A5042454040- Gut microbiota and health
- Metabolism, Diabetes, and Cancer
- Helicobacter pylori-related gastroenterology studies
- Liver Disease Diagnosis and Treatment
- Agriculture, Soil, Plant Science
- Natural Products and Biological Research
- Epigenetics and DNA Methylation
- Nutrition, Genetics, and Disease
- Alcohol Consumption and Health Effects
- Phytochemicals and Antioxidant Activities
- Biofuel production and bioconversion
- PI3K/AKT/mTOR signaling in cancer
- IL-33, ST2, and ILC Pathways
- Genomics, phytochemicals, and oxidative stress
- Asthma and respiratory diseases
- Ruminant Nutrition and Digestive Physiology
- Atherosclerosis and Cardiovascular Diseases
- Antioxidant Activity and Oxidative Stress
- Turfgrass Adaptation and Management
- Plant and fungal interactions
- Fungal Biology and Applications
- Nutritional Studies and Diet
- Polysaccharides and Plant Cell Walls
- Seed and Plant Biochemistry
- Nuts composition and effects
Nanjing Forestry University
2025
First Affiliated Hospital of Zhengzhou University
2024-2025
FH Aachen
2024-2025
Beijing Normal University - Hong Kong Baptist University United International College
2024
Central South University of Forestry and Technology
2017-2024
Central South University
2017-2024
Shanxi Medical University
2020-2024
Institute of Food Science & Technology
2021
Qinghai Provincial Peoples Hospital
2021
Octacosanol has multiple biological functions. In this study, the anti-inflammatory effect and molecular mechanism of octacosanol were evaluated by using dextran sulfate sodium (DSS)-induced ulcerative colitis model in mice lipopolysaccharide (LPS)-stimulated mouse macrophage RAW264.7 cells. The was induced 3.0% DSS 8-week ICR orally administered with 100 mg/kg/day. results showed that significantly improved health status reduced DSS-induced pathological damage colonic tissues. obviously...
A high fat and cholesterol diet (HFCD) can modulate the gut microbiota, which is closely related with hypercholesterolemia. This study aimed to explore anti-hypercholesterolemia effect of oryzanol, investigate whether function oryzanol associated microbiota metabolites. 16S rRNA ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry were applied for untargeted metabolomics, respectively. The results showed that HFCD significantly upregulated body accumulation...
Brown rice (BR) is a traditional health food being rich in various active substances, which have effective preventive and therapeutic effects on many diseases. In this review, we systemically summarized the efficacy of BR cardiovascular diseases (CVDs), hyperlipidemia, hypertension, diabetes, obesity, osteoporosis, neurodegenerative diseases, cancer, immune disorders, inflammation, anxiety, liver stomach damage, etc. Underlying mechanisms also been analyzed, include regulating lipid...
Alcoholic liver disease (ALD) is primarily caused by long-term excessive alcohol consumption. Cyanidin-3-O-glucoside (C3G) a widely occurring natural anthocyanin with multiple biological activities. This study aims to investigate the effects of C3G isolated from black rice on ALD and explore potential mechanism. C57BL/6J mice (male) were fed standard diet (CON) Lieber-DeCarli liquid-fed (Eth) or supplemented 100 mg/kg/d Diet (Eth-C3G), respectively. Our results showed that could effectively...
Hyperlipidemia is intricately associated with the dysregulation of gut microbiota and host metabolomes. This study explored antihyperlipidemic function oryzanol investigated whether affected microbiome its related metabolites. Hamsters were fed a standard diet (Control) high fat cholesterol (HFCD) or without oryzanol, separately. Our results showed that significantly decreased HFCD-induced accumulation, serum total cholesterol, low-density lipoprotein (LDL-c), LDL-c/HDL-c ratio,...
δ-Tocotrienol, an important component of vitamin E, has been reported to possess some physiological functions, such as anticancer and anti-inflammation, however their molecular mechanisms are not clear. In this study, δ-tocotrienol was isolated purified from rice bran. The anti-inflammatory effect mechanism against lipopolysaccharides (LPS) activated pro-inflammatory mediator expressions in RAW264.7 cells were investigated. Results showed that significantly inhibited LPS-stimulated nitric...
Several publications report that octacosanol (OCT) has different biological functions. This study was designed to evaluate the antifatigue effect and molecular mechanism of (200 mg/(kg day)) in forced exercise-induced fatigue models trained male C57BL/6 mice. Results showed ameliorated mice's autonomic activities, forelimb grip strength, swimming endurance, levels liver glycogen (LG), muscle (MG), blood lactic acid (BLA), lactate dehydrogenase (LDH), superoxide dismutase (SOD), glutathione...
Edible bird's nest is a natural food tonic and thought to be many health benefits. Sialic acid the main bioactive component contributing biological activity of edible nest. This study aimed clarify effect mechanism sialic on ulcerative colitis through dextran sulfate sodium induced model lipopolysaccharide stimulated RAW264.7 cell inflammation. The results revealed that significantly reduced inflammation MAPK phosphorylation in vivo. In vitro, markedly inhibited productions pro-inflammatory...
The increasing demand for bio-based chemicals and sustainable materials has placed biomass-derived lactic acid in the spotlight as a key building block biodegradable polylactic (PLA). Perennial ryegrass (Lolium perenne) is promising feedstock due to its high dry matter (DM) yield, adaptability, widespread agricultural use. This study investigates an integrated acid–silage cascade process, focusing on how pH regulation, harvest timing, biomass characteristics influence production...
The effects of plant configuration modes on soil organic carbon fractions are mainly reflected in species, root structure, apoplastic input, and microbial activity, different affect the accumulation stability by changing input decomposition processes matter. Considering common use local species ecological restoration their diverse functions, we selected five lakeshore zone Hongze Lake (Metasequoia glyptostroboides-Amorpha fruticosa L. (M-Af), Metasequoia glyptostroboides-Acorus calamus...
The incidence of obesity has increased significantly on account the alterations living habits, especially changes in eating habits. In this study, we investigated effect octacosanol lipid lowering and its molecular mechanism. High-fat diet (HFD)-induced mouse model was used study. Thirty C57BL/6J mice were divided into control, HFD, HFD+Oct groups randomly, every group included ten mice. intragastrically administrated 100 mg/kg/day octacosanol. After 10 weeks for treatment, our results...
Perennial ryegrass (Lolium perenne) is an underutilized lignocellulosic biomass that has several benefits such as high availability, renewability, and yield. The grass press-juice obtained from the mechanical pretreatment can be used for bio-based production of chemicals. Lactic acid a platform chemical attracted consideration due to broad area applications. For this reason, more sustainable lactic expected increase. In work, was produced using complex medium at bench- reactor scale, results...
The increasing demand for bio-based chemicals and sustainable materials has placed biomass-derived lactic acid in the spotlight as a key building block biodegradable polylactic (PLA). Perennial ryegrass (Lolium perenne) is promising feedstock due to its high dry matter (DM) yield, adaptability, widespread agricultural use. This study investigates an integrated acid–silage cascade process, focusing on how pH regulation, harvest timing, biomass characteristics influence production while...
This study evaluates Lolium perenne press juice as a sustainable substrate for Single-Cell Protein (SCP) production using Kluyveromyces marxianus. Key fermentation parameters were systematically optimized, including microbial reduction, dilution ratios, temperature, and nutrient supplementation. Pasteurization at 75 °C preserved essential nutrients better than autoclaving, resulting in 27.8% increase biomass yield. A 1:2 of enhanced efficiency, achieving 20.2% higher despite lower initial...
This study evaluated Lolium perenne press juice as a sustainable substrate for Single-Cell Protein (SCP) production using Kluyveromyces marxianus. Key fermentation parameters were systematically optimized, including microbial reduction, dilution ratios, temperature, and nutrient supplementation. Pasteurization at 75 °C preserved essential nutrients better than autoclaving, resulting in 27.8% increase biomass yield. A 1:2 of enhanced efficiency, achieving 20.2% higher despite lower initial...
Studies have shown that the peroxidation caused by oxygen free radicals is an important reason of vascular endothelial dysfunction and multiple diseases. In this study, active peptides (F2ds) were isolated from fermentation product rice dregs its antioxidant effects approved. Human umbilical vein cells (HUVECs) stimulated H 2 O used to evaluate antioxidation effect molecular mechanism in oxidative stress model. F2d protected ‐induced damage HUVECs a dosage‐dependent manner. can reduce...