization and Effects
- Animal Behavior and Reproduction
- Insect Resistance and Genetics
- Insect and Pesticide Research
- Plant and animal studies
- Physiological and biochemical adaptations
- Insect-Plant Interactions and Control
- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Nuclear Physics and Applications
- Invertebrate Immune Response Mechanisms
- Particle accelerators and beam dynamics
- Hemiptera Insect Studies
- Silk-based biomaterials and applications
- Insect Pheromone Research and Control
- Particle Accelerators and Free-Electron Lasers
- Antioxidant Activity and Oxidative Stress
- Insect Pest Control Strategies
- Nuclear physics research studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Viral Infectious Diseases and Gene Expression in Insects
- Silkworms and Sericulture Research
University of Washington
2009-2024
Howard Hughes Medical Institute
2008-2018
Janelia Research Campus
2008-2018
Helix (United States)
2008-2018
Seattle University
1976-2009
University of Michigan
2009
University of California, Davis
2009
Northern Arizona University
2009
University of Massachusetts Amherst
2009
University of Oklahoma
2009
ABSTRACT The moulting process of insects is governed by the interaction three hormones: prothoracicotropic hormone (PTTH), juvenile hormone, and ecdysone (see Doane, 1973; Wyatt, 1972; Wigglesworth, 1971 for recent reviews). To initiate moult brain releases PTTH which causes secretion from prothoracic glands. Ecdysone in turn triggers detachment epidermis old cuticle subsequent new cuticle. Whether this larval, pupal, or adult depends on titre at time secretion.
Behavioral and electrophysiological evidence has suggested that sex pheromone is rapidly inactivated within the sensory hairs soon after initiation of action-potential spike. We report isolation characterization a sex-pheromone-degrading enzyme from silkmoth Antheraea polyphemus. In presence this at physiological concentration, [(6E,11Z)-hexadecadienyl acetate] an estimated half-life 15 msec. Our findings suggest molecular model for reception in which previously reported pheromone-binding...
An adult moth sheds its pupal skin only during a specific period of the day. The brain is necessary for synchronization this behavior with environmental photoperiod. This function fully preserved when all brain's nervous connections are severed or "loose" transplanted into tip abdomen. By appropriate experiments it was possible to show that entire mechanism brain-centered. components include photoreceptor mechanism, clock, and neuroendocrine output. clock-controlled release hormone acts on...
Significance Understanding how organisms regulate their body size is a fundamental problem in biology. Body regulation involves the careful integration of mechanisms that control growth rate with those duration. In insects, developmental hormones such as juvenile hormone and ecdysone transitions The conserved insulin-signaling pathway regulates rates. Our studies reveal an intimate link between three, whereby controls by regulating synthesis, which turn modifies insulin signaling....
Developmental, genetic and endocrine data from diverse taxa provide insight into the evolution of insect metamorphosis. We equate larva–pupa–adult Holometabola to pronymph–nymph–adult hemimetabolous insects. The pronymph is a cryptic embryonic stage with unique endocrinology behavioural modifications that probably served as preadaptations for larva. It develops in absence juvenile hormone (JH) primordia undergo patterning morphogenesis, processes were arrested Embryonic JH then drives tissue...
The understanding of the molecular basis endocrine control insect metamorphosis has been hampered by profound differences in responses Lepidoptera and Diptera to juvenile hormone (JH). In both Manduca Drosophila, broad (br) gene is expressed epidermis during formation pupa, but not adult differentiation. Misexpression BR-Z1 either a larval or an molt Drosophila suppressed stage-specific cuticle genes activated pupal genes, showing that br major specifier stage. Treatment with JH mimic at...
Presented is a brief review of the role ecdysteroid and juvenile hormone (JH) receptors in regulation insect larval molting metamorphosis epidermis nervous system, using examples from Manduca sexta Drosophila melanogaster. Ecdysteroids cause molt by combining with ecdysone receptor (EcR) ultraspiracle protein (both members steroid superfamily) to activate directly number regulatory genes whose products both repress ongoing gene expression stimulate associated production new stage cascading...
1. A sensitive and quantitative bioassay for JH is described based on the inhibition of cuticle melanization in larvae black mutant Manduca sexta. The assay down to about 2 x 10-5 µg (20 pg) C18JH.2. Using this assay, titers hemolymph M. sexta from ecdysis fourth instar through first third fifth have been estimated. titer highest immediately after reniains relatively high until initiation last larval molt. During time that molting initiated, concentration 10-8 M terms C18JH equivalents....