A5008040226- Endoplasmic Reticulum Stress and Disease
- Mesenchymal stem cell research
- Global Health Care Issues
- Climate Change and Health Impacts
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Ovarian function and disorders
- Saffron Plant Research Studies
- Tryptophan and brain disorders
- COVID-19 Clinical Research Studies
- PI3K/AKT/mTOR signaling in cancer
- Sexual function and dysfunction studies
- Global Cancer Incidence and Screening
- Health and Well-being Studies
- Reproductive Biology and Fertility
- Health disparities and outcomes
- Child and Adolescent Psychosocial and Emotional Development
- Multiple Sclerosis Research Studies
- COVID-19 Impact on Reproduction
- Long-Term Effects of COVID-19
- Infectious Diseases and Mycology
- SARS-CoV-2 and COVID-19 Research
- Actinomycetales infections and treatment
- Pharmacological Receptor Mechanisms and Effects
- Hedgehog Signaling Pathway Studies
Shiraz University of Medical Sciences
2016-2025
Institute for Health Metrics and Evaluation
2024
University of Washington
2024
University of Electronic Science and Technology of China
2023
Tehran University of Medical Sciences
2011-2022
Roozbeh Hospital
2012-2022
Monash University
2022
Isfahan University of Medical Sciences
2019-2021
University of Isfahan
2020
Imam Khomeini Hospital
2016
Since in cell therapy, there are always concerns about immune rejection, genetic disability, and malignancies, special attention has been paid to extracellular vesicles (EVs) which secreted by mesenchymal stem cells (MSCs). In the present study, we assessed compared therapeutic effects of human adipose-derived (hADSC) hADSC-EVs from adipose tissue on experimental autoimmune encephalomyelitis (EAE). After induction EAE C57Bl/6 mice, they were treated with hADSCs, hADSC-EVs, or vehicle...
The mTOR complex 1 (mTORC1) coordinates several important environmental and intracellular cues to control a variety of biological processes, such as cell growth, survival, autophagy, metabolism, in response energy levels, growth signals, nutrients. endoplasmic reticulum (ER) is crucial organelle that essential for numerous cellular functions, including the synthesis, folding, modification newly synthesized proteins, stress responsiveness, maintainence homeostasis. mTOR-mediated upregulation...
Objective To compare the safety and efficacy of bupropion with methylphenidate in children adolescents attention‐deficit/hyperactivity disorder (ADHD). Methods In a 6‐week randomized double‐blind study, 44 patients DSM‐IV‐TR diagnosis ADHD were randomly assigned to receive 100–150 mg/day (100 for <30 kg 150 >30 kg) or 20–30 mg/day. Symptoms assessed using Teacher Parent Attention‐Deficit/Hyperactivity Disorder Rating Scale‐IV (ADHD‐RS‐IV) at baseline weeks 3 6. Results Forty had least...
Oral cancer is a malignant neoplasia that can originate in the oral cavity or lips. It serious global health problem and one of ten most common cancers worldwide. Over years, changes trends oropharyngeal have been observed. The management complicated due to functional cosmetic consequences treating malignancies at these anatomical locations. tumor its treatment affect variety activities, including smell, sight, speaking, respiration, taste, jaw function, mastication, either temporarily...
Polycystic ovary syndrome (PCOS) causes the impairment of female fertility and elevates risk metabolic disorders. The current study aimed to evaluate effects rosmarinic acid (Ros) on ovarian histo-stereology, level reproductive hormones, inflammation in a rat model PCOS. Fifteen adult Sprague Dawley rats were randomly divided into three groups, including controls, PCOS, PCOS+Ros (receiving 25 mg/kg Ros for 39 days). After treatments, inflammatory markers analyzed. PCOS led increased weight...
Objective It has been proposed that a deficit of adenosinergic activity could contribute to the pathophysiology schizophrenia. The authors undertook this study further evaluate level adenosine deaminase (ADA) in patients with chronic schizophrenia treated monotherapy haloperidol, risperidone or clozapine and correlation between ADA response treatment. Methods trial was prospective, 8-week, double blind parallel groups Eligible participants were 51 ages ranging from 20 45 years. All...
CD4+CD25−FoxP3+ cells are a newly recognized subset of T which was first reported in autoimmune diseases. In our previous study, this detected tumor-draining lymph nodes (TDLNs) patients with breast cancer. As little is known about their function TDLNs cancer patients, frequency as well ability to produce interleukin (IL)-2, IL-10, or interferon (IFN)-γ were investigated colorectal (CRC) patients. Mononuclear isolated from 13 CRC using Ficoll-Hypaque gradient centrifugation. Cells stimulated...
Abstract Background Hospital environmental resources have a significant role in cross-transmission of opportunistic pathogens such as actinomycetes species to the patients. Actinomycetes remarkable capability survive adverse and harsh conditions hospital environments; therefore, they are threat health Due this issue, we aimed determine frequency diversity soil, water dust by using combination conventional molecular methods including phenotypic biochemical tests for preliminary identification...