A5044405214- Osteoarthritis Treatment and Mechanisms
- Advanced MRI Techniques and Applications
- Lower Extremity Biomechanics and Pathologies
- Medical Imaging Techniques and Applications
- Total Knee Arthroplasty Outcomes
- Dementia and Cognitive Impairment Research
- Knee injuries and reconstruction techniques
- Bone and Joint Diseases
- Alzheimer's disease research and treatments
- Advanced Neuroimaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Sports injuries and prevention
- Hip disorders and treatments
- Functional Brain Connectivity Studies
- Health, Medicine and Society
- Frailty in Older Adults
- Neurological Disease Mechanisms and Treatments
- Shoulder Injury and Treatment
- Orthopedic Infections and Treatments
- Cerebral Palsy and Movement Disorders
- Rheumatoid Arthritis Research and Therapies
- Orthopaedic implants and arthroplasty
- Stroke Rehabilitation and Recovery
Stanford University
2016-2025
University Hospital of Geneva
2013-2023
University of Geneva
2012-2023
Palo Alto University
2007-2023
Center for Clinical Research (United States)
2023
Duke University
2023
University of Alabama at Birmingham
2023
Paris Cardiovascular Research Center
2023
Hôpital Européen Georges-Pompidou
2023
Glenfield Hospital
2023
<b><i>Objective:</i></b> To examine the relationship between stereologic estimates of AD-related pathology and severity cognitive deficits in brain aging. <b><i>Background:</i></b> Previous studies reported substantial contributions neurofibrillary tangles (NFT), amyloid deposits, neuronal loss to development dementia. However, prediction status based on nonstereologic quantification these measures has led conflicting results. Such have measured densities, rather than absolute numbers, most...
Abstract Chemical shift based methods are often used to achieve uniform water–fat separation that is insensitive B o inhomogeneities. Many spin‐echo (SE) or fast SE (FSE) approaches acquire three echoes shifted symmetrically about the SE, creating time‐dependent phase shifts caused by chemical shift. This work demonstrates acquired cause artifacts degrade image quality. According theory, noise performance of any method dependent on proportion water and fat within a voxel, position relative...
Musculoskeletal MRI at 3.0 T: Relaxation Times and Image ContrastGarry E. Gold1, Eric Han2, Jeff Stainsby3, Graham Wright3, Jean Brittain2 Christopher Beaulieu1Audio Available | Share
This work describes a new approach to multipoint Dixon fat-water separation that is amenable pulse sequences require short echo time (TE) increments, such as steady-state free precession (SSFP) and fast spin-echo (FSE) imaging. Using an iterative linear least-squares method decomposes water fat images from source acquired at TE with high signal-to-noise ratio (SNR) uniform of are obtained. algorithm extends multicoil reconstruction minimal additional complexity. Examples single-...
Magnetic resonance imaging (MRI) near metallic implants remains an unmet need because of severe artifacts, which mainly stem from large metal-induced field inhomogeneities. This work addresses MRI with innovative technique called "Slice Encoding for Metal Artifact Correction" (SEMAC). The SEMAC corrects metal artifacts via robust encoding each excited slice against is achieved by extending a view-angle-tilting (VAT) spin-echo sequence additional z-phase encoding. Although the VAT...
To develop a super-resolution technique using convolutional neural networks for generating thin-slice knee MR images from thicker input slices, and compare this method with alternative through-plane interpolation methods.We implemented 3D network entitled DeepResolve to learn residual-based transformations between high-resolution lower-resolution thick-slice at the same center locations. was trained 124 double echo in steady-state (DESS) data sets 0.7-mm slice thickness tested on 17...
Abstract Purpose To combine gradient‐echo (GRE) imaging with a multipoint water–fat separation method known as “iterative decomposition of water and fat echo asymmetry least squares estimation” (IDEAL) for uniform separation. Robust suppression is necessary many GRE applications; unfortunately, challenging in the presence B 0 inhomogeneities. These challenges are addressed IDEAL technique. Materials Methods Echo shifts three‐point were chosen to optimize noise performance estimation, which...
Surgical options for cartilage resurfacing may be significantly improved by advances and application of biomaterials that direct tissue repair. A poly(ethylene glycol) diacrylate (PEGDA) hydrogel was designed to support matrix production, with easy surgical application. model in vitro system demonstrated deposition cartilage-specific extracellular the biomaterial stimulation adjacent development mesenchymal stem cells. For translation joint environment, a chondroitin sulfate adhesive applied...
To determine whether a three-dimensional isotropic resolution fast spin-echo sequence (FSE-Cube) has similar diagnostic performance as routine magnetic resonance (MR) imaging protocol for evaluating the cartilage, ligaments, menisci, and osseous structures of knee joint in symptomatic patients at 3.0 T.This prospective, HIPAA-compliant, institutional review board-approved study was performed with waiver informed consent. FSE-Cube added to 3.0-T MR 100 (54 male median age 32 years 46 female...
Working memory involves the short-term storage and manipulation of information necessary for cognitive performance, including comprehension, learning, reasoning planning. Although electroencephalogram (EEG) rhythms are modulated during working memory, temporal relationship EEG oscillations with eliciting event has not been well studied. In particular, dynamics neural network supporting processes may be best captured in induced oscillations, characterized by a loose link stimulus. order to...
The objective of this study was to determine the sensitivity and specificity clinical criteria for possible vascular dementia (VaD) recently developed independently by two groups: State California Alzheimer's Disease Diagnostic Treatment Centers (ADDTC) National Institute Neurological Disorders Stroke with Association Internationale pour la Recherche et l'Enseignement en Neurosciences (NINDS-AIREN). We also wished compare performance new that Hachinski Ischemic Score (HIS). comprised a...
Patellofemoral pain is a common and debilitating disorder. Elevated cartilage stress of the patellofemoral joint hypothesized to play role in onset pain. Estimating requires accurate measurements contact area. The purpose this study was estimate areas group healthy, pain-free subjects during upright, weight-bearing conditions. Sixteen (8 female, 8 male) were scanned GE Signa SP open configuration MRI scanner, which allowed stand or squat while reclining 25 degrees from vertical with knee...