A5100324155- Wastewater Treatment and Nitrogen Removal
- Pharmaceutical and Antibiotic Environmental Impacts
- Phosphorus and nutrient management
- Analytical chemistry methods development
- Microbial Community Ecology and Physiology
- Catalytic C–H Functionalization Methods
- Antibiotic Resistance in Bacteria
- Constructed Wetlands for Wastewater Treatment
- Enzyme Production and Characterization
- Adsorption and biosorption for pollutant removal
- Ophthalmology and Visual Impairment Studies
- Microbial Fuel Cells and Bioremediation
- Sulfur-Based Synthesis Techniques
- Water Treatment and Disinfection
- Amyotrophic Lateral Sclerosis Research
- Corneal surgery and disorders
- Alzheimer's disease research and treatments
- Advanced battery technologies research
- Video Analysis and Summarization
- Environmental Toxicology and Ecotoxicology
- Microbial Metabolites in Food Biotechnology
- Glaucoma and retinal disorders
- Catalytic Alkyne Reactions
- Electrocatalysts for Energy Conversion
- Peroxisome Proliferator-Activated Receptors
Tsinghua University
2018-2025
Institute of High Energy Physics
2022-2025
Hunan Agricultural University
2025
Northeast Forestry University
2025
Dongguan University of Technology
2023-2025
University of Chinese Academy of Sciences
2020-2025
Harbin Institute of Technology
2018-2025
Beihang University
2025
Tsinghua–Berkeley Shenzhen Institute
2020-2024
Shijiazhuang Tiedao University
2022-2024
Extensive antibiotic use increases the environmental presence of their residues and may accelerate development resistance, although this remains poorly understood at environmentally relevant concentrations. Herein, susceptible Escherichia coli K12 was continuously exposed to five antibiotics such concentrations for 100 days. The de novo-evolved mutants rapidly obtained fluoroquinolone resistance within 10 days, as indicated by 4- 16-fold augmentation minimum inhibitory against enrofloxacin...
The p62/sequestosome 1 protein has been identified as a component of pathological inclusions in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). P62 also implicated autophagy, process mass degradation intracellular proteins and organelles. Autophagy is critical pathway for degrading misfolded and/or damaged proteins, the copper-zinc superoxide dismutase (SOD1) mutants linked to familial ALS. We previously reported that p62 interacted with ALS SOD1...
The copper-catalyzed cyclization of activated alkenes with cyclobutanone O-acyl oximes under redox-neutral conditions has been reported. This facile protocol provided an efficient approach to a variety cyanoalkylated oxindoles and dihydroquinolin-2(1H)-ones broad substrate scope excellent functional group tolerance. In this reaction, sequential C–C bond cleavage, radical addition, processes were involved, wherein multiple bonds constructed in one-pot reaction. Mechanistic studies suggest...
Biodegradation is an important route for the removal of sulfamethazine (SMZ), one most commonly used sulfonamide antibiotics, in environment. However, little information known about kinetics, products, and pathways SMZ biodegradation owing to complexity its enzyme-based biotransformation processes. In this study, SMZ-degrading strain A01 belonging genus Paenarthrobacter was isolated from SMZ-enriched activated sludge reactors. The bacterial cells were rod-shaped with transient branches...
Abstract Wastewater biotreatment systems harbor a rich diversity of microorganisms, and the effectiveness largely depends on activity these microorganisms. Specifically, viruses play crucial role in altering microbial behavior metabolic processes throughout their infection phases, an aspect that has recently attracted considerable interest. Two metagenomic approaches, viral‐like particle‐concentrated (VPC, representing free particles) non‐concentrated (NC, cellular fraction), were employed...
Conventional biological nutrient removal processes rely on external aeration and produce significant carbon dioxide (CO2) emissions. This study constructed a phototrophic simultaneous nitrification-denitrification phosphorus (P-SNDPR) system to treat low nitrogen (C/N) ratios wastewater investigated the impact of sludge retention time (SRT) performance, conversion pathway, microbial structure. Results showed that P-SNDPR at SRT 15 days had highest capacity, achieving over 85% 98% phosphorus,...
A visible-light-mediated decarboxylative cyclization of N-acyloxylphthalimides with vinyl azides has been developed under metal-free conditions. This protocol features mild conditions, a broad substrate scope, and an excellent functional group tolerance, thus providing facile efficient access to substituted phenanthridines. Control experiments revealed that the reaction proceeded via radical process.
Rheumatoid arthritis (RA) refers to an autoimmune rheumatic disease that imposes a huge burden on patients and society. Early RA diagnosis is critical preventing progression selecting optimal therapeutic strategies more effectively. In the present study, aim was at examining RA's diagnostic signatures effect of immune cell infiltration in this pathology.Gene Expression Omnibus (GEO) database provided three datasets gene expressions. Firstly, study adopted R software for identifying...
Background: Post-stroke depression (PSD) is most prevalent during the rehabilitative period following a stroke. Recent studies verified effects of repetitive transcranial magnetic stimulation therapy (rTMS) and mindfulness-based stress reduction (MBSR) in patients with depression. However, effectiveness prospect application PSD remain unclear. This study sought to evaluate combined intervention based on rTMS MBSR for physical mental state patients. Methods: A randomized, double-blind,...
Abstract Intramolecular amination of remote aliphatic C–H bonds via hydrogen-atom transfer reactions has become a powerful tool for accessing saturated nitrogen-containing heterocycles. However, the formation six-membered rings or oxa-heterocycles remains formidable challenge Hofmann–Löffler–Freytag reactions. Here we show how by simply combining bench-stable (bis(trifluoroacetoxy)iodo)benzene and hexafluoroisopropanol (HFIP) can switch from well-established mechanism to different versatile...
Metal-catalyzed cyanoalkylation/cyclization of olefinic 1,3-dicarbonyls with cycloketone oxime esters has been developed under redox-neutral conditions. This protocol provided a straightforward approach to diverse cyanoalkylated 2,3-dihydrofurans via tandem ring-opening/addition/cyclization process.