A5026850872- Maternal Mental Health During Pregnancy and Postpartum
- Infant Development and Preterm Care
- Birth, Development, and Health
- Child and Adolescent Psychosocial and Emotional Development
- Neonatal Respiratory Health Research
- Neuroendocrine regulation and behavior
- Assisted Reproductive Technology and Twin Pregnancy
- Global Maternal and Child Health
- Intellectual Capital and Performance Analysis
- Stress Responses and Cortisol
- Attachment and Relationship Dynamics
- Firm Innovation and Growth
- Healthcare Systems and Reforms
- Management, Economics, and Public Policy
- Emergency and Acute Care Studies
- Child Nutrition and Water Access
- Social and Educational Sciences
- Psychosomatic Disorders and Their Treatments
- ERP Systems Implementation and Impact
- Mosquito-borne diseases and control
- Early Childhood Education and Development
- Dementia and Cognitive Impairment Research
- Accounting and Organizational Management
- Viral Infections and Vectors
- Family Support in Illness
University of North Carolina at Chapel Hill
2024
North Carolina Division of Public Health
2022
Imperial College London
2006-2012
Hammersmith Hospital
2008-2010
Wexham Park Hospital
2007
University of Rochester
2007
Maudsley Hospital
1990
Abstract Experimental animal findings suggest that early stress and glucocorticoid exposure may program the function of hypothalamic–pituitary–adrenal (HPA) axis in offspring. The extension these to human development is not yet clear. A prospective longitudinal study was conducted on 125 mothers their normally developing children. Amniotic fluid obtained at, average, 17.2 weeks gestation; infant behavior cortisol response a separation–reunion assessed at 17 months. predicted stress: infants...
Background: Animal studies have shown that prenatal stress has persisting effects on several aspects of offspring development; more recent show this effect may be eliminated by positive postnatal rearing. Human anxiety/stress are now also beginning to document links between antenatal stress/anxiety and behavioural cognitive development the child; however, there is no human evidence as whether early caregiving environment moderates child outcomes. Methods: Antenatal measures were collected...
Summary Introduction Foetal exposure to testosterone is increasingly implicated in the programming of future reproductive and nonreproductive behaviour. Some outcomes associated with prenatal may be predicted from stress, suggesting a link between them. The peak serum levels foetus are thought around 14–18 weeks’ gestation, we explored at different gestations. Although best investigated foetal plasma, this now difficult because decline frequency blood sampling; study, used amniotic fluid as...
Abstract Objectives To assess whether anticipation of amniocentesis is linked with maternal anxiety, and this anxiety associated increased plasma cortisol. Methods Two hundred fifty‐four women awaiting a morning for karyotyping (gestation range 15–37 weeks, median 17 weeks) completed Spielberger state trait inventory (STAI) questionnaires, provided blood samples immediately before the procedure cortisol assay. Six five at mean gestation 20 attending same hospital routine ultrasound but not...
Summary Objective There is increasing evidence that antenatal stress has long‐lasting effects on child development, but there less accord the mechanisms and gestational window of susceptibility. One possible mechanism by foetal exposure to maternal cortisol. To explore this, we investigated relationship between cortisol in plasma amniotic fluid, any moderating influence age. Patients measurements Two hundred sixty‐seven women awaiting amniocentesis for karyotyping were studied. Samples...
Zika virus infection during pregnancy can cause congenital brain and eye abnormalities is associated with neurodevelopmental (1-3). In areas of the United States that experienced local transmission, prevalence birth defects potentially related to increased in second half 2016 compared first (4). To update previous report, CDC analyzed population-based surveillance data from 22 states territories estimate infection, regardless laboratory evidence or exposure virus, among pregnancies completed...
Abstract Background In 2016, Zika virus (ZIKV) was recognized as a human teratogen. North Carolina (NC) had no local transmission of ZIKV but infants with relevant birth defects, including severe brain anomalies, microcephaly, and eye abnormalities, require specialized care services, the costs which have not yet been quantified. The objective this study is to examine NC Medicaid healthcare expenditures for defects potentially related compared reported defects. Methods Data sources...
In the USA each year, there are approximately 3400 sudden unexpected infant (<1 year of age) deaths (SUID) which occur without an obvious cause before investigation. SUID includes causes death (COD) undetermined/unknown, sleep-related suffocation/asphyxia and syndrome (SIDS); these often called subtypes. Three common ways subtypes grouped (SUID subtype groups) include International Classification Diseases (ICD) Codes, Case Registry Categories or Child Death Review (CDR)-Assigned Causes....