A5061583107- Advanced biosensing and bioanalysis techniques
- Advanced Biosensing Techniques and Applications
- Molecular Junctions and Nanostructures
- Biosensors and Analytical Detection
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Microbial Metabolic Engineering and Bioproduction
- Force Microscopy Techniques and Applications
- Advanced Nanomaterials in Catalysis
- Neuroscience and Neural Engineering
- Nanofabrication and Lithography Techniques
- Nanowire Synthesis and Applications
- Biofuel production and bioconversion
- RNA Interference and Gene Delivery
- Monoclonal and Polyclonal Antibodies Research
- Analytical Chemistry and Sensors
- Enzyme Catalysis and Immobilization
- Conducting polymers and applications
- Chromium effects and bioremediation
- Adsorption and biosorption for pollutant removal
- Nanoparticle-Based Drug Delivery
- Lipid Membrane Structure and Behavior
- Nanoplatforms for cancer theranostics
- Photosynthetic Processes and Mechanisms
Sogang University
2016-2025
Yonsei University
2022
Seoul Institute
2016
Daewoo Electronics (South Korea)
2007
Northwestern University
2005
Nanoparticle assemblies interconnected with DNA can be used to screen for DNA-binding molecules colorimetrically. The melting temperature of the nanoparticle assembly increases in presence strong-DNA-binding molecules. Thus, strength binding determined by change this sharp transition, which is observable a blue-to-red color (see picture). Supporting information article available on WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z504277_s.pdf or from author. Please note: publisher...
A fluorophore-based bio-barcode amplification assay that relies on in situ detection of fluorophore-labeled barcodes attached to polystyrene (PS) microparticles rather than gold nanoparticles has been developed; the method involves significantly fewer experimental steps and, thus, reduces time for without losing its ultrahigh sensitivity. The fluorescence image shows PS particles, which barcode DNA strands labeled with a fluorophore dye (Alexa 647) have hybridized capture strands.
PSA (prostate-specific antigen) is one of the most widely used proteins for diagnosis breast and prostate cancer. Of note, displays enzymatic activity specific peptide sequence HSSKLQ, which it recognizes cleaves. In this study, we developed a site-specific enzymatic-cleavage-reaction-based biosensor detection using fluorescein isothiocyanate (FITC)/peptide-conjugated gold (Au) nanoparticle complexes (FPANs). The FPANs do not initially fluoresce in spectral region associated with...
Abstract In this study, an electrochemical biosensor composed of a horseradish peroxidase (HRP)-encapsulated protein nanoparticles (HEPNP) was fabricated for the sensitive and selective detection H 2 O . The HEPNP has three-dimensional structure that can contain large amount HRP; therefore, amplify signals necessary Furthermore, reduced graphene oxide (rGO) used to increase efficiency electron transfer from electrode, which could enhance signal. This showed performance with in range 0.01–100...
Silicon nanowires have been used in the development of ultrasensitive biosensors or chemical sensors, which is originated its high surface-to-volume ratio and function as field-effect transistor (FET). In this study, we developed an DNA-gold (Au) nanoparticle complex-modified silicon nanowire field effect (SiNW-FET) biosensor to detect matrix metalloproteinase-2 (MMP-2), has particular interest protein biomarker because relation several important human diseases, through enzymatic cleavage...
Abstract Gold particles have been widely used in the treatment of prostate cancer due to their unique optical properties, such as light-heat conversion response near-infrared radiation. Due well-defined synthesis mechanisms and simple manufacturing methods, gold fabricated various sizes shapes. However, low photothermal transduction efficiency present form is a major obstacle practical therapeutic uses these particles. In current work, we silica-coated nanoparticle cluster address limit...
Enzyme-based electrochemical biosensors have been widely used because of their sensitivity, rapidity, and highly target-specific reactions. However, the immobilized enzymes can hinder electron transfer on surface electrode decrease sensitivity biosensors. To overcome this problem, we synthesized conductive gold nanoclusters with two sets embedded enzyme nanoparticles, which are called nanocluster-embedded dual-enzyme nanoparticles (AuNC-DENPs) composed a glucose oxidase-stabilized...
Hydrogen peroxide (H2O2) has been a fascinating target in various chemical, biological, clinical, and industrial fields. Several types of fluorescent protein-stabilized gold nanoclusters (protein-AuNCs) have developed for sensitive easy detection H2O2. However, its low sensitivity makes is difficult to measure negligible concentrations Therefore, overcome this limitation, we horseradish peroxidase-encapsulated bio-nanoparticle (HEFBNP), comprising bovine serum albumin-stabilized (BSA-AuNCs)...