A5080073224- Infection Control in Healthcare
- Infection Control and Ventilation
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Medical Device Sterilization and Disinfection
- Dental Research and COVID-19
- Clostridium difficile and Clostridium perfringens research
- SARS-CoV-2 detection and testing
- Mycobacterium research and diagnosis
- SARS-CoV-2 and COVID-19 Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Use and Resistance
- Bacterial biofilms and quorum sensing
- Listeria monocytogenes in Food Safety
- Legionella and Acanthamoeba research
- Antifungal resistance and susceptibility
- COVID-19 and healthcare impacts
- Nosocomial Infections in ICU
- Gut microbiota and health
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- Quality and Safety in Healthcare
- Microscopic Colitis
- Viral gastroenteritis research and epidemiology
Central Texas Veterans Health Care System
2016-2025
Texas A&M University
2014-2024
Bryan College
2015-2024
Olin E. Teague Veterans Medical Center
2024
Texas A&M Health Science Center
2014-2022
Communities In Schools of Orange County
2022
New York Proton Center
2022
Ann Arbor Center for Independent Living
2022
University of Richmond
2022
Oregon Medical Research Center
2022
This paper presents an accelerated ferrate(VI) (FeVIO42-, FeVI) oxidation of contaminants in 30 s by adding one-electron and two-electron transfer reductants (R(1) R(2)). An addition R(2) (e.g., NH2OH, AsIII, SeIV, PIII, NO2-, S2O32-) results FeIV initially, while FeV is generated with the R(1) SO32-). additives, except S2O32-, show enhanced 20-40% target contaminant, trimethoprim (TMP). Comparatively, TMP was up to 100% FeVI. Interestingly, S2O32- (i.e., R(2)) also achieves 100%. Removal...
Abstract Objectives: Prolonged survival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on environmental surfaces and personal protective equipment may lead to these transmitting this pathogen others. We sought determine the effectiveness a pulsed-xenon ultraviolet (PX-UV) disinfection system in reducing load SARS-CoV-2 hard N95 respirators. Methods: Chamber slides respirator material were directly inoculated with exposed different durations PX-UV. Results: For surfaces, for...
There have been several recent reports of Clostridioides difficile infection (CDI) due to isolates with reduced fidaxomicin susceptibility (minimum inhibitory concentration [MIC] ≥ 2 µg/mL). However, the clinical implications are uncertain because achieves high concentrations in intestinal tract. In an acute care hospital, we conducted a 3-year cohort study patients CDI determine frequency and impact on response treatment. Stool specimens were cultured for C. difficile, testing was performed...
Healthcare-acquired infections with methicillin-resistant Staphylococcus aureus (MRSA) are a significant cause of increased mortality, morbidity and additional health care costs in United States. Surface decontamination technologies that utilize pulsed xenon ultraviolet light (PPX-UV) may be effective at reducing microbial burden. The purpose this study was to compare standard manual room-cleaning PPX-UV disinfection technology for MRSA bacterial heterotrophic plate counts (HPC) on...
While research has demonstrated the importance of a clean health care environment, there is lack on role portable medical equipment (PME) play in transmission cycle healthcare-acquired infections (HAIs). This study investigated patterns and sequence contact events among workers, patients, surfaces, hospital environment. Research staff observed patient over six different 24 h periods units. Each encounter was recorded as analyzed using analysis visually represented by network plots. In...
Persistent severe acute respiratory syndrome coronavirus 2 infection is difficult to treat. Here, we report a case of 5-month persistent disease 2019 in an immunocompromised patient who was successfully treated with 30 consecutive days remdesivir. Prolonged remdesivir infusion concurrent cycle threshold monitoring might provide potential solution cure these patients difficult-to-treat infections.
Pathogen transmission from contaminated surfaces can cause hospital-associated infections. Although pulsed xenon ultraviolet (PX-UV) light devices have been shown to decrease hospital room bioburden in the United States, their effectiveness Kingdom (UK) hospitals is less understood.Forty isolation rooms at Queens Hospital (700 beds) North London, UK, were sampled for aerobic bacteria after patient discharge, manual cleaning with a hypochlorous acid-troclosene sodium solution, and PX-UV...
The doffing of personal protective equipment (PPE) after contamination with pathogens such as Ebola poses a risk to health care workers. Pulsed xenon ultraviolet (PX-UV) disinfection has been used disinfect surfaces in hospital settings. This study examined the impact PX-UV on an surrogate virus glass carriers and PPE material examine potential benefits using decontaminate while worn, thereby reducing pathogen load prior doffing. Ultraviolet (UV) safety coverage tests were also conducted....
Talaromyces marneffei infection is a systemic mycosis, caused by dimorphic fungus, an opportunistic pathogen formerly known as Penicillium marneffei. This disease endemic to Southeast Asia and common in human immunodeficiency virus (HIV) infected patients with low CD4 counts. Here we present very rarely reported case of apparent non-immunosuppressed patient presenting decades later non-endemic setting (United States). Our was 75-year-old Caucasian Navy veteran, who served Vietnam part the...
Health care personnel and patients are at risk to acquire severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in health settings, including outpatient clinics ancillary areas.
•The FFUV handheld disinfection device reduces bioburden on hospital surfaces.•The can be used equipment where chemical disinfectants cannot used.•This may provide a safer alternative for users. BackgroundThe filtered far-UV-C (FFUV) is small portable that emits far UV-C at 222 nm. The objective of this study was to evaluate the device's ability kill microbial pathogens surfaces and compare it manual using germicidal sodium hypochlorite wipes.MethodsA total 344 observations (4 from 86...
The SARS-CoV-2 virus steadily evolves, and numerous antigenically distinct variants have emerged over the past three years. Tracking evolution of would help us understand process that generates diverse predict future evolutionary trajectory SARS-CoV-2. Here, we report a unique Omicron lineage identified during an outbreak investigation occurred in residence unit healthcare system. new had four non-synonymous two synonymous mutations apart from its parental lineage. Since this was exclusively...
Abstract Background Despite increasing use of fidaxomicin for Clostridioides difficile infection (CDI), isolates with reduced susceptibility (minimum-inhibitory concentration [MIC] >2 ug/mL) have been rare in surveillance studies. However, there has recent reports clinical associated mutations the RpoB and RpoC genes coding RNA polymerase target fidaxomicin. The implications are uncertain because achieves high concentrations intestinal tract. Whole genome sequencing analysis...
Candida auris is an emerging and often multidrug-resistant fungal pathogen with exceptional ability to persist on hospital surfaces. These surfaces can act as a potential source of transmission. Therefore, effective disinfection strategies are urgently needed. We investigated the efficacy ultraviolet C light (UV-C) for C. isolates belonging 4 different clades.In vitro testing was conducted using 106 colony-forming units (CFU) spread 20-mm diameter steel carriers exposed broad-spectrum UV-C...