António R. Damásio

ORCID: 0000-0002-3067-0393
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About
Contact & Profiles
Research Areas
  • Neural and Behavioral Psychology Studies
  • Memory and Neural Mechanisms
  • Neural dynamics and brain function
  • Neurobiology of Language and Bilingualism
  • Action Observation and Synchronization
  • Neuroscience, Education and Cognitive Function
  • Face Recognition and Perception
  • Functional Brain Connectivity Studies
  • Visual perception and processing mechanisms
  • Psychology of Moral and Emotional Judgment
  • Psychosomatic Disorders and Their Treatments
  • Neuroscience and Neuropharmacology Research
  • Neuroscience and Music Perception
  • Alzheimer's disease research and treatments
  • Multisensory perception and integration
  • Hemispheric Asymmetry in Neuroscience
  • Emotions and Moral Behavior
  • Child and Animal Learning Development
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • EEG and Brain-Computer Interfaces
  • Olfactory and Sensory Function Studies
  • Cognitive Science and Education Research
  • Spatial Neglect and Hemispheric Dysfunction
  • Mental Health and Psychiatry
  • Language, Metaphor, and Cognition

University of Southern California
2015-2024

Southern California University for Professional Studies
2007-2024

Connect
2020

Allen Institute for Brain Science
2019

Escola Superior de Tecnologia da Saúde de Coimbra
2017

Polytechnic Institute of Coimbra
2017

Salk Institute for Biological Studies
1994-2016

Imaging Center
2012-2016

University of Iowa
1998-2015

Laboratoire de Psychologie et NeuroCognition
2014

Deciding advantageously in a complex situation is thought to require overt reasoning on declarative knowledge, namely, facts pertaining premises, options for action, and outcomes of actions that embody the pertinent previous experience. An alternative possibility was investigated: preceded by nonconscious biasing step uses neural systems other than those support knowledge. Normal participants patients with prefrontal damage decision-making defects performed gambling task which behavioral,...

10.1126/science.275.5304.1293 article EN Science 1997-02-28

Examination of temporal lobe structures from Alzheimer patients reveals a specific cellular pattern pathology the subiculum hippocampal formation and layers II IV entorhinal cortex. The affected cells are precisely those that interconnect with association cortices, basal forebrain, thalamus, hypothalamus, crucial to memory. This focal isolates much its input output probably contributes memory disorder in patients.

10.1126/science.6474172 article EN Science 1984-09-14

The somatic marker hypothesis proposes that decision-making is a process depends on emotion. Studies have shown damage of the ventromedial prefrontal (VMF) cortex precludes ability to use (emotional) signals are necessary for guiding decisions in advantageous direction. However, given role amygdala emotional processing, we asked whether also would interfere with decision-making. Furthermore, there might be difference between roles and VMF play To address these two questions, studied group...

10.1523/jneurosci.19-13-05473.1999 article EN cc-by-nc-sa Journal of Neuroscience 1999-07-01

When the landmark patient Phineas Gage died in 1861, no autopsy was performed, but his skull later recovered. The brain lesion that caused profound personality changes for which case became famous has been presumed to have involved left frontal region, questions raised about involvement of other regions and exact placement within vast territory. Measurements from Gage's modern neuroimaging techniques were used reconstitute accident determine probable location lesion. damage both right...

10.1126/science.8178168 article EN Science 1994-05-20

After bilateral ablation of orbital and lower mesial frontal cortices, a patient had profound changes behavior that have remained stable for 8 years. Although he could not meet personal professional responsibilities, his “measurable” intelligence was superior, therefore considered “malingerer.” Neurologic neuropsychological examinations were otherwise intact. CT, MRI, SPET revealed localized lesion the cortices. All other cerebral areas normal structure radioactivity patterns. Such...

10.1212/wnl.35.12.1731 article EN Neurology 1985-12-01

A patient with selective bilateral damage to the amygdala did not acquire conditioned autonomic responses visual or auditory stimuli but declarative facts about which were paired unconditioned stimulus. By contrast, a hippocampus failed conditioning. Finally, both and hippocampal formation acquired neither conditioning nor facts. These findings demonstrate double dissociation of knowledge relative human hippocampus.

10.1126/science.7652558 article EN Science 1995-08-25

ABSTRACT— Recent advances in neuroscience are highlighting connections between emotion, social functioning, and decision making that have the potential to revolutionize our understanding of role affect education. In particular, neurobiological evidence suggests aspects cognition we recruit most heavily schools, namely learning, attention, memory, making, both profoundly affected by subsumed within processes emotion; call these emotional thought . Moreover, from brain‐damaged patients...

10.1111/j.1751-228x.2007.00004.x article EN Mind Brain and Education 2007-03-01

Although lesion and functional imaging studies have broadly implicated the right hemisphere in recognition of emotion, neither underlying processes nor precise anatomical correlates are well understood. We addressed these two issues a quantitative study 108 subjects with focal brain lesions, using three different tasks that assessed naming six basic emotions from facial expressions. Lesions were analyzed as function task performance by coregistration common space, statistical analyses their...

10.1523/jneurosci.20-07-02683.2000 article EN cc-by-nc-sa Journal of Neuroscience 2000-04-01

Critical analysis of postmortem and CT scan data indicates that prosopagnosia is associated with bilateral lesions the central visual system. Those are located in mesial occipitotemporal region functionally symmetric. The prime factor appearance requirement to evoke specific context a given stimulus. “ambiguity” stimulus (the frequency which different members group visually similar) an adjuvant factor. But not human faces. phenomenon appears relation any “ambiguous” whose recognition depends...

10.1212/wnl.32.4.331 article EN Neurology 1982-04-01
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