A5025749203- Antimicrobial Resistance in Staphylococcus
- Psoriasis: Treatment and Pathogenesis
- Bacterial biofilms and quorum sensing
- Streptococcal Infections and Treatments
- Superconducting Materials and Applications
- Asthma and respiratory diseases
- Genetic and rare skin diseases.
- Inflammasome and immune disorders
- Skin and Cellular Biology Research
- Physics of Superconductivity and Magnetism
- MicroRNA in disease regulation
- Porphyrin Metabolism and Disorders
- Click Chemistry and Applications
- Acne and Rosacea Treatments and Effects
- Frequency Control in Power Systems
- Hair Growth and Disorders
- RNA regulation and disease
- Circular RNAs in diseases
- Heme Oxygenase-1 and Carbon Monoxide
- T-cell and B-cell Immunology
- Gout, Hyperuricemia, Uric Acid
- Biotin and Related Studies
- Magnetic Properties and Applications
- Wnt/β-catenin signaling in development and cancer
- Bacterial Identification and Susceptibility Testing
First Affiliated Hospital of Gannan Medical University
2017-2025
Anhui Medical University
2014-2015
Ministry of Education of the People's Republic of China
2014
Tsinghua University
2013-2014
Huashan Hospital
2014
Fudan University
2014
Abstract Genome-wide association studies (GWASs) have reproducibly associated ∼40 susceptibility loci with psoriasis. However, the missing heritability is evident and contributions of coding variants not yet been systematically evaluated. Here, we present a large-scale whole-exome array analysis for psoriasis consisting 42,760 individuals. We discover 16 SNPs within 15 new genes/loci psoriasis, including C1orf141 , ZNF683 TMC6 AIM2 IL1RL1 CASR SON ZFYVE16 MTHFR CCDC129 ZNF143 AP5B1 SYNE2...
High temperature superconducting (HTS) armature windings have the potential for increasing electric loading of a synchronous generator due to their high current transport capacity, which could increase power density an HTS rotating machine. In this work, novel prototype with stator and permanent magnet rotor has been developed. It basic structure four poles six slots. The winding was constructed from double-pancake race-track coils 44 turns each. designed deliver 2.5 kW at 300 rpm. A...
<h3>Background</h3> Disseminated superficial actinic porokeratosis (DSAP) is a rare autosomal dominant genodermatosis characterised by annular lesions that has an atrophic centre and prominent peripheral ridge distributed on sun exposed area. It exhibits high heterogeneity, five linkage loci have been reported. The mevalonate kinase (<i>MVK</i>) gene located 12q24 confirmed as one of the disease-causing genes. But, pathogenesis large part DSAP remains unclear so far. <h3>Methods</h3>...
Dystrophic epidermolysis bullosa (DEB) is a heterogeneous and rare genetic skin disease caused by mutations in the COL7A1 gene, which encodes Type VII collagen. The absence or dysfunction of collagen can cause dense lower layer basal membrane zone to separate from dermis, leading blister formation various complications. In different DEB subtypes, severity phenotype associated, some extent, with outcome may be reduced expression, remarkably reduced, completely absent. Here, we report case...
This study compared the clinical effectiveness of two methods platelet-rich plasma (PRP) administration for treating androgenetic alopecia (AGA): microneedle delivery and intradermal injection. The also evaluated adverse reactions associated with both methods. Twenty patients AGA were selected according to specific inclusion exclusion criteria. scalp each patient was divided into treatment areas along midline, randomly assigned receive PRP either via injection (n = 20) or 20). comprised...
Gasdermin (GSDM) B is a member of the GSDM family, which protein that may be involved in cell pyroptosis process and associated with inflammatory diseases.
We investigated the influence of amoxicillin pre-exposure on treatment outcomes, Chlamydia trachomatis (CT) culture, presence drug-resistant genes, minimum inhibitory concentrations (MICs), and fractional (FICs) in CT clinical strains. Additionally, we explored effect different antimicrobial combinations CT.Clinical data 62 patients with infection were recorded. Of these, 33 had to 29 did not. Among pre-exposure, 17 received azithromycin 16 minocycline. without 15 14 All underwent...
Objective: To analyze the antibiotic resistance profile, virulence genes, and molecular typing of Staphylococcus aureus ( S. ) strains isolated in skin soft tissue infections at First Affiliated Hospital, Gannan Medical University, to better understand epidemiological characteristics . Methods: In 2023, 65 were from patients with infections. Strain identification susceptibility tests performed using VITEK 2 gram-positive bacteria cards. DNA was extracted a extraction kit, all genes amplified...
Staphylococcal Scalded Skin Syndrome (SSSS) is caused by a special type of Staphylococcus aureus (S.aureus) which can produce exfoliative toxins. The generalized SSSS recommended to be admitted and treated with intravenous antibiotics. However, there were limited reports on whether personal clinical factors have impacts the duration antibiotic application for pediatric patients SSSS. We performed study assess affecting treatment course patients. Additionally, positive culture rates S.aureus...
To compare treatment duration, influencing factors, and costs among intravenous antibiotic groups combined with 2% mupirocin ointment for treating staphylococcal scalded skin syndrome (SSSS).
Researchers have learned that nearly all conditions and diseases a genetic component. With the benefit of technological advances, many single-nucleotide polymorphisms (SNPs) been found to be associated with risk complex disorders by using genome wide association studies (GWASs). Disease-associated SNPs are sometimes shared healthy controls cannot clearly distinguish affected individuals from unaffected ones. The combined effects multiple independent contribute disease process, but revealing...
Abstract Aim Staphylococcus aureus has become a common pathogen that causes hospital-acquired infections. This study aimed to investigate the drug resistance and virulence genes ( mupA , fnbA arcA PVL TSST mecA ermC ermA ) of from infectious patients in tertiary hospital China. Moreover, levels these erythromycin-resistant isolates were performed. Methods From 2020 2022, 58 strains isolated with clinical infection collected, strain identification susceptibility tests performed by using VITEK...
Incontinentia pigmenti (IP), an X-chromosome dominant genodermatosis caused by mutations in the
Abstract Background: Staphylococcal Scalded Skin Syndrome (SSSS) is caused by a special type of Staphylococcus aureus (S.aureus) which can produce exfoliative toxins. The generalized SSSS recommended to be admitted and treated with intravenous antibiotics. However, there were limited reports on whether personal clinical factors have impacts the duration antibiotic application for pediatric patients SSSS.We performed study assess affecting treatment course patients. Additionally, positive...