A5028490369- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Nanoparticle-Based Drug Delivery
- Analytical Chemistry and Chromatography
- Advancements in Transdermal Drug Delivery
- Analytical Methods in Pharmaceuticals
- RNA Interference and Gene Delivery
- Computational Drug Discovery Methods
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Curcumin's Biomedical Applications
- Immunotherapy and Immune Responses
- Antibiotics Pharmacokinetics and Efficacy
- Protein purification and stability
- Optimal Experimental Design Methods
- Nanoparticles: synthesis and applications
- Lipid Membrane Structure and Behavior
- Crystallization and Solubility Studies
- Pharmacological Effects of Natural Compounds
- Pesticide Residue Analysis and Safety
- Nigella sativa pharmacological applications
- Essential Oils and Antimicrobial Activity
- Dermatology and Skin Diseases
- Advanced biosensing and bioanalysis techniques
- Dendrimers and Hyperbranched Polymers
Jamia Hamdard
2013-2024
University of Central Lancashire
2021-2024
American Pharmacists Association
2024
Panjab University
2012-2022
Sam Higginbottom Institute of Agriculture
2021-2022
Delhi Pharmaceutical Science and Research University
2022
Jubilant Life Sciences (India)
2015-2019
King Khalid University
2019
Roland Institute of Pharmaceutical Sciences
2012-2018
Chandigarh University
2016-2017
Many synthetic drugs reported to be used for the treatment of inflammatory disorders are least interest now a days due their potential side effects and serious adverse as they found highly unsafe human assistance. Since last few decades, herbal have regained popularity in against several ailments. Herbals containing anti-inflammatory activity (AIA) topics immense absence problems them, which associated with preparations. The primary objective this review is provide deep overview recently...
Of late, solid self-nanoemulsifying drug delivery systems (S-SNEDDS) have been extensively sought-after owing to their superior portability, loading, stability and patient compliance. The current studies, therefore, entail systematic development, optimization evaluation (in vitro, in situ vivo) of the formulations (SNEDDS) lovastatin employing rational quality by design (QbD)-based approach formulation (FbD). patient-centric target product profile (QTPP) critical attributes (CQAs) were...
The present work describes the development of poly(lactic co-glycolic acid) (PLGA) nanoparticles (NPs) rutin (RT) for treatment hepatocellular carcinoma in rats.RT-loaded PLGA NPs (RT-PLGA-NPs) were prepared by double emulsion evaporation method. Further these are optimized Box-Behnken design. evaluated size, polydispersity index, drug-loading capacity, entrapment, gastric stability, vitro drug release, vivo preclinical studies and biochemical studies.Preclinical evaluation RT-PLGA-NPs...
The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations methoxsalen enhanced topical delivery effective treatment against vitiligo. ethosomes were prepared by central composite design (CCD) characterized various quality attributes like vesicle shape, size, zeta potential, lamellarity, drug entrapment leaching. optimized subsequently incorporated int Carbopol® 934 gel content, rheological behavior, texture profile, in vitro release, ex...
Topical delivery of local anesthetics has been an area interest for researchers considering the barrier properties skin and unfavorable physicochemical drugs. In present study, efforts have made to modify in vivo efficacy eutectic mixture lidocaine prilocaine by exploiting phospholipid modified microemulsion based systems. The strategic QbD (D-optimal design) enabled systematic optimization approach, after having obtained isotropic ternary phase diagram, resulted into system with most...
The current studies entail Quality by Design (QbD)-enabled development of a simple, rapid, sensitive and cost-effective high-performance liquid chromatographic method for estimation tamoxifen citrate (TMx). factor screening were performed using 7-factor 8-run Taguchi design. Systematic optimization was employing Box-Behnken design selecting the mobile phase ratio, buffer pH oven temperature as critical parameters (CMPs) identified from studies, thus evaluating analytical attributes (CAAs),...
The present work describes the systematic development of paclitaxel and naringenin-loaded solid lipid nanoparticles (SLNs) for treatment glioblastoma multiforme (GBM). So far only temozolomide therapy is available GBM treatment, which fails by large amount due to poor brain permeability drug recurrent metastasis tumor. Thus, we investigated combination containing naringenin GBM, as these drugs have individually demonstrated significant potential management a wide variety carcinoma. A product...
This work aimed to develop dual drug-loaded nanostructured lipid carriers of raloxifene and naringin (RLX/NRG NLCs) for breast cancer. RLX/NRG NLCs were prepared using Compritol 888 ATO oleic acid a hot homogenization-sonication method optimized central composite design (CCD). The characterized evaluated multiple technological means. exhibited particle size 137.12 nm, polydispersity index (PDI) 0.266, zeta potential (ZP) 25.9 mV, entrapment efficiency (EE) 91.05% (raloxifene) 85.07%...