A5077181954- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Ovarian function and disorders
- Birth, Development, and Health
- Reproductive System and Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Pregnancy-related medical research
- Health, Medicine and Society
- Reproductive Biology and Fertility
- Endometrial and Cervical Cancer Treatments
- Healthcare Systems and Practices
- Pelvic floor disorders treatments
- Ectopic Pregnancy Diagnosis and Management
- Ovarian cancer diagnosis and treatment
- Maternal and fetal healthcare
- Musculoskeletal pain and rehabilitation
- Female Genital Mutilation/Cutting Issues
- Intestinal and Peritoneal Adhesions
- Maternal and Perinatal Health Interventions
- Intraperitoneal and Appendiceal Malignancies
- Appendicitis Diagnosis and Management
- Bariatric Surgery and Outcomes
- Cardiovascular Issues in Pregnancy
Centre hospitalier régional de la Citadelle
2017-2025
University of Liège
2010-2025
Centre Hospitalier Universitaire de Liège
2014-2024
Yale University
2022
Abstract Background Estriol (E 3 ) is a steroid hormone formed only during pregnancy in primates including humans. Although E synthesized at large amounts through complex pathway involving the fetus and placenta, it not required for maintenance of has classically been considered virtually inactive due to associated very weak canonical estrogen signaling. However, exposure may have an effect on organs both within outside reproductive system, compounds with binding affinity receptors weaker...
Deep infiltrating endometriosis (DIE) responds variably to hormonal therapy. Mutations in cancer driver genes have been identified a fraction of the ectopic endometrial epithelial cells, suggesting functional heterogeneity these lesions. To evaluate phenotype cells DIE, we measured expression estrogen receptor α (ERα) and progesterone (PR) DIE untreated women or under various treatments. We analyzed luminal height (LEH), immunoreactive staining (IRS) stromal intensity (SSI) ERα PR. observed...
VA-2914 is a selective progesterone receptor modulator with potential contraceptive activity that induces amenorrhea, whereas progestins cause endometrial spotting and bleeding. This abnormal bleeding due to consequence of focal stromal proteolysis by an increase in naked vessel size density.Our objective was quantify the effects on vascularization, fibrillar matrix, vascular endothelial growth factor (VEGF)-A expression biopsies from 41 women before after 12 wk daily treatment placebo, or...
Chronic pelvic pain (CPP) is one of the main isthmocele symptoms, together with abnormal uterine bleeding and secondary infertility. When patients undergo a laparoscopic niche repair surgery, it important to determine if they present associated pathologies, such as adenomyosis and/or endometriosis, which are also cause CPP. A retrospective study was performed on 31 CPP undergoing repair. The pre-operative ultrasound analyzed presence adenomyosis. Endometriosis histologically diagnosed....
Abstract Background Forty percent of exploratory laparoscopies are performed for chronic pelvic pain (CPP). However, a final diagnosis is still unreported in 35% the patients. We decided to evaluate identification pathological lesions and improvement painful symptoms patients with CPP normal physical examination imaging who scheduled laparoscopy. The prospective study was designed tertiary referral center endometriosis. Forty-eight complaining laparoscopy were included. Pelvic intensity...
Septate uterus is the most common uterine malformation found in women presenting poor reproductive history. Hysteroscopic septoplasty (HS) restores anatomy a safe procedure.The goal of our study to determine outcomes after HS symptomatic septate uterus.In retrospective observational single centre and complications were evaluated 31 with uterus. The patients separated into two groups according symptoms - infertility or recurrent pregnancy loss (RPL).were live birth rate secondarily...