- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Sports injuries and prevention
- Osteoarthritis Treatment and Mechanisms
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Musculoskeletal synovial abnormalities and treatments
- Shoulder Injury and Treatment
- Medical and Biological Sciences
- Traumatic Brain Injury Research
- Reliability and Agreement in Measurement
- Delphi Technique in Research
- Radiology practices and education
- Aortic aneurysm repair treatments
- Protease and Inhibitor Mechanisms
- Psychometric Methodologies and Testing
- Atrial Fibrillation Management and Outcomes
- Spine and Intervertebral Disc Pathology
- Connective tissue disorders research
- Bone and Joint Diseases
- Bone fractures and treatments
- Infrared Thermography in Medicine
Erasmus University Rotterdam
2010-2022
Erasmus MC
2013-2022
St. Antonius Ziekenhuis
2021
Medisch Centrum Haaglanden
2016-2019
Aneurysms-osteoarthritis syndrome (AOS) is a new autosomal dominant syndromic form of thoracic aortic aneurysms and dissections characterised by the presence arterial tortuosity, mild craniofacial, skeletal cutaneous anomalies, early-onset osteoarthritis. AOS caused mutations in SMAD3 gene.A cohort 393 patients with without mutation FBN1, TGFBR1 TGFBR2 was screened for SMAD3. The originated from Netherlands, Belgium, Switzerland USA. clinical phenotype total 45 eight different families...
The goal of the OPTIKNEE consensus is to improve knee and overall health, prevent osteoarthritis (OA) after a traumatic injury. followed seven-step hybrid process. Expert groups conducted 7 systematic reviews synthesise current evidence inform recommendations on burden injuries; risk factors for post-traumatic OA; rehabilitation patient-reported outcomes, muscle function functional performance tests monitor people at OA. Draft definitions, clinical research were generated, iteratively...
Anterior cruciate ligament (ACL) rupture is a well-known risk factor for development of knee osteoarthritis. Early identification those patients at and early the process ACL leading to osteoarthritis may aid in preventing onset or progression osteoarthritis.To identify degenerative changes as assessed on magnetic resonance imaging (MRI) after 2-year follow-up with recent evaluate which determinants are related these changes.Cohort study; Level evidence, 2.Included this study were 154 adults...
We have investigated whether shape of the knee can predict clinical outcome patients after an anterior cruciate ligament rupture. used statistical modelling to measure joint 182 prospectively followed on lateral and Rosenberg view radiographs a rupture ligament. Subsequently, we associated with International Knee Documentation Committee subjective score at two years follow-up. The mean age was 31 (21 51), majority were male (n = 121) treated operatively 135). found modes (shape variations)...
Background: Semitendinosus and gracilis tendons may regenerate after harvesting for ligament reconstruction procedures. However, predictive factors of tendon regeneration the extent functional recovery remain unclear. Purpose: To identify hamstring to examine morbidity nonregenerated tendons. Study Design: Cohort study; Level evidence, 3. Methods: Of 154 patients who were included in a prospective follow-up study, 79 underwent anterior cruciate entailing met following inclusion criteria: (1)...
Abstract Background Early diagnosis of knee osteoarthritis (OA) is important in managing this disease, but such an early diagnostic tool still lacking clinical practice. The purpose study was to develop models for stage OA based on the first 2-year course after patient’s initial presentation primary care and identify whether these factors had additive discriminative value over baseline factors. Methods We extracted eligible patients’ radiographic data from CHECK cohort formed according...
Objective: Anterior cruciate ligament (ACL) injury prevention programs could be more effective if we select patients at risk for sustaining an ACL rupture. The purpose of this study is to identify radiographic shape variants the knee between with and without Methods: We compared lateral Rosenberg view X-rays 168 prospectively followed a ruptured control group intact ACLs, matched gender, after trauma. used statistical modeling software examine find differences in both groups. Results: In...
Abstract Multiple studies found hamstring tendon (HT) autograft diameter to be a risk factor for anterior cruciate ligament (ACL) reconstruction failure. This study aimed determine which preoperative measurements are associated with HT in ACL by directly comparing patient characteristics and cross-sectional area (CSA) measurement of the semitendinosus gracilis on magnetic resonance imaging (MRI). Fifty-three patients primary four-stranded were included this study. Preoperatively we recorded...
Osteophytes, also small ones, are an important imaging feature of OA. However, due to their high prevalence on MR, the question has arisen whether these truly pathophysiologic features early OA, a result physiologic aging, or rather merely transient phenomenon. The aim this study was explore osteophytes MR in various locations knee, with special emphasis osteophytes, across multiple large studies conducted our institution comprising wide range subjects at different ages. Retrospective...
Abstract Purpose “Biologic therapies” in the field of orthopaedic surgery and sports medicine, so called orthobiologics, have been gaining significant interest from physicians patients, with increasing usage over recent years. The aim this study is to (1) evaluate orthobiologics Netherlands, (2) clarify reasons for use or non-use (3) most addressed disease orthobiologics. Methods authors created a 19-quenstion online survey comprised both closed-ended open-ended response questions order...
To identify highly ranked features related to clinicians' diagnosis of clinically relevant knee OA.General practitioners (GPs) and secondary care physicians (SPs) were recruited evaluate 5-10 years follow-up clinical radiographic data knees from the CHECK cohort for presence OA. GPs SPs gathered in pairs; each pair consisted one GP SP, paired clinicians independently evaluated same subset knees. A was made by SP before after viewing data. Nested 5-fold cross-validation enhanced random forest...