A5061002569- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Analytical Chemistry and Chromatography
- Advancements in Transdermal Drug Delivery
- Analytical Methods in Pharmaceuticals
- Nanoparticle-Based Drug Delivery
- Computational Drug Discovery Methods
- RNA Interference and Gene Delivery
- Dermatology and Skin Diseases
- Drug Transport and Resistance Mechanisms
- Graphene and Nanomaterials Applications
- Estrogen and related hormone effects
- Mangiferin and Mango Extracts
- Lipid Membrane Structure and Behavior
- Protein purification and stability
- Synthesis and biological activity
- Antibiotics Pharmacokinetics and Efficacy
- Fullerene Chemistry and Applications
- Carbon Nanotubes in Composites
- Nanoplatforms for cancer theranostics
- Pharmacological Effects of Natural Compounds
- Crystallization and Solubility Studies
- Pesticide Residue Analysis and Safety
- Pharmaceutical studies and practices
- Antifungal resistance and susceptibility
Rutgers, The State University of New Jersey
2025
Panjab University
2015-2024
Dayanand Medical College & Hospital
2024
Penn State Milton S. Hershey Medical Center
2024
Queens Hospital Center
2024
Icahn School of Medicine at Mount Sinai
2024
Mount Sinai Queens
2024
University College of Medical Sciences
2024
Chitkara University
2005-2024
Government Medical College, Amritsar
2024
Of late, solid self-nanoemulsifying drug delivery systems (S-SNEDDS) have been extensively sought-after owing to their superior portability, loading, stability and patient compliance. The current studies, therefore, entail systematic development, optimization evaluation (in vitro, in situ vivo) of the formulations (SNEDDS) lovastatin employing rational quality by design (QbD)-based approach formulation (FbD). patient-centric target product profile (QTPP) critical attributes (CQAs) were...
The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations methoxsalen enhanced topical delivery effective treatment against vitiligo. ethosomes were prepared by central composite design (CCD) characterized various quality attributes like vesicle shape, size, zeta potential, lamellarity, drug entrapment leaching. optimized subsequently incorporated int Carbopol® 934 gel content, rheological behavior, texture profile, in vitro release, ex...
Topical delivery of local anesthetics has been an area interest for researchers considering the barrier properties skin and unfavorable physicochemical drugs. In present study, efforts have made to modify in vivo efficacy eutectic mixture lidocaine prilocaine by exploiting phospholipid modified microemulsion based systems. The strategic QbD (D-optimal design) enabled systematic optimization approach, after having obtained isotropic ternary phase diagram, resulted into system with most...
The current studies entail Quality by Design (QbD)-enabled development of a simple, rapid, sensitive and cost-effective high-performance liquid chromatographic method for estimation tamoxifen citrate (TMx). factor screening were performed using 7-factor 8-run Taguchi design. Systematic optimization was employing Box-Behnken design selecting the mobile phase ratio, buffer pH oven temperature as critical parameters (CMPs) identified from studies, thus evaluating analytical attributes (CAAs),...
Buccoadhesives have long been employed to improve the bioavailability of drugs undergoing significant hepatic first-pass metabolism. Diltiazem hydrochloride (DLZ) is also reported low oral due an extensive effect. Controlled-release buccoadhesive hydrophilic matrices containing DLZ were prepared using a 32 factorial design. Amounts Carbopol® 934P (CP) and Methocel® K100LV (HPMC) taken as formulation variables (factors) for optimizing bioadhesion, kinetics dissolution diffusion. A...
Carvedilol, a widely prescribed cardiovascular drug for hypertension and congestive heart failure, exhibits low variable bioavailability owing to poor absorption extensive hepatic first-pass metabolism. The current research work, therefore, entails formulation development of liquid self-nano-emulsifying delivery systems (SNEDDS) enhance the carvedilol by facilitating its transport via lymphatic circulation. constituents, i.e. lipids, surfactants, co-surfactants, were selected on basis...
This work was intended to investigate the targeting potential of fructose-tethered lipid-polymeric hybrid nanoparticles (F-BC-MTX-LPHNPs) co-loaded with beta carotene (BC) and methotrexate (MTX) in breast cancer therapeutics find out possible protective role BC on MTX-induced toxicity.F-BC-MTX-LPHNPs were fabricated using self-assembled nano-precipitation technique. Fructose conjugated surface particles. The vitro cytotoxicity, sub-cellular localization apoptotic activity F-BC-MTX-LPHNPs...