Kefir-based fermentation products exhibit antioxidant and anti-inflammatory effects against oxidative stress, inflammation, platelet activation aggregation, other related manifestations, thereby preventing the onset development of several chronic diseases. Specifically, water kefir, a symbiotic culture various microorganisms used for production bio-functional fermented products, has been proposed its health-promoting properties. Thus, kefir grains apple pomace-based beverage were studied...

Lutein is particularly known to help maintain normal visual function by absorbing and attenuating the blue light that strikes retina in our eyes. The effect of overexposure on eyes due excessive use electronic devices becoming an issue modern society insufficient dietary lutein consumption through diet. There has, therefore, been increasing demand for lutein-containing supplements also food industry supplementation bakery products, infant formulas, dairy carbonated drinks, energy juice...

Apple pomace (AP) is a bio-waste product of apples that co-produced as by-product during apples' processing for making apple-based products, mainly apple juice, cider and vinegar. AP rich source several bioactives can be valorized ingredients developing novel functional foods, supplements nutraceuticals. Within the present study, food-grade extracts from with different tannin contents were found to contain bioactive polar lipids (PLs), phenolics carotenoids strong anti-oxidant,...

Abstract Background Pro-inflammatory processes triggered by the accumulation of extracellular amyloid beta (Aβ) peptides are a well-described pathology in Alzheimer's disease (AD). Activated astrocytes surrounding Aβ plaques contribute to inflammation secreting proinflammatory factors. While may phagocytize and clearance, reactive also increase production. Therefore, identifying factors that can attenuate astrocyte activation neuroinflammation how these influence pro-inflammatory pathways is...

Cyanobacteria and microalgae have been cultivated only for a limited number of bioactive compounds or biotechnological applications such as carotenoids; essential omega-3 fatty acids; phycobilipigments; live cells, unprocessed minimally processed complete biomass aqua feed, animal feed human health supplements rich sources proteins, carbohydrates, pigments, vitamins minerals. However, cyanobacteria reported through several research investigations potential source various molecules with...

Marine and salmon polar lipids (PLs) extracted by conventional extractions with non-food-grade solvents (CE-salmon-PLs) possess antithrombotic bioactivities against platelet-activating factor (PAF) thrombin. Similar effects of food-grade-extracted (FGE) marine PLs have not yet been reported. In this study, food-grade were used to extract from Irish organic farmed (Salmo salar) fillets (FGE-salmon-PLs), while their assessed in human platelets induced platelet aggregation agonists...

Microalgae are at the start of food chain, and many known producers a significant amount lipids with essential fatty acids. However, bioactivity microalgal for anti-inflammatory antithrombotic activities have rarely been investigated. Therefore, sustainable source above bioactive lipids, present study was undertaken. The total microalga Chlorococcum sp., isolated from Irish coast, were fractionated into neutral-, glyco-, phospho-lipids, tested in vitro their activities. All lipid fractions...

The characterization of cardio-protective lipid bioactives from cyanobacteria, such as Spirulina spp., has rarely been investigated. In this study, neutral lipids, glycolipids, and phospholipids Irish marine cyanobacterium subsalsa, were tested for anti-inflammatory antithrombotic activities in vitro human platelets. Glycolipids inhibited strongly platelet aggregation induced by platelet-activating factor (PAF) or thrombin, with IC50 (half maximal inhibitory concentration) values ranging...

Exclusion of combined nitrogen (NaNO3) from the growth medium caused certain changes in metabolic processes leading to cessation non-heterocystous, non nitrogen-fixing marine cyanobacterium Oscillatoria willei BDU 130511. But antioxidative enzymes, namely superoxide dismutase and peroxidase, helped organism survive stress. Prominent effects observed during starvation/limitation were: (i) reduction major accessory photosynthetic pigments, (ii) impairment photosynthesis due loss one Rubisco...

While several marine polar lipids (PL) have exhibited cardioprotective properties through their effects on the platelet-activating factor (PAF) pathways, salmon PL not been tested so far. In this study, antithrombotic activities of were assessed in human platelets and structural characterisation bioactive was performed by GC-MS LC-MS analyses. from fillets Irish organic farmed (Salmo salar) extracted separated into lipid subclasses thin-layer chromatography (TLC), while fatty acid profile...

The present study evaluated 53 Irish marine cyanobacteria intending to identify potential producers of mycosporine-like amino acids (MAAs) meet the increasing demand for replacing chemical sunscreen with bio-sunscreen. biodiscovery analysis using absorption spectra methanolic extracts identified eight as MAAs a specific content 0.114–0.511 A* mg DW−1. Leptolyngbya tenuis SABC010201 was found possess notably higher content. LC-MS total different types known (mycosporine-glutamicol,...

Chondroitin sulphates (CSs) are the most well-known glycosaminoglycans (GAGs) found in any living organism, from microorganisms to invertebrates and vertebrates (including humans), provide several health benefits. The applications of CSs numerous including tissue engineering, osteoarthritis treatment, antiviral, cosmetics, skincare applications. current commercial production mostly uses animal, bovine, porcine, avian tissues as well marine organisms, mammals, sharks, other fish. process...

Fish contains bioactive polar lipids (PL) and is mainly consumed cooked. The aim of this study was to evaluate the sensory characteristics sous-vide cooked salmon in vitro cardio-protective properties its PL. PL were extracted from brined un-brined preparations 52 °C, 65 80 while their antithrombotic assessed human platelets fatty acid (FA) content evaluated by LC-MS. Sensory tests performed using napping followed check-all-that apply (CATA). Mild temperatures (52 °C) did not affect...

The structures of bioactive polar lipids (PLs) Irish ale with potent antithrombotic and cardioprotective properties were elucidated. Ale PL was fractionated by preparative thin layer chromatography (TLC) into subclasses, their effect assessed against human platelet aggregation induced the pro-inflammatory mediator, platelet-activating factor (PAF). fatty acid content overall elucidated liquid mass spectrometry (LC-MS). Phosphatidylcholines (PC) molecules sphingomyelin (SM) family exhibited...

The antioxidant, antithrombotic and anti-inflammatory effects of the amphiphilic compounds extracted from both avocado juice by-products, were evaluated. All extracts assessed for their total phenolic content (TPC) carotenoid (TCC), antioxidant activities by DPPH, ABTS FRAP assays as well potency in human platelets. rich TAC (Total Amphiphilic Content) showed much higher phenolics carotenoids lipophilic (TLC), which was reflected stronger capacities extracts. ATR-FTIR spectroscopy revealed...

The anti-inflammatory, antithrombotic and antioxidant effects of extracts from both apple juice by-products (apple pomace) organic cultured Greek Starking apples were evaluated in vitro. All separated their total amphiphilic compounds (TACs) lipophilic (TLCs) assessed for phenolic content (TPC), carotenoid (TCC) activities (by the DPPH, ABTS FRAP assays), as well anti-inflammatory potency against thrombo-inflammatory mediator, platelet activating factor (PAF) a standard platelet-agonist...