Olufemi Mulkah Ajagun‐Ogunleye

ORCID: 0000-0002-3159-8178
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Research Areas
  • Curcumin's Biomedical Applications
  • Drug-Induced Hepatotoxicity and Protection
  • Pineapple and bromelain studies
  • Medicinal Plants and Neuroprotection
  • Protein Hydrolysis and Bioactive Peptides
  • Insect Utilization and Effects
  • Moringa oleifera research and applications
  • Cholinesterase and Neurodegenerative Diseases
  • Natural Antidiabetic Agents Studies
  • African Botany and Ecology Studies
  • Biochemical effects in animals
  • Lipid metabolism and biosynthesis
  • Nutrition, Genetics, and Disease
  • Neuroscience and Neuropharmacology Research
  • Herbal Medicine Research Studies
  • Food Chemistry and Fat Analysis
  • Phytochemicals and Antioxidant Activities
  • Parasitic Infections and Diagnostics
  • Poisoning and overdose treatments
  • Aluminum toxicity and tolerance in plants and animals
  • Biochemical Acid Research Studies
  • Nigella sativa pharmacological applications
  • Nuclear Receptors and Signaling
  • Fatty Acid Research and Health
  • Retinoids in leukemia and cellular processes

Lagos State University
2023-2024

University of Arizona
2023

Campbell University
2023

Western International University
2021

Kampala International University
2015-2020

The contamination of edible agricultural goods with pesticides, including dichlorvos (DVDP), poses a substantial public health risk, promoting severe morbidity and mortality, especially in developing countries. It has been shown that hesperidin (hesperetin-7-O-rhamnoglucoside or Hes-7-RGlc) preserves cytomembrane, redox, lipid homeostasis; unfortunately, its function on dichlorvos-incited heart damage not investigated. This work explored the ameliorative influence Hes-7-RGlc DVDP-activated...

10.1016/j.toxrep.2024.101698 article EN cc-by-nc-nd Toxicology Reports 2024-07-19

Despite the nutritional value of Theobroma cacao seed (cocoa), antiproliferative activity is yet to be fully elucidated. Therefore, current study investigated antioxidant and potential anticancer activities extract. The in-vitro free radical scavenging was evaluated via DPPH, nitric oxide, lipid peroxidation, reducing power activity. effect cocoa extract on mitotic cell division determined using Allium cepa assay. phytochemical screening revealed presence cardiac glycoside, phenol, tannin,...

10.1111/jfbc.12767 article EN Journal of Food Biochemistry 2019-02-05

Despite the number of nutritional and medicinal plant‐based products that have been studied for decades, there are still many rare underutilized plants biological importance, whose biochemical properties unmatched, especially wild doum palm, Hyphaene thebaica . Therefore, it is necessary to unveil potential advantages fruit thebaica. The edible palm a rich source novel nutraceutical pharmaceutical constituents. It rare, but highly nutritious found in tropics, variety time‐proven healthy...

10.1155/2024/8380215 article EN cc-by Journal of Food Biochemistry 2024-01-01

The liver is a metabolically active organ which prone to oxidative damage. hepatoprotective effect of Nigella sativa (black seed oil extract) on carbon tetrachloride (CCl4)-induced hepatotoxicity in Sprague-Dawley albino rats was determined. There were four groups eight rats; Group 1 (control) administered with distilled water for 28 days, 2 4 ml/kg CCl4 (70% olive oil: 30% CCl4) alternate days days. 3 and orally Olive Blood samples collected biochemical assessment. Liver, kidney, brain...

10.1111/jfbc.13108 article EN Journal of Food Biochemistry 2019-12-10

Ethno-pharmaceutical products have received a lot of international attention in the scientific community management diabetes mellitus (DM). In this study we determined anti-diabetic and high dosage effects Bidens pliosa type 1 DM (T1DM). Methodology: Thirty rats were divided into six groups subgrouped extract non treatment groups. The treated group was subdivided three which 200 mg/kg, 400 mg/ kg 800 mg/kg treatments respectively. blood glucose levels monitored using standard glucometer for...

10.4236/jdm.2015.53018 article EN cc-by Journal of Diabetes Mellitus 2015-01-01

Plant-based products have been utilized for nutritional and medicinal purposes decades. Although the reported benefits of <em>Carica papaya </em>(Pawpaw) leave extract, its role in hematology, brain histology, possible side effect are still areas research deliberation. Thirty (30) male Sprague Dawley rats, divided into three groups, were fed on rat chow normal saline, </em>leaves extract Ruzu bitters, respectively. Blood chemistry, histology assayed to ascertain their...

10.21926/rpn.2301004 article EN cc-by Recent Progress in Nutrition 2023-03-02

1 Department of Anatomy, Faculty Biomedical Sciences, Kampala International University, Western Campus, Bushenyi, Uganda. 2 Medical Laboratory Medicine, Mbarara University Science and Technology, 3 Surgery, Clinical Medicine Dentistry, Microbiology, Biochemistry, 6 Physiology,

10.9734/bjmmr/2015/15959 article EN British Journal of Medicine and Medical Research 2015-01-10

Organophosphorus pesticides such as dichlorvos (DDVP) are often employed to eradicate pests, especially in low and medium-income countries. However, they have several negative impacts on the visceral organs. Astonishingly, curcumin protects organs from detrimental effects of xenobiotics via maintenance redox homeostasis; unfortunately, its role dichlorvos-provoked multi-organ impairment vis-à-vis lipid homeostasis has not been examined. Therefore, this undertaking probed remedial efficacy...

10.4314/dujopas.v10i3a.32 article EN cc-by-nc Dutse Journal of Pure and Applied Sciences 2024-10-25

Background: Ageing is the major risk factor for most non-communicable diseases. It occurs as a result of free radical damage to macromolecules in cell, coupled with environmental stress assaults. In quest identify new anti-ageing bioactive compounds from natural products, and despite therapeutic values Ananas sativa, its activity has not been fully elucidated. Therefore, aim this study was screen crude, methanol fruit extract sativa (MEAS) fractions, bioactivity fly, Drosophila melanogaster...

10.21010/ajtcamv15i3.9 article EN cc-by African Journal of Traditional Complementary and Alternative Medicines 2018-05-30

Obesity is an excessive accumulation of fat which causes several health implications. It a risk factor for most disabilities and non-communicable diseases such as cardiovascular diseases, diabetes, cancer, neurodegenerative etc. The present study aimed to show the effect short long-term supplementation enriched diet with different concentrations omega-3 fatty acid on cerebrospinal fluid (CSF), serum leptin ratio, adiposity lipid profile in albino Wistar rats. Serum-leptin ratios indicators...

10.9734/ijtdh/2020/v41i1930382 article EN International Journal of TROPICAL DISEASE & Health 2020-12-11
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