María Clara Yépez Chamorro
A5080085424- Global Cancer Incidence and Screening
- Essential Oils and Antimicrobial Activity
- Morinda citrifolia extract uses
- Data Mining Algorithms and Applications
- Public Health and Social Inequalities
- Cervical Cancer and HPV Research
- Glioma Diagnosis and Treatment
- Global Public Health Policies and Epidemiology
- Colorectal Cancer Screening and Detection
- MicroRNA in disease regulation
- Phytochemistry Medicinal Plant Applications
- Medical Malpractice and Liability Issues
- Quality and Safety in Healthcare
- Health and Lifestyle Studies
- Patient Safety and Medication Errors
- Phytochemistry and Bioactive Compounds
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Psidium guajava Extracts and Applications
- Advances in Oncology and Radiotherapy
- Public Health and Environmental Issues
- Healthcare Systems and Reforms
- Public Health Policies and Education
- Childhood Cancer Survivors' Quality of Life
- BRCA gene mutations in cancer
University of Nariño
2010-2023
Survival is a key metric of the effectiveness health system in managing cancer. We set out to provide comprehensive examination worldwide variation and trends survival from brain tumors adults, by histology.We analyzed individual data for adults (15-99 years) diagnosed with tumor (ICD-O-3 topography code C71) during 2000-2014, regardless behavior. Data underwent 3-phase quality control as part CONCORD-3. estimated net 11 histology groups, using unbiased nonparametric Pohar Perme...
Abstract Background Global variations in survival for brain tumors are very wide when all histological types considered together. Appraisal of international differences should be informed by the distribution histology, but little is known beyond Europe and North America. Methods The source analysis was CONCORD database, a program global surveillance cancer trends, which includes tumor records individual patients from more than 300 population-based registries. We aged 0-99 years who were...
Abstract Introduction Tumors of the central nervous system are among leading causes cancer-related death in children. Population-based cancer survival reflects overall effectiveness a health care managing cancer. Inequity access to world-wide may result disparities. Methods We considered children (0–14 years) diagnosed with brain tumor during 2000–2014, regardless behavior. Data underwent rigorous, three-phase quality control as part CONCORD-3. implemented revised version International...
In Colombia it is necessary to continue producing quality and continuously updated information on the magnitude of cancer, derived from population-based cancer registries contribute decision making, implementation strategies for health promotion, prevention treatment in order reduce impact population.To describe incidence, mortality trends Pasto-Colombia 1998 2012.Observational descriptive study morbi - due malignant tumours Pasto. The collection, processing systematization data, was carried...
Introducción: Las percepciones de los usuarios frente a servicios salud son indicadores indispensables calidad sobre procesos atención sanitaria. Objetivo: Conocer las una red pública del municipio Pasto, Colombia la primer nivel atención. Materiales y métodos: Investigación cualitativa con enfoque histórico hermenéutico 28 participantes, centros rurales urbanos. técnicas recolección información desarrolladas fueron entrevistas semiestructuradas un grupo focal. El proceso investigativo...
Estimation of survival requires follow-up patients from diagnosis until death ensuring complete and good quality data. Many population-based cancer registries in low- middle-income countries have difficulties linking registry data with regional or national vital statistics, increasing the chances cases lost to follow-up. The impact on estimates small (<500 cases) has been understudied, bias could be larger than registries. We simulated scenarios based idealized real three assess loss...
En este artículo se presenta uno de los resultados del proyecto investigación denominado: Detección patrones supervivencia en mujeres con cáncer invasivo cuello uterino técnicas minería datos , utilizando como fuente principal la información almacenada base Registro Poblacional Cáncer Municipio Pasto (Colombia). Aplicando metodología para proyectos CRISP-DM, construyó, limpió y transformó un repositorio las que fueron diagnosticadas entre años 1998 2002, una ventana observación hasta el...
El extracto acuoso y el aceite esencial de la pulpa frutos maduros Carica candamarcensis Hook. f. (1875) (chilacuán, papayuela clima frío) presentan actividad in vitro anti-Helicobacter pylori, por lo cual se consideran promisorios para realizar una terapia complementaria controlar infección gástrica esta bacteria. presente trabajo contribuye a profundizar en estudio estos extractos evaluando: a) citotoxicidad mediante análisis viabilidad linfocitos humanos aislados método tradicional...
Helicobacter pylori infection affects approximately half of world’s population, is acquired in infancy and has been associated with the development chronic gastritis, peptic ulcers stomach cancer adulthood. The usual treatment that includes two or three antibiotics led to problems bacterial resistance, decreased effectiveness, price safety; showing need develop alternative therapies. Public Health Research Group University Narino (Pasto, Colombia) found essential oils Rosmarinus officinalis...
Background: MicroRNAs are related to human cancers, including cervical cancer (CC) caused by HPV. In 2018, approximately 56.075 cases and 28.252 deaths from this were registered in Latin America the Caribbean according GLOBOCAN reports. The main molecular mechanism of HPV CC is integration viral DNA into hosts' genome. However, different variants genome can result mechanisms, specifically involving microRNAs (miRNAs). Methods: miRNAs associated with obtained literature, miRNA sequences four...
Introducción: La información producida permanentemente por los registros poblacionales de cáncer es el insumo utilizado tomadores decisiones del sistema salud local y nacional para planificar las estrategias prevención evaluar impacto sus intervenciones. Objetivo: Determinar la incidencia mortalidad en municipio Pasto Colombia periodo 2013-2017. Métodos: Estudio observacional descriptivo morbimortalidad cáncer. recolección procesamiento se realizaron siguiendo recomendaciones IARC. Las tasas...
Introducción: El consumo de sustancias psicoactivas (SPA) en el entorno universitario ha sido una problemática salud pública que es necesario abordar para fortalecer desarrollo integral los estudiantes. Objetivo: Indagar sobre elementos teóricos y metodológicos permitan prevenir, controlar mitigar la al interior Universidad. Materiales métodos: proceso investigación se desarrolló bajo lógica del paradigma cualitativo, con un diseño tipo etnográfico; construcción estrategia metodológica...
We evaluated the effect of total macerate (TM) and seed oil (SO) mature Carica candamarcensisfruits, on release Matrix metalloproteinase 9 (MMP9) phosphorylation MAPK in neutrophils. The antioxidant capacity these extracts was by ABTS assay. Neutrophils stimulated with different dilutions TM or SO were analyzed for cytotoxicity, MMP9 release, phosphorylation, using trypan blue exclusion assays, zymography, immunoblotting, respectively. Both show activity, being higher TM; none presented...