A5015828411- Cardiac Arrest and Resuscitation
- COVID-19 diagnosis using AI
- Trauma and Emergency Care Studies
- RNA Research and Splicing
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Respiratory Support and Mechanisms
- Disaster Response and Management
- Cardiac pacing and defibrillation studies
- Genomics and Chromatin Dynamics
- Neuropeptides and Animal Physiology
- Emergency and Acute Care Studies
- Heart Rate Variability and Autonomic Control
- Cardiac electrophysiology and arrhythmias
- Reproductive Biology and Fertility
- Microtubule and mitosis dynamics
- Lung Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Cardiac Imaging and Diagnostics
- Ultrasound in Clinical Applications
- COVID-19 and healthcare impacts
- Neuroscience and Neuropharmacology Research
- Cardiac Health and Mental Health
- Telemedicine and Telehealth Implementation
- Heart Failure Treatment and Management
National Taiwan University Hospital
2016-2025
Baylor Scott & White All Saints Medical Center
2023
Baylor University Medical Center
2023
National Taiwan University
2023
Min Sheng General Hospital
2023
Taipei Veterans General Hospital
2023
University of Liverpool
2020
Aintree University Hospital
2020
National Heart Centre Singapore
2017-2019
Repligen (United States)
2003-2004
Background Frontline health care workers, including physicians, are at high risk of contracting coronavirus disease (COVID-19) owing to their exposure patients suspected having COVID-19. Objective The aim this study was evaluate the benefits and feasibility a double triage telemedicine protocol in improving infection control emergency department (ED). Methods In retrospective study, we recruited aged ≥20 years referred ED National Taiwan University Hospital between March 1 April 30, 2020. A...
In both vertebrates and invertebrates, the expression of several maternal mRNAs is regulated by cytoplasmic polyadenylation. Xenopus oocytes, where most biochemical details this process have been examined, polyadenylation controlled CPEB, a sequence-specific RNA binding protein. The activity which to recruit cleavage specificity factor (CPSF) poly(A) polymerase (PAP) into an active complex, Eg2-catalyzed phosphorylation. Soon after CPEB phosphorylation resulting take place, interaction...
Prompt and correct detection of pulmonary tuberculosis (PTB) is critical in preventing its spread. We aimed to develop a deep learning-based algorithm for detecting PTB on chest X-ray (CXRs) the emergency department. This retrospective study included 3498 CXRs acquired from National Taiwan University Hospital (NTUH). The images were chronologically split into training dataset, NTUH-1519 (images during years 2015 2019; n = 2144), testing NTUH-20 year 2020; 1354). Public databases, including...
CPEB is an mRNA-binding protein that stimulates polyadenylation-induced translation of maternal mRNA once it phosphorylated on Ser 174 or Thr 171 (species-dependent). Disruption the gene in mice causes arrest oogenesis at embryonic day 16.5 (E16.5), when most oocytes are pachytene prophase I. Here, we show undergoes phosphorylation E16.5, but dephosphorylation E18.5, entering diplotene. Although mediated by kinase aurora, due to phosphatase PP1. The temporal control suggests a mechanism...
Abstract Purpose To develop two deep learning-based systems for diagnosing and localizing pneumothorax on portable supine chest X-rays (SCXRs). Methods For this retrospective study, images meeting the following inclusion criteria were included: (1) patient age ≥ 20 years; (2) SCXR; (3) imaging obtained in emergency department or intensive care unit. Included temporally split into training (1571 images, between January 2015 December 2019) testing (1071 2020 to 2020) datasets. All annotated...
The return of spontaneous circulation after cardiac arrest (RACA) score is a well-validated model for estimating the probability (ROSC) in patients with out-of-hospital (OHCA) by incorporating several variables, including gender, age, aetiology, witness status, location, initial rhythms, bystander cardiopulmonary resuscitation (CPR), and emergency medical services (EMS) arrival time. RACA was initially designed comparisons between different EMS systems standardising ROSC rates. End-tidal...
The aim of this study was to validate and compare the performance statistical (Utstein-Based Return Spontaneous Circulation Shockable Rhythm-Witness-Age-pH) machine learning-based (Prehospital Swedish Cardiac Arrest Risk Score) models in predicting outcomes following out-of-hospital cardiac arrest assess impact COVID-19 pandemic on models' performance.
OBJECTIVES: We aimed to develop a computer-aided detection (CAD) system localize and detect the malposition of endotracheal tubes (ETTs) on portable supine chest radiographs (CXRs). DESIGN: This was retrospective diagnostic study. DeepLabv3+ with ResNeSt50 backbone DenseNet121 served as model architecture for segmentation classification tasks, respectively. SETTING: Multicenter PATIENTS: For training dataset, images meeting following inclusion criteria were included: 1) patient age greater...
The 2022 AHA/ACC/HFSA guidelines for the management of heart failure (HF) makes therapeutic recommendations based on HF status. We investigated whether prognosis in-hospital cardiac arrest (IHCA) could be stratified by stage and left ventricular ejection fraction (LVEF).
This study aimed to investigate the association between temporal transitions in heart rhythms during cardiopulmonary resuscitation (CPR) and outcomes after out-of-hospital cardiac arrest.
Abstract Malposition of a nasogastric tube (NGT) can lead to severe complications. We aimed develop computer-aided detection (CAD) system localize NGTs and detect NGT malposition on portable chest X-rays (CXRs). A total 7378 CXRs were retrospectively retrieved from two hospitals between 2015 2020. All annotated with pixel-level labels for localization image-level presence malposition. In the CAD system, DeepLabv3 + backbone ResNeSt50 DenseNet121 served as model architecture segmentation...
Abstract Background New‐onset atrial fibrillation (AF) is associated with an increased risk of stroke in hospitalized patients severe sepsis. Post‐cardiac arrest experience conditions similar to This study investigated whether pre‐arrest AF poor neurological recovery following in‐hospital cardiac (IHCA). Methods single‐centre retrospective included experiencing IHCA between 2005 and 2020. Pre‐arrest electrocardiograms (ECGs) were reviewed, including twelve‐lead ECGs ECG strips. was defined...