Meng Wang

ORCID: 0000-0002-3150-4098
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About
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Research Areas
  • Traditional Chinese Medicine Analysis
  • Plant-based Medicinal Research
  • Pharmacological Effects of Natural Compounds
  • Chromatography in Natural Products
  • Phytochemicals and Antioxidant Activities
  • Berberine and alkaloids research
  • Phytochemistry and biological activity of medicinal plants
  • Metabolomics and Mass Spectrometry Studies
  • Spectroscopy and Chemometric Analyses
  • Phytochemistry and Biological Activities
  • Drug-Induced Hepatotoxicity and Protection
  • Analytical Chemistry and Chromatography
  • Drug Transport and Resistance Mechanisms
  • Drug Solubulity and Delivery Systems
  • Plant biochemistry and biosynthesis
  • Natural product bioactivities and synthesis
  • Computational Drug Discovery Methods
  • Bioactive Natural Diterpenoids Research
  • Rheumatoid Arthritis Research and Therapies
  • Ginseng Biological Effects and Applications
  • Advanced Statistical Process Monitoring
  • Pharmacogenetics and Drug Metabolism
  • Advanced Drug Delivery Systems
  • Medicinal Plant Pharmacodynamics Research
  • Medicinal Plants and Bioactive Compounds

Yanshan University
2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2025

Tianjin University of Traditional Chinese Medicine
2016-2025

Beijing Academy of Agricultural and Forestry Sciences
2024-2025

United States Food and Drug Administration
2021-2025

Tianjin haihe hospital
2024-2025

Huaiyin Institute of Technology
2024

Guangxi Normal University
2024

Shaanxi Normal University
2024

Southern University of Science and Technology
2024

Promising targeted therapy options to overcome drug resistance and side effects caused by platinum(II) drugs for treatment in hepatocellular carcinoma are urgently needed. Herein, six novel multifunctional platinum(IV) complexes through linking agents glycyrrhetinic acid (GA) were designed synthesized. Among them, complex 20 showed superior antitumor activity against tested cancer cells including cisplatin than simultaneously displayed good liver-targeting ability. Moreover, can...

10.1021/acs.jmedchem.4c00144 article EN Journal of Medicinal Chemistry 2024-05-10

Penthorum chinense Pursh (Penthoraceae, PCP), a well-known Miao ethnomedicine, has been traditionally used to treat several liver-related diseases, such as jaundice and viral hepatitis. The aims of the present study were evaluate probable properties aqueous extract PCP on carbon tetrachloride (CCl4)-induced acute liver injury in mice.C57BL/6 mice orally administered an (5.15 10.3 g/kg BW) or silymarin (100 mg/kg) once daily for 1 week prior CCl4 exposure. Silymarin serves positive drug...

10.1186/s13020-017-0153-x article EN cc-by Chinese Medicine 2017-10-30

Phellodendri Chinensis Cortex (PCC) and Amurensis (PAC) are increasingly being used as traditional herbal medicines, but they often mistaken for each other. In this study, the fingerprints of PCC from six different geographical sources were obtained by high-performance liquid chromatography, multivariate chemometric methods comprehensive analysis. Two unsupervised pattern recognition models (principal component analysis hierarchical cluster analysis) a supervised model (partial least squares...

10.3390/molecules23092307 article EN cc-by Molecules 2018-09-10

Botanical primary metabolites extensively exist in herbal medicine injections (HMIs), but often were ignored to control. With the limitation of bias towards hydrophilic substances, with strong polarity, such as saccharides, amino acids and organic acids, are usually difficult detect by routinely applied reversed-phase chromatographic fingerprint technology. In this study, a proton nuclear magnetic resonance (1H NMR) profiling method was developed for efficient identification quantification...

10.1371/journal.pone.0105412 article EN cc-by PLoS ONE 2014-08-26

Polygoni Multiflori Radix (PMR) is increasingly being used not just as a traditional herbal medicine but also popular functional food. In this study, multivariate chemometric methods and mass spectrometry were combined to analyze the ultra-high-performance liquid chromatograph (UPLC) fingerprints of PMR from six different geographical origins. A strategy based on curve resolution–alternating least squares (MCR–ALS) three classification proposed UPLC obtained. Common chromatographic problems,...

10.1016/j.jfda.2016.11.009 article EN cc-by-nc-nd Journal of Food and Drug Analysis 2016-12-23

Injection attacks exploit vulnerabilities in how applications handle user input, allowing malicious code to infiltrate the execution environment of web applications, leading severe consequences, such as data leaks and system crashes. Traditional dynamic static detection methods suffer from limitations manual rule or pattern design intraprocedural analysis, lacking capability automatically learn complex features. Meanwhile, deep learning models encounter challenges, feature redundancy...

10.1109/tr.2024.3521381 article EN IEEE Transactions on Reliability 2025-01-01

Abstract To mitigate pollution caused by levofloxacin (LVF) in aquatic environments, a magnetic catalyst, CoFe 2 O 4 /CoFe@BC (CF@BC), was synthesized using loofah‐derived biochar (BC) as support, through coprecipitation followed calcination at high temperatures. CF@BC utilized for the degradation of LVF aqueous solutions containing peroxymonosulfate (PMS), requiring no additional energy input. demonstrates exceptional catalytic performance, even under acidic conditions, achieving rate 98%...

10.1002/slct.202405300 article EN ChemistrySelect 2025-02-01
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