A5023178430- Cancer, Hypoxia, and Metabolism
- Adrenal and Paraganglionic Tumors
- Thyroid Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Health, Education, and Aging
- Thyroid and Parathyroid Surgery
- Health and Lifestyle Studies
- Health, Nursing, Elderly Care
- Glioma Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Neuroblastoma Research and Treatments
- Cancer, Lipids, and Metabolism
- Cancer-related Molecular Pathways
- Primary Care and Health Outcomes
- Innovations in Medical Education
- Hormonal Regulation and Hypertension
Irmandade da Santa Casa de Misericórdia de São Paulo
2021
Universidade Federal de Alagoas
2013-2017
A partir da criação do Sistema Único de Saúde (SUS) e implantação Programa Família (PSF), exige-se que os novos profissionais saúde pública desenvolvam, desde cursos graduação, visão integral paciente olhar crítico para a realidade comunidade sua própria atuação no PSF. Com esse objetivo, Faculdade Medicina Universidade Federal Alagoas (Famed-Ufal), em 2005, introduziu modificações curriculares permitem aos estudantes uma vivência mais ampla contexto Atenção Primária à (APS). Este relato...
Although thyroid microcarcinoma (TMC) usually has a favorable prognosis, some patients present higher risk of disease recurrence or persistence. Thus, we aimed at identifying possible factors associated with an incomplete response to therapy in TMC.This was retrospective study 517 TMC treated total thyroidectomy, without radioactive iodine (RAI) therapy, reclassified after 1.1 ± 0.4 years according the treatment into "favourable" (excellent/indeterminate) "unfavorable"...
Objetivo: determinar o perfil epidemiológico e clínico de pacientes com acromegalia no Estado Alagoas. Métodos: trata-se um estudo descritivo, observacional, que foi realizado na Farmácia Medicamentos Excepcionais do Alagoas, abrangendo 12 dessa instituição, correspondendo a 85% dos acromegálicos Resultados: estudados, média idade 50,8 +/- 12,1 anos e, momento diagnóstico, uma 44,5 11,6 anos. Foram realizados exames imagem em 91,6% pacientes, se evidenciou macroademona hipofisário...
Abstract Introduction: Pheochromocytomas and Paragangliomas (PGL) are rare tumors originating from chromaffin cells. They may be sporadic or associated with familial inherited genetic syndromes around 50-80%. There several PGL syndromes, the most common being 1 (SDHD mutations), 2 (SDHAF), 3 (SDHC), 4 (SDHB), 5 (SDHA), 6 (SLC25A11) 7 (DLST). SDHB mutations generate a higher probability of malignant PGL, as well risk renal, GIST pituitary neoplasms. We report case patient positive family...
Abstract Introduction: Multiple endocrine neoplasia type 2A (MEN 2A) is a autosomal dominant transmission inherited syndrome which oncogenesis based on germline mutations with RET proto-oncogene function gain. Patients have medullary thyroid carcinoma (CMT) and some develop unilateral or bilateral pheochromocytoma and/or primary hyperparathyroidism, its frequency depends the mutation. We present case of mother daughter marfanoid habitus MEN confirmed by genetic analysis that identified...
Abstract Introduction Neuroendocrine Neoplasms are rare, with an incidence of 5 to 100,000 inhabitants, constituting 1% all malignancies, presenting high survival rates in general, even metastatic diseases. However, those poorly differentiated, as the following case, is around 4% years. We will describe a case primary neuroendocrine tumor brain, which uncommon literature. Clinical A 26 years women was referred ER Santa Casa de São Paulo, January 2019, be evaluated by neurosurgery, due...
Abstract Background: We will describe a Brazilian family whose index case had pheochromocytoma and in the evaluation of genetic panel by Next Generation Sequence (NGS), germline pathogenic variants TMEM127 TP53 genes were identified. Clinical Case: A 32-year-old female patient with clinical picture paroxysms difficult to control arterial hypertension, personal history stroke acute myocardial infarction. She 6.5 cm tumor right adrenal urine metanephrine levels 5.5 mg / g creatinine (VR...
Abstract Background: We report the case of a patient with VHL Syndrome an adrenal lesion compatible non-functioning pheochromocytoma and it’s diagnostic management. Case Report: JMN, female, 32 years old, referred for screening syndrome, after diagnosis in sister, who has clear cell renal carcinoma (ccRCC), cerebellar hemangioblastoma genetic analysis, by next generation sequencing (NGS), which identified allelic variant germline pathogenic c. 256C> T heterozygosis exon 1 gene. The is...