A5029133281- Isotope Analysis in Ecology
- Mass Spectrometry Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Microbial Natural Products and Biosynthesis
- Analytical Chemistry and Chromatography
- Atmospheric chemistry and aerosols
- Petroleum Processing and Analysis
- Analytical chemistry methods development
- Carbohydrate Chemistry and Synthesis
- Air Quality and Health Impacts
- Marine and coastal ecosystems
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Thermochemical Biomass Conversion Processes
- Climate change and permafrost
- Chemical Synthesis and Analysis
- Methane Hydrates and Related Phenomena
- Radioactive contamination and transfer
- Advanced Chemical Sensor Technologies
- Chemical Reactions and Isotopes
- Hydrocarbon exploration and reservoir analysis
- Fungal Biology and Applications
- Atmospheric Ozone and Climate
- Lignin and Wood Chemistry
- Radioactivity and Radon Measurements
University of Cambridge
2024-2025
Skolkovo Institute of Science and Technology
2016-2024
Ben-Gurion University of the Negev
2023
Lomonosov Moscow State University
2014-2021
Institute of Energy Problems of Chemical Physics
2016-2019
Moscow State University
2019
The objectives of this study were to identify molecular features characteristic arctic DOM from the Kolyma River basin and elucidate structural imprints induced by a choice sorption technique. To achieve goal, was isolated with use three nonionic sorbents: Amberlite XAD-8 resin, PPL- C18 - SPE cartridges, one anion exchanging resin-diethylaminoethyl (DEAE) -cellulose. studies conducted electrospray ionization Fourier Transform Ion Cyclotron Resonance (ESI FT-ICR) mass spectrometry liquid...
The goal of this study was to establish a relationship between the optical properties soil dissolved organic matter (DOM) and acidic functions carried out by its individual constituents. We obtained 12 fractions DOM samples using sequential solid phase extraction on nonionic sorbent at steadily lowered pH values: 7, 5, 3, 2, which correspond low bounds pKa values phenols, aliphatic, aromatic carboxylic acids, ketoacids. structural studies were conducted with use NMR selective...
The exact structural formulas of model humic substances are identified using controllable H/D exchanged coupled to FTMS.
We report a novel family of natural lipoglycopeptides produced by Streptomyces sp. INA-Ac-5812. Two major components the mixture, named gausemycins A and B, were isolated, their structures elucidated. The compounds are cyclic peptides with unique peptide core several remarkable structural features, including unusual positions d-amino acids, lack Ca2+ -binding Asp-X-Asp-Gly (DXDG) motif, tyrosine glycosylation arabinose, presence 2-amino-4-hydroxy-4-phenylbutyric acid (Ahpb) chlorinated...
H/D exchange coupled with high-resolution mass spectrometry has become a powerful analytical approach for structural investigations of complex organic matrices.
// Elena I. Fedoros 1, 5 , Alexey A. Orlov 2 Alexander Zherebker 2, 8 Ekaterina Gubareva 1 Mikhail Maydin Andrey Konstantinov Konstantin Krasnov 3 Ruben N. Karapetian 4 Izotova Sergey E. Pigarev V. Panchenko Margarita L. Tyndyk Dmitry Osolodkin 6, 7 Evgeny Nikolaev 8, 9, 10 Irina Perminova and Vladimir Anisimov N.N. Petrov National Medical Research Center of Oncology, Saint-Petersburg 197758, Russia Department Chemistry, Lomonosov Moscow State University, 119991, Institute Toxicology,...
Natural organic matter (NOM) components measured with ultrahigh-resolution mass spectrometry (UHRMS) are often assessed by molecular formula-based indices, particularly related to their aromaticity, which further used as proxies explain biogeochemical reactivity. An aromaticity index (AI) is calculated mostly respect carboxylic groups abundant in NOM. Here, we propose a new constrained AIcon based on the distribution of among individual NOM obtained deuteromethylation and UHRMS. Applied...
Abstract Humic substances (HS) are complex natural mixtures comprising a large variety of compounds produced during decomposition decaying biomass. The molecular composition HS is extremely diverse as it was demonstrated with the use high resolution mass spectrometry. building blocks mostly represented by plant-derived biomolecules (lignins, lipids, tannins, carbohydrates, etc.). As result, show wide spectrum biological activity. Despite that, remain ‘biological activity black-box’ due to...
The objective of this study was to shed light on structural features which underlay intensity long wave absorbance natural organic matter (NOM) using 1H NMR spectroscopy. For purpose, a set the NOM samples assembled from arctic and nonarctic sampling sites (the Kolyma river basin Moscow region, respectively). It ensure substantial difference in humification degree isolated matter—the biogeochemical proxy long-wave NOM. analyzed solution-state distribution both backbone exchangeable protons...
Abstract The Ob-Irtysh River system is the seventh-longest one in world. Unlike other Great Siberian rivers, it only slightly impacted by continuous permafrost its low flow. Instead, drains Vasyugan mire, which world largest swamp, and receives huge load of Irtysh waters drain populated lowlands East Plain. central challenge this paper to understand processes responsible for molecular transformations natural organic matter (NOM) river along South-North transect. For solving task, NOM was...
The aim of this study was to examine the hepatoprotective activity multicomponent mixtures natural origin in BALB/C mouse model, with subacute liver failure (SALF) induced by administration toxin carbon tetrachloride (CCl4). activated hydrolytic lignin (BP-Cx-1), humic acid peloids (HA), and isoflavones from kudzu Pueraria lobata roots (IFL) evaluated using mass spectrometry (MS)-based omics technologies. Our MS-based approach revealed new insights into molecular mechanisms origin....
The health effects of particulate matter (PM) are well-documented, with long-term exposure to elevated concentrations respirable PM linked increased risks respiratory conditions such as allergic reactions, lung inflammation, and asthma. A key contributor these is the oxidative stress induced by PM, stemming from heavy metals generation reactive oxygen species (ROS).In this study, we measured potential (OP) dust inhalable collected households in Slovenia, Sweden, UK part international INQUIRE...
Abstract. This paper presents the results of three weeks aerosol sampling at Henties Bay coastal site in Namibia during Aerosols, Radiation and Clouds southern Africa (AEROCLO-sA) field campaign August–September 2017. The coincided with a transition period between two synoptic regimes corresponded to significant change composition measured particular that mineral dust. During August, dust was natural windblown from southerly gravel plains consistent previously observed Namibia. In September,...
Abstract. In order to study aerosols in environments influenced by anthropogenic and biogenic emissions variable extents, PM1 samples were collected during summer 2022 the greater Paris area (ACROSS campaign, Atmospheric Chemistry Of Suburban Forest, 14 June 25 July) at two locations that represent urban suburban forested areas. They analyzed using high-resolution mass spectrometry (HRMS) together with total carbon (TC) a thermo-optical method. Both sites are compared here explore...
The aim of this study was to examine the hepatoprotective activity multicomponent mixtures natural origin in BALB/C mouse model (59 female mice), with non-alcoholic fatty liver disease (NAFLD) induced by administration streptozotocin (STZ) combination a high-fat, high-fructose diet. activated hydrolytic lignin (BP-Cx-1), metanolic fraction BP-Cx-1 (BP-Cx-M) and isoflavones from kudzu Pueraria lobata roots (IFL) evaluated using mass spectrometry (MS)-based omics technologies. Untargeted...