A5090792160- Acute Myocardial Infarction Research
- Hormonal Regulation and Hypertension
- Cardiac Fibrosis and Remodeling
- Protease and Inhibitor Mechanisms
- Menopause: Health Impacts and Treatments
- Estrogen and related hormone effects
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Nitric Oxide and Endothelin Effects
- MicroRNA in disease regulation
- Cardiac electrophysiology and arrhythmias
- Phytochemistry and Biological Activities
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular Syncope and Autonomic Disorders
- Platelet Disorders and Treatments
- Cardiovascular Effects of Exercise
- Heart Failure Treatment and Management
- NF-κB Signaling Pathways
- Pancreatitis Pathology and Treatment
- Cardiac Ischemia and Reperfusion
- Diabetes Treatment and Management
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
Yuhuangding Hospital
2007-2025
Qingdao University
2007-2025
Guangxi Normal University
2006
This case report describes a patient in his late 60s who presented to the emergency department with 3-month history of recurrent spontaneous chest tightness, palpitations, and syncope.
Context: Sophocarpine, a tetracyclic quinolizidine alkaloid, is one of the most abundant active ingredients in Sophora alopecuroides Linn. (Kudouzi). Sophocarpine injection was found to have significant antiviral effects against coxsackievirus B3 and therapeutic for viral myocarditis clinic.Objective: This study assessed sophocapine on overload-induced cardiac fibrosis investigated potential mechanisms.Materials methods: Adult male Sprague–Dawley rats were subjected suprarenal abdominal...
Abstract The relationship between endogenous estrogens and cardiovascular disease in menopausal women remains poorly understood. Studies examining the have yielded conflicting results. Therefore, we performed this study to prospectively assess effects of estrogen on risk myocardial no‐reflow postmenopausal with ST‐elevation infarction (STEMI). Consecutive 100 diagnosed STEMI who had undergone emergence percutaneous coronary intervention (PCI) were included study. Blood samples obtained...
Aldosterone plays an important role in the pathogenesis of non-familial atrial fibrillation (AF). We tested hypothesis that -344T/C polymorphism aldosterone synthase gene may be associated with AF Chinese patients hypertension.We performed a 1:1 paired case-control study 310 cases hypertension and same number matched controls. The was determined polymerase chain reaction-restriction fragment length polymorphism.The distribution CYP11B2 genotypes (TT, TC CC) 41.9%, 50.6%, 7.4% patients, which...
In myocardial ischemia‑reperfusion injury (MIRI), increased activity of the c‑Jun N‑terminal kinase (JNK) pathway and activation platelets that leads to formation platelet‑leukocyte aggregates (PLAs) have been observed. It was hypothesized ischemic postconditioning in MIRI exerts cardioprotective effects by altering JNK activity, which turn reduced PLA levels. A total 60 rats were randomly divided into 6 groups (n=10 for each group): i) Control; ii) alone; iii) with (PostC group), iv)...
<h3>Background</h3> Matrix metalloproteases (MMPs) have been implicated in the pathogenesis of acute myocardial infarction (AMI). However, little is known about association between MMP-9 and no-reflow. The aim this study was to evaluate role at infarct-related artery as a predictor no-reflow patients with ST-elevation AMI. <h3>Methods</h3> We prospectively enrolled 90 eligible AMI patients, undergoing successful primary PCI. Blood samples were obtained from extraction catheter placed distal...
<h3>Objective</h3> We investigated whether elevated levels of circulating platelet-leukocyte aggregates (PLA) can be used to identify acute myocardial infarction patients with no-reflow. <h3>Methods</h3> 120 (AMI) (72 male/48 female, mean age: 65.6 ± 8.6 years), undergoing successfully percutaneous coronary intervention (PCI), were studied and their PLA was measured by flow cytometry. identified as platelet-neutrophil (PNA) platelet-monocyte (PMA). No-reflow defined a TIMI grade ≤ 2 after...