A5081924179- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Adrenal and Paraganglionic Tumors
- Inflammasome and immune disorders
- COVID-19 Impact on Reproduction
- Reproductive System and Pregnancy
- Kawasaki Disease and Coronary Complications
- Orthopedic Infections and Treatments
- Viral Infections and Immunology Research
- Osteomyelitis and Bone Disorders Research
- COVID-19 Clinical Research Studies
- interferon and immune responses
Cleveland Clinic Lerner College of Medicine
2022-2024
Case Western Reserve University
2024
Abstract In patients with primary hyperaldosteronism (PA), adrenal vein sampling (AVS) can identify suitable for unilateral adrenalectomy. However, in AVS an indeterminate aldosterone‐to‐cortisol lateralization (ACL) ratio of 3.0–4.0, clinical guidance is unclear. The authors screened all undergoing at the Cleveland Clinic from October 2010 to January 2021 and identified 18 ACL results. Ten underwent adrenalectomy eight continued medical management. surgical group was younger (58.5 vs. 68...
Patients with immune-mediated inflammatory diseases (IMIDs) like rheumatoid arthritis (RA) are at higher risk for severe COVID-19 and long-term complications in bone health. Emerging clinical evidence demonstrated that SARS-CoV-2 infection reduces turnover promotes loss, but the mechanism underlying worsened health remains elusive. This study sought to identify specific immune mediators exacerbated preexisting IMIDs after exposure. Plasma samples from 4 groups were analyzed: healthy, IMID...