A5084873374- Bipolar Disorder and Treatment
- Health and Well-being Studies
- Obsessive-Compulsive Spectrum Disorders
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Treatment and Access
- Autism Spectrum Disorder Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Suicide and Self-Harm Studies
- Mental Health Research Topics
- Attention Deficit Hyperactivity Disorder
- Schizophrenia research and treatment
- Ophthalmology and Visual Health Research
- Genetics and Neurodevelopmental Disorders
- Electroconvulsive Therapy Studies
- Tryptophan and brain disorders
- Child Nutrition and Feeding Issues
- Eating Disorders and Behaviors
- Treatment of Major Depression
- Pharmacological Effects and Toxicity Studies
- Adolescent Sexual and Reproductive Health
- COVID-19 and Mental Health
- Poisoning and overdose treatments
- Body Image and Dysmorphia Studies
- Sexual function and dysfunction studies
- Homicide, Infanticide, and Child Abuse
Hamedan University of Medical Sciences
2016-2025
Islamic Azad University of Hamedan
2021
Payame Noor University
2021
Universidad San Ignacio de Loyola
2021
Abstract Autism is a neurodevelopmental disorder that causes significant impairment in socialization and communication. It also associated with ritualistic stereotypical behaviour. Recent studies propose both hyper-and hypoglutamatergic ideologies for autism. The objective of this study was to assess the effects memantine plus risperidone treatment children Children autism were randomly allocated or placebo 10-wk, double-blind, placebo-controlled study. dose titrated up 3 mg/d 20 mg/d....
Abstract Introduction: Saffron (Crocus sativus L.) has demonstrated antidepressant effects in clinical studies and extensive anxiolytic experimental animal models. Methods: 66 patients with major depressive disorder accompanied by anxious distress were randomly assigned to receive either saffron (30 mg/day) or citalopram (40 for 6 weeks. Hamilton Rating Scale Depression (HAM-D) Anxiety (HAM-A) used assess treatment effect during the trial. Results: 60 participants finished study. Patients...
Background The antidepressive effect of pioglitazone has been noted in patients with major depressive disorder absence metabolic syndrome. This study was conducted to evaluate the safety and efficacy bipolar depression without concomitant syndrome or diabetes. Method Forty-eight outpatients diagnosis I a episode participated parallel, randomized, double-blind, placebo-controlled trial, 44 underwent 6-week treatment either (30 mg/day) placebo as an adjunctive lithium. Therapeutic serum...
Objectives Recent research has focused on the inflammatory cascade as a key culprit in etiology of bipolar disorder. We hypothesized that celecoxib, via its anti‐inflammatory properties, may have therapeutic role mood Methods Forty‐six inpatients with diagnosis acute mania without psychotic features participated parallel, randomized, double‐blind, placebo‐controlled trial, and underwent six weeks treatment either celecoxib (400 mg daily) or placebo an adjunctive to sodium valproate. Patients...
The role of cholinergic abnormalities in autism was recently evidenced and there is a growing interest modulation, emerging for targeting autistic symptoms. Galantamine an acetylcholinesterase inhibitor allosteric potentiator nicotinic receptors. This study aimed to evaluate the possible effects galantamine as augmentative therapy risperidone, children. In this randomized, double-blind, placebo-controlled, parallel-group study, 40 outpatients aged 4–12 years whom had diagnosis (DSM IV-TR)...
Abstract Multiple sclerosis (MS) is an autoimmune disease in which the immune system attacks nerve cells, resulting neurological disorders. Oxidative stress, free radicals, and neuritis have important roles MS pathogenesis. Here, we aim to evaluate effect of crocin on inflammatory markers, oxidative damage, deoxyribonucleic acid (DNA) damage blood patients with MS. A total 40 were divided into two groups, drug placebo‐treated using random assignment. Participants intervention control groups...
Across the globe, depression is a common psychiatric disorder and main cause of disability among adolescents. To this end, study was conducted to screen for prevalence secondary school female students in city Hamadan, western Iran. In cross-sectional study, total 670 students, within age range 15–18 years were investigated using multistage random sampling method. Moreover, Persian version Center Epidemiologic Studies Depression Scale (CES-D) researcher-designed questionnaire containing...
Aim The aim of the present randomized, double‐blind, placebo‐controlled, 8‐week trial was to assess efficacy and tolerability riluzole augmentation fluvoxamine in treatment patients with moderate severe obsessive–compulsive disorder. Methods Patients were randomized into two parallel groups receive plus placebo or (50 mg twice daily). All patients, regardless their group, received at 100 mg/day for initial 4 weeks study followed by 200 rest course. A total 50 (25 each group) evaluated...
Background: There is growing interest in the identification of novel therapeutic agents for treatment affective disorders, with modafinil being one promising substance. The purpose present investigation was to compare efficacy a combination fluoxetine plus that placebo major depression 6-week double blind and placebo-controlled trial. Methods: Forty-six adult outpatients who met DSM-IV-TR criteria participated Patients had baseline Hamilton Rating Scale score at least 18. were allocated...
Objective. Borderline personality disorder (BPD) is defined as a pervasive pattern of instability in emotion, mood and interpersonal relationships, with comorbidity between PBD depressive disorders (DD). A key competence for successful management relationships emotional intelligence (EI). Given the low EI patients suffering from BPD, present study aimed at investigating effect on both depression training BPD DD. Methods. total 30 inpatients DD (53% females; mean age 24.20 years) took part...
This is an investigation of minocycline efficacy and safety as adjuvant to risperidone in management children with autism.Forty-six diagnosis autistic disorder, according the Diagnostic Statistical Manual Mental Disorders, 4th ed., Text Revision (DSM-IV-TR) criteria a score ≥12 on Aberrant Behavior Checklist-Community (ABC-C) irritability subscale, who were already drug-free for at least 6 months participated randomized controlled trial underwent 10 weeks treatment either (50 mg twice per...
Background: Allopurinol is a drug used to treat hyperuricemia. In patients suffering from acute mania, increased levels of uric acid are observed. A purinergic dysfunction plausibly causative factor in the pathophysiology mania. The aim present study was therefore investigating whether allopurinol has benefits for treated with sodium valproate during Method: double-blind, placebo-controlled lasting 4 weeks, total 50 BPD and mania randomly assigned either treatment (sodium 15 – 20 mg/kg + 300...
Menopausal symptoms are a reproductive health issue for women. Some studies have suggested that the use of probiotics may alleviate severity menopausal and mental status. This study aimed to evaluate effect probiotic administration on improve in postmenopausal women Hamadan, Western Iran. A triple-blind randomized controlled trial was conducted from February 20, 2023, August 23, at Comprehensive Health Service Centers Hamadan City, Participants were intervention control groups. The...
<title>Abstract</title> The full text of this preprint has been withdrawn by the authors due to author disagreement with posting preprint. Therefore, do not wish work be cited as a reference. Questions should directed corresponding author.