Palika Wetchakul

ORCID: 0000-0002-3824-9712
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Essential Oils and Antimicrobial Activity
  • Nigella sativa pharmacological applications
  • Acupuncture Treatment Research Studies
  • Wound Healing and Treatments
  • Pharmacological Effects of Natural Compounds
  • Phytochemistry and Biological Activities
  • Tea Polyphenols and Effects
  • GABA and Rice Research
  • Phytochemistry and biological activity of medicinal plants
  • Gastrointestinal motility and disorders
  • Bee Products Chemical Analysis
  • Diabetic Foot Ulcer Assessment and Management
  • Antioxidant Activity and Oxidative Stress
  • Natural Antidiabetic Agents Studies
  • Ginger and Zingiberaceae research
  • Genomics, phytochemicals, and oxidative stress
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Botanical Research and Applications
  • Hibiscus Plant Research Studies
  • Phytoestrogen effects and research
  • Medicinal Plants and Neuroprotection
  • Pharmacology and Obesity Treatment
  • Digestive system and related health
  • Genetics, Aging, and Longevity in Model Organisms

Walailak University
2021-2025

Prince of Songkla University
2019

This study assessed the antioxidant activities and bioactive maker of Tri-Than-Thip tea (Tri-TTa) to provide database support for use Tri-Than Thip remedy according Thai Pharmaceutical Textbook aims develop herbal medicine or food from natural products. Tri-TTa components were tested scavenging activity (DPPH assay, ABTS assay), chain-breaking/iron ion chelating (Metal Chelating Activity; MAC, ferric-reducing power activity; FRAP), superoxide anion radical (NBT oxygen capacity (ORAC total...

10.1016/j.jafr.2024.101131 article EN cc-by-nc-nd Journal of Agriculture and Food Research 2024-03-26

Background. The world population has exhibited increased trust in folk medicine, including Thai for the treatment of various illnesses. However, comparative antioxidant and cytoprotective activities against oxidative damage Tri-Than-Thip (Tri-TT), a remedy, have not been reported. Objectives. purpose this study was to evaluate capacities Tri-TT its herbal constituents, Cassia fistula, Pithecellobium dulce, Ficus benjamina. Methods. Extracts were obtained from constituents. free radical...

10.1155/2022/4477003 article EN Evidence-based Complementary and Alternative Medicine 2022-01-31

The imbalance between the generation of free radicals and natural cellular antioxidant defenses, known as oxidative stress, can cause oxidation biomolecules further contribute to aging-associated diseases. purpose this study was evaluate capacities Thai traditional tonifying preparation, Jatu-Phala-Tiga (JPT) its herbal ingredients consisting Phyllanthus emblica, Terminalia arjuna, chebula, bellirica assess effect on longevity.Antioxidant activities various extracts obtained from JPT...

10.1186/s12906-019-2626-1 article EN cc-by BMC Complementary and Alternative Medicine 2019-08-13

A traditional preparation of Ya-Samarn-Phlae (T-YaSP) consists Garcinia mangostana L., Oryza sativa Curcuma longa and Areca catechu L. has been used in Thai medicine as an infused oil for treating chronic diabetic wounds. It is reputed its antibacterial, antioxidant, wound-healing properties. Despite use, scientific validation the mechanisms underlying wound healing remains limited. This study aims to develop a novel gauze dressing impregnated with ointment containing T-YaSP (YaSP) enhance...

10.3389/fphar.2025.1574715 article EN cc-by Frontiers in Pharmacology 2025-04-09

Phy-Blica-D is a traditional Thai polyherbal formula that has reduced oxidative stress in non-communicable diseases. However, evidence supporting the gastroprotective effects of not been previously reported. Therefore, this study aimed to evaluate against gastric ulcers rats and investigate potential underlying mechanism. To estimate possible mechanisms action, we examined levels markers, such as reactive oxygen species (ROS) malondialdehyde (MDA), well antioxidant enzymes, including...

10.3390/nu14010172 article EN Nutrients 2021-12-30

Nigella sativa L. and black seeds are traditionally used for cooking medicinal purposes in Arab other countries. Although N. seed extract has many known biological effects, the effects of cold-pressed oil poorly understood. Therefore, objective this study was to investigate gastroprotective subacute oral toxicity (BSO) an animal model. The BSO (50% 100%; 1 mg/kg) were tested using acute experimental models ethanol-induced gastric ulcers. Gross histological lesions, ulcerated areas, ulcer...

10.3390/nu15061532 article EN Nutrients 2023-03-22

Tri-Tharn-Thip, a traditional Thai medicine, is herbal formula used to promote milk production, wound healing, and gastric ulcer. However, no previous studies have reported its anti-gastric ulcer activity. This study aimed evaluate the gastroprotective effects of Tri-Tharn-Thip tea (Tri-TTa) explore potential mechanisms action by measuring levels reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), mucin, inducible nitric oxide...

10.1016/j.sajb.2024.05.027 article EN cc-by-nc-nd South African Journal of Botany 2024-05-18

The plant Nigella sativa (NS) has a rich history in folk medicine, being utilized for various illnesses and as tonic drugs. Furthermore, thymoquinone (TQ), major compound found the seeds of NS, may exhibit antioxidant activity. In addition to black candles, traditional medicine employs olive oil honey nourish body. Some systems combine honey, improved efficacy; however, knowledge regarding properties seed (BSO), BSO with (BSOO), (BSOH) remains limited. Therefore, this study, we investigated...

10.1016/j.jafr.2023.100891 article EN cc-by-nc-nd Journal of Agriculture and Food Research 2023-11-25

Tri-Yannarose is a Thai traditional herbal medicine formula composed of Areca catechu, Azadirachta indica, and Tinospora crispa. It possesses antipyretic, diuretic, expectorant, appetite-stimulating effects. This study aimed to evaluate the antioxidant activities, cytotoxicity, chemical constituents an aqueous extract following recipe its plant ingredients. The phytochemical analysis was performed using LC-QTOF-MS. Antioxidant activities were determined DPPH, ABTS, TPC, TFC, FRAP, NBT, MCA,...

10.3390/antiox12071428 article EN cc-by Antioxidants 2023-07-15

Herbal galactagogues have been widely used as a treatment for postpartum hypogalactia due to the potential side effects associated with pharmacological therapy. Tri-Than-Thip (Tri-TT) is Thai herbal medicine remedy that contains three main components: Cassia fistula, Pithecellobium dulce, and Ficus benjamina. These components are believed properties contribute milk production. However, despite traditional use of Tri-TT, there lack academic evidence supporting its efficacy in enhancing...

10.7150/ijms.83869 article EN cc-by-nc International Journal of Medical Sciences 2023-01-01

Lower urinary tract symptoms (LUTS) are not only more common in the elderly, but various pathophysiological pathways suggest a link between hyperglycemia and LUTS. Due to long-standing traditional use of medicinal plants Thailand, present work aims establish safety efficacy Aphayathikun (AP), recorded Thai Traditional drug for The standardized decoction AP has been established, phenolic flavonoid content, antioxidant activity, vivo toxicity were assessed using previously published methods. A...

10.26538/tjnpr/v7i11.12 article EN cc-by-nc-nd Tropical Journal of Natural Product Research 2023-12-01
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