A5052196961- Land Use and Ecosystem Services
- Microfluidic and Capillary Electrophoresis Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Monoclonal and Polyclonal Antibodies Research
- COVID-19 Clinical Research Studies
- Urban Green Space and Health
- Underground infrastructure and sustainability
- TiO2 Photocatalysis and Solar Cells
- Digital Media and Visual Art
- Medical Research and Treatments
- Educational Environments and Student Outcomes
- Cultural Industries and Urban Development
- Advanced Photocatalysis Techniques
- Remote Sensing and Land Use
- Urban Heat Island Mitigation
- Aluminum Alloys Composites Properties
- Occupational Health and Safety Research
- Intermetallics and Advanced Alloy Properties
- Educational Reforms and Innovations
- Electronic and Structural Properties of Oxides
- Risk and Safety Analysis
- Vibrio bacteria research studies
- Wildlife-Road Interactions and Conservation
Hebei University of Technology
2022-2023
Harbin Institute of Technology
2012-2020
Shenzhen Institute of Information Technology
2020
Ministry of Industry and Information Technology
2019
Zhejiang University
2019
Microfluidics system enables high-throughput functional screening of antibodies for cancer immunotherapy.
Urban agglomerations have become a new geographical unit in China, breaking the administrative fortresses between cities, which means that population and economic activities cities will more intensive future. Constructing optimizing ecological security pattern of urban is important for promoting harmonious social-economic development protection. Using Harbin-Changchun agglomeration as case study, we identified sources based on evaluation ecosystem functions. Based resistance surface modified...
Forming a large-scale droplet array plays an important role for microfluidic droplet-based high-throughput screening and analysis. Herein, we describe simple rapid method to form two-dimension (2D) by using microcage chip. Differing from the previous formation methods, microcages formed being surrounded multiple micropillars could rapidly spread oil phase through gaps between trap droplets with fast speed convenient operation. We 2D monolayer containing approximately 1 000 on 5.5 cm × chip...
The settlement space along China’s Grand Canal is an important part of cultural heritage, boasting high value conservation and inheritance as a museum local culture in active state. paper aimed at revealing the current situation satisfaction with environment Tianjin Section from perspective resident perception. We set up structural equation model to perform empirical analysis inherent relation components law influencing its research results show that ecological factor life exerted positive...
With the development of rapid urbanization, urban expansion and traffic jams are serious problem city development. Underground railway plays an important role in public transport, which helps to ease congestion. Because frequent accidents underground railway, research safety planning strategies lays foundation for research. This paper reveals situation Harbin Metro Line 1 China from passenger consciousness, equipment environment, management factors, through a series subjective questionnaire...
Urban park green areas are part of territorial space planning, shouldering the mission providing residents with high-quality ecological products and public space. Using a combination several measurement models such as BCG (Boston Consulting Group) matrix, ESDA (Exploratory Spatial Data Analysis), MLR (Machine Learning Regression), GWR (Geographically Weighted GeoDetector, this paper presents an empirical study on changes in Park Green Areas (UPGAs) Grand Canal China. By quantitatively...
In order to recognize the urban development status and select spatial path, this paper, with analysis method of GIS data Remote Sense, simulates Harbin construction land expansion two scenarios, suitability ecological importance. According landscape ecology method, patterns scenarios are compared analyzed using patch number (NP), area ratio (PLAND), shape index (LSI) aggregation (AI). The results show that degree fragmentation dispersion in increases intensity. And importance is lower than scenarios.
Abstract Currently high throughput approaches are lagged for isolation of antibodies whose function goes beyond simple binding, which have prevented the next generation cancer immunotherapeutics, such as bispecific T cell engager or agonist antibody costimulatory receptor, from reaching their full potential. Here we developed a highly efficient droplet-based microfluidics platform combining with lentivirus transduction system that enables functional screening millions antibodies. To showcase...
Abstract The pandemic Coronavirus Disease 2019 (COVID-19) causes noticeable morbidity and mortality worldwide. In addition to vaccine antiviral drug therapy, the use of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) neutralizing antibodies for treatment purposes is a viable alternative. this study, we aimed profile humoral responses identify against SARS-CoV-2 using high-throughput single-cell sequencing that tailored B cell receptor sequencing. From two convalescent patients...
With the improvement of material living standards, degree concern for urban leisure space is more increasingly. Public open carrier demand people to experience. And experience that enriches activities and enhances vitality feelings public people. The paper analyzes current situation central Hulan based on perspective. According entertainment, esthetic, escapist education needs, put forward principles. tactics system planning place. Finally it has guiding significance place center Hulan.
副溶血弧菌(Vibrio parahaemolyticus，VP)在海洋环境中普遍存在，是能够引起人类中毒的重要食源性病原菌之一，研究其生长受环境因子的影响规律对科研和社会生活都具有重要意义。本研究采用响应面法研究温度、盐度、pH、磷酸盐、硝氮和氨氮对VP的生长影响，以探讨、评估这6种理化因子的综合作用结果。首先用Design-Expert软件中的Box Behnken中心组合原则设计三因素三水平响应面实验，再进行响应面分析，以培养基光密度(OD600 nm)值为生长状态参数，获得该菌的最佳培养参数：温度为34.5℃，盐度为3%，酸碱度pH为8.0。在此基础上，考察NaNO3、NH4Cl和Na3PO4对VP生长的影响并建立模型。回归方程决定系数R2=0.9217，校正系数R2=0.8211，回归模型F=9.16, P=0.004，表明该模型具有较好的准确性。实验所得实测值与模型演算理论值拟合良好，皆表明磷酸盐、硝氮和氨氮对VP的生长都具有抑制作用。
Abstract The pandemic Coronavirus Disease 2019 (COVID-19) causes noticeable morbidity and mortality worldwide. In addition to vaccine antiviral drug therapy, the use of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) neutralizing antibodies for treatment purposes is a viable alternative. this study, we aimed profile humoral responses identify against SARS-CoV-2 using high-throughput single-cell sequencing that tailored B cell receptor sequencing. From two convalescent patients...