A5056226057- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- CAR-T cell therapy research
- RNA modifications and cancer
- RNA Research and Splicing
- interferon and immune responses
- Acute Myeloid Leukemia Research
Baylor College of Medicine
2022-2025
<div>Abstract<p>Vα24-invariant natural killer T cells (NKT) possess innate antitumor properties that can be exploited for cancer immunotherapy. We have shown previously the CD62L<sup>+</sup> central memory-like subset of these drives <i>in vivo</i> activity NKTs, but molecular mediators NKT memory differentiation remain unknown. Here, we demonstrate relative to CD62L<sup>–</sup> cells, NKTs express a higher level gene encoding Wnt/β-catenin...
<p>Combined supplementary figures file</p>
<div>Abstract<p>Vα24-invariant natural killer T cells (NKT) possess innate antitumor properties that can be exploited for cancer immunotherapy. We have shown previously the CD62L<sup>+</sup> central memory-like subset of these drives <i>in vivo</i> activity NKTs, but molecular mediators NKT memory differentiation remain unknown. Here, we demonstrate relative to CD62L<sup>–</sup> cells, NKTs express a higher level gene encoding Wnt/β-catenin...
<p>Combined supplementary figures file</p>