A5047645743- Phytochemicals and Antioxidant Activities
- Dye analysis and toxicity
- Drug-Induced Hepatotoxicity and Protection
- Effects and risks of endocrine disrupting chemicals
- Edible Oils Quality and Analysis
- Natural Antidiabetic Agents Studies
- Cholesterol and Lipid Metabolism
- Antioxidant Activity and Oxidative Stress
- Reproductive Biology and Fertility
- Anesthesia and Neurotoxicity Research
- Liver Disease Diagnosis and Treatment
- Curcumin's Biomedical Applications
- Chemotherapy-induced organ toxicity mitigation
- Biochemical Analysis and Sensing Techniques
- Water Quality and Pollution Assessment
- Diet, Metabolism, and Disease
- Nutritional Studies and Diet
- Cholinesterase and Neurodegenerative Diseases
- Medicinal Plants and Neuroprotection
- Phytochemistry and biological activities of Ficus species
- Nutrition, Genetics, and Disease
- Nuclear Receptors and Signaling
- Pharmacological Effects of Natural Compounds
- Selenium in Biological Systems
- Seed and Plant Biochemistry
University of Port Harcourt
2025
Federal University of Agriculture
2019-2024
University of Calabar
2019-2023
The agricultural sector faces persistent threats from plant diseases and pests, with Tuta absoluta posing a severe risk to tomato farming by causing up 100% crop loss. Timely pest detection is essential for effective intervention, yet traditional methods remain labor-intensive inefficient. Recent advancements in deep learning offer promising solutions, YOLOv8 emerging as leading real-time model due its speed accuracy, outperforming previous models on-field deployment. This study focuses on...
The contamination of edible agricultural goods with pesticides, including dichlorvos (DVDP), poses a substantial public health risk, promoting severe morbidity and mortality, especially in developing countries. It has been shown that hesperidin (hesperetin-7-O-rhamnoglucoside or Hes-7-RGlc) preserves cytomembrane, redox, lipid homeostasis; unfortunately, its function on dichlorvos-incited heart damage not investigated. This work explored the ameliorative influence Hes-7-RGlc DVDP-activated...
Background: Benign prostatic hyperplasia (BPH) is a prevalent urological condition. The medicinal plant Terminalia catappa has been traditionally utilized for treating diverse ailments. This study explores the phytochemical profile via GC-MS analysis and assesses hepatorenal protective properties of leaf seed extracts in rat model with BPH induction. Methods: was induced rats using testosterone propionate, followed by oral administration (250 500 mg/kg) 28 days. Liver kidney function were...
Earlier reports have shown that Cyclophosphamide (CYCP), an anti-malignant drug, elicited cytotoxicity; and naringin has several beneficial potentials against oxidative stress dyslipidaemias. We investigated the influence of on free radical scavenging, cellular integrity, ATP, antioxidants, stress, lipid profiles in CYCP-induced erythrocytotoxicity rat model. Rats were pretreated orally by gavage for fourteen consecutive days with three doses (50, 100, 200 mg/kg) before single CYCP (200...
Long-term adverse effects on human health are caused by exogenous compounds that alter the functions of biological systems, especially neuroendocrine disruptors like diethyl phthalate (DEP) and bisphenol S (BPS). Although vanillic acid (VA) has pertinent neuropharmacological characteristics, its effect against DEP + BPS-induced neurotoxicity not been explored. This study proposed VA may offer protection BPS. Thirty male Wistar rats were randomly distributed across five groups: a control...
Oxidative stress plays a crucial role in the development of type 2 diabetes and associated microvascular cardiovascular complications. In study, we have investigated effects Heinsia crinita (H. crinita) extracts on lipid peroxidation oxidative responses using diabetic rats. Type was induced with 10 % fructose/40 mg/kg body weight streptozotocin (STZ). H. extract administered at 200 400 twice daily for 21 days, addition to metformin (MET: 500 weight) control. Molecular docking analysis...
Diabetes mellitus and its related complications lead to various systemic alterations. This study aimed evaluate the effect of administration extract Peristrophe bicalyculata (PB) quercetin on diabetic rat models. Forty-eight albino rats (120–150 g) were divided into six groups 8 animals each. The included normal control (NC DC (placebo)), Quercetin (10 mg/kg b.w.), Metformin, low (250 b.w.) high-dose PB (500 administered for 21 days. Administration extracts, metformin recorded a significant...
The proximate constituents and phytochemical compositions of Bambara groundnut (Vigna subterranean) Pigeon pea (Cajanus cajan) underutilized in Calabar, Cross River States was investigated. research will provide solutions to food availability affordability interlock their abundance complex carbohydrates, plant-based proteins, unsaturated fatty acids essential minerals. pigeon obtained from markets Anambra State Ugep, State. plant extracts were assessed for the existence phytochemicals by...
People who expose to mixture of crude oil products had been reported show several diseased-symptoms including hypertension, liver failure and chronic complications. The drugs for treating multiple-complex diseases are scarcely available. Cashew nut snack is known check multiple easily accessible by indigenous-patients with no lethal-effects. Here, we examined the corrective-measures roasted-cashew-nut (RCN) against hypertension co-morbidity liver-failure in male rats on exposure...
Abstract. Eteng OE, Moses CA, Enobong J, Akamo AJ, Akinloye DI, Ugbaja RN, OA. 2020. Protective effects of Curcuma longa rhizomes ethyl acetate extract against alcohol induced oxidative stress and nephrotoxicity in female Wistar rats. Biofarmasi J Nat Prod Biochem 21: 5-12. This study aimed to evaluate the protective effect Linn. (syn. domestica Val.) (CLREAE) facing alcohol-induced nephrotoxicity. Thirty (30) rats were categorized randomly into six groups. Groups 1, 2, 3, 4, 5 6 treated...