- Maternal Mental Health During Pregnancy and Postpartum
- Infant Development and Preterm Care
- Child and Adolescent Psychosocial and Emotional Development
- Birth, Development, and Health
- Neurotransmitter Receptor Influence on Behavior
- Stress Responses and Cortisol
- Parkinson's Disease Mechanisms and Treatments
- Migraine and Headache Studies
- Receptor Mechanisms and Signaling
- Neuroendocrine regulation and behavior
- Pediatric Pain Management Techniques
- Tryptophan and brain disorders
- Neuroscience and Neuropharmacology Research
- Alcoholism and Thiamine Deficiency
- Neonatal Respiratory Health Research
- Alcohol Consumption and Health Effects
- Infant Health and Development
- Child Nutrition and Feeding Issues
- Biochemical effects in animals
- Maternal and Perinatal Health Interventions
- Child Abuse and Trauma
- Heart Failure Treatment and Management
- Polyamine Metabolism and Applications
- Neonatal and fetal brain pathology
- Nitric Oxide and Endothelin Effects
Imperial College London
2015-2025
Hammersmith Hospital
1998-2025
John Wiley & Sons (United States)
2019
Michigan State University
2019
Hudson Institute
2019
Centre for Mental Health
2017
Queen Charlotte's and Chelsea Hospital
1994-2015
Cardiff University
2015
University of London
1983-2012
Imperial Valley College
2005-2007
Background Animal experiments suggest that maternal stress and anxiety during pregnancy have long-term effects on the behaviour of off spring. Aims To test hypothesis antenatal predicts behavioural problems at age 4 years. Method Data were collected multiple postnatal assessments depression, obstetric risks, psychosocial risks children's behavioural/emotional (n=7448). Results Antenatal predicted in boys (OR=2.14,95% CI 1.48−3.10) girls (OR=1.88,95% 1.3–2.69) after accounting for covariates....
Background: Previous animal investigations link antenatal stress with a range of persistent behavioural abnormalities in the offspring. The current study examined if effect was also found humans through middle childhood. Methods: is based on Avon Longitudinal Study Parents and Children (ALSPAC), prospective, community‐based that has followed cohort women from pregnancy. Self‐report measures maternal anxiety depression were assessed at repeated intervals pregnancy postnatal period. Children's...
<h3>Abstract</h3> <b>Objective:</b> To investigate whether maternal anxiety in the third trimester is associated with an increased uterine artery resistance index. <b>Design:</b> Cohort based study. <b>Subjects:</b> 100 pregnant women, a mean gestation of 32 weeks. <b>Outcome measures:</b> Self rating Spielberger questionnaire for state and trait anxiety, blood flow waveform patterns as assessed by colour Doppler ultrasound. <b>Results:</b> A significant association was found between index...
Abstract Developmental or fetal programming has emerged as a major model for understanding the early and persisting effects of prenatal exposures on health development child adult. We leverage power 14-year prospective study to examine anxiety, key candidate in developmental model, symptoms behavioral emotional problems across five occasions measurement from age 4 13 years. The is based Avon Longitudinal Study Parents Children cohort, prospective, longitudinal large community sample west...
Background Prenatal loss, the death of a fetus/child through miscarriage or stillbirth, is associated with significant depression and anxiety, particularly in subsequent pregnancy. Aims This study examined degree to which symptoms anxiety previous loss persisted following successful Method Data were derived from Avon Longitudinal Study Parents Children cohort, longitudinal cohort west England that has followed mothers pregnancy into postnatal period. A total 13 133 reported on number...
Decisions about the use of psychotropic medication in pregnancy are an ongoing challenge for clinicians and women with mental health problems, owing to uncertainties around risks illness itself mother fetus/infant, effectiveness medications fetus/infant from utero exposure or via breast milk. These consensus guidelines aim provide pragmatic advice regarding these issues. They divided into sections on untreated pregnancy; general principles using drugs perinatal period; benefits harms...