A5084624703- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Cancer Cells and Metastasis
- Estrogen and related hormone effects
- Reproductive Physiology in Livestock
- Gynecological conditions and treatments
- Preterm Birth and Chorioamnionitis
- Single-cell and spatial transcriptomics
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Pregnancy-related medical research
Gansu Provincial Hospital
2022-2025
Abstract Background The polymorphisms of the FOXP3 gene may mediate abnormalities in Tregs, leading to an imbalance maternal‐fetal immune tolerance and ultimately resulting recurrent spontaneous abortion (RSA). This meta‐analysis aims assess potential association between susceptibility RSA using five specific single nucleotide (SNPs). Materials methods By conducting a comprehensive search across databases such as EMBASE, PubMed, Web Science, Cochrane Library, CNKI, Wanfang, CBM, we...
<title>Abstract</title> The full text of this preprint has been withdrawn by the authors due to author disagreement with posting preprint. Therefore, do not wish work be cited as a reference. Questions should directed corresponding author.
Abstract Recurrent spontaneous abortion (RSA) is a common complication in pregnant women. Autophagy impacts the initiation and progression of various diseases,the specific role autophagy process endometrial decidualization RSA paitents still largely unknown. The purpose this research was to examine involvement autophagy-related genes (ARGs) associated with using bioinformatics approaches.To identify differentially expressed (DEGs), Gene Expression Omnibus database provided gene expression...
<title>Abstract</title> α-enolase (ENO1), as a plasminogen receptor and key enzyme of glycolysis, is highly expressed in cervical cancer, Inhibition ENO1 activity can further inhibit the migration invasion tumor cells by inhibiting glycolsis, growth.In this study, adeno-associated virus (rAAV-ENO1mAb-5) with variable region gene recombinant monoclonal antibody was prepared to mediate targeted entry into cytoplasm observe its growth inhibition effect on cancer cells. The results showed that...
<title>Abstract</title> Background Intrauterine adhesion (IUA) is a common cause of clinically refractory infertility, and there exists significant heterogeneity in the treatment outcomes among IUA patients with similar severity after transcervical resection adhesion(TCRA). The underlying mechanism different occur remains elusive, precise contribution various cell subtypes this process uncertain. Results Here, we performed single-cell transcriptome sequencing on 10 human endometrial samples...
Intrauterine adhesion (IUA) is a common cause of clinically refractory infertility, and there exists significant heterogeneity in the treatment outcomes among IUA patients with similar severity after transcervical resection adhesion(TCRA). The underlying mechanism different occur remains elusive, precise contribution various cell subtypes this process uncertain. Here, we performed single-cell transcriptome sequencing on 10 human endometrial samples to establish atlas differences between who...