A5060449181- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Airway Management and Intubation Techniques
- Cardiac and Coronary Surgery Techniques
- Anesthesia and Pain Management
- Cardiac Valve Diseases and Treatments
- Anesthesia and Sedative Agents
- Aortic aneurysm repair treatments
- Coffee research and impacts
- Respiratory Support and Mechanisms
- Congenital Heart Disease Studies
- Lipoproteins and Cardiovascular Health
- Intensive Care Unit Cognitive Disorders
- Nausea and vomiting management
- Heart Rate Variability and Autonomic Control
- Global Health and Surgery
- Vitamin K Research Studies
- Health and Medical Research Impacts
- Cardiac Ischemia and Reperfusion
- Aortic Disease and Treatment Approaches
- Tracheal and airway disorders
- Cardiovascular Health and Disease Prevention
- Adipokines, Inflammation, and Metabolic Diseases
- Drug-Induced Adverse Reactions
- Venous Thromboembolism Diagnosis and Management
Institute of Cardiology
2012-2025
Universidad del Rosario
2001-2019
Infant Foundation
2012
Caffeine is the most widely consumed stimulating substance in world. It found coffee, tea, soft drinks, chocolate, and many medications. a xanthine with various effects mechanisms of action vascular tissue. In endothelial cells, it increases intracellular calcium production nitric oxide through expression synthase enzyme. Nitric diffused to smooth muscle cell produce vasodilation. cells its effect predominantly competitive inhibition phosphodiesterase, producing an accumulation cAMP...
Objective: To determine the prognostic relevance, clinical characteristics, and 30-day outcomes associated with myocardial injury after noncardiac surgery (MINS) in vascular surgical patients. Background: MINS has been independently mortality surgery. The characteristics importance of patients are poorly described. Methods: This was an international prospective cohort study 15,102 45 years or older, whom 502 underwent All had fourth-generation plasma troponin T (TnT) concentrations measured...
Although early tracheal extubation in cardiac anesthesia is safe and cost beneficial, questions still remain regarding how after surgery patients should be tracheally extubated (TE). Our objective was to determine the effects on resource use if scheduled for coronary artery bypass grafting have TE operating room (OR). We studied 100 consecutive undergoing elective grafting, requiring extracorporeal circulation, those eligible a fast-track pathway. At end of procedure, were evaluated OR they...
BACKGROUND Simultaneous liver-kidney transplantation (SLKT) is a complex procedure essential for patients with end-stage liver and kidney disease. Most SLKT outcome reports originate from large transplant centers in developed countries, limited data Latin America. This study aimed to describe outcomes at high-complexity center Colombia assess their comparability existing literature. MATERIAL AND METHODS A retrospective, single-center included adult pediatric who underwent between January...
Heparin requires antithrombin III (AT) to achieve anticoagulation, and patients on continuous small-dose heparin preoperatively experience decreased levels of AT-causing resistance. When this occurs, 2-4 units fresh frozen plasma ( approximately 1000 AT) are often administered increase AT restore responsiveness. We evaluated purified human concentrate (Thrombate III; Bayer, Inc., Elkhart, IN) in vitro anticoagulation responses receiving heparin. Blood samples were obtained from cardiac...
BACKGROUND: Two trials reported that a high inspiratory oxygen fraction (F io 2 ) does not promote myocardial infarction or death. Observational studies can provide larger statistical strength, but associations be due to unobserved confounding. Therefore, we evaluated the association between intraoperative F and cardiovascular complications in large international cohort study see if spurious were observed. METHODS: We included patients from Vascular events In noncardiac Surgery patIents...
The efficacy of protective ventilation in acute lung injury has validated its use the operating room for patients undergoing thoracic surgery with one-lung (OLV). purpose this study was to investigate effects two different modes using low tidal volumes: pressure controlled (PCV) vs. volume (VCV) on oxygenation and airway pressures during OLV. We studied 41 scheduled thoracoscopy surgery. After initial two-lung VCV were randomly assigned one groups. In group OLV started (tidal 6 mL/kg, PEEP...
Abstract Background Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome is a severe adverse drug reaction marked by delayed hypersensitivity reactions causing skin systemic complications. DRESS diagnosis challenging due to the variety of clinical presentations symptom overlap other conditions. The perioperative period in these patients requires precise pharmacological strategies prevent complications associated this syndrome. treatment induced unfractionated heparin during...
Background Vasospasm of arterial grafts represents an unpredictable complication coronary artery surgery and may compromise myocardial revascularization, treatment is based on empirical therapy with nitroglycerin. Because the potential for tolerance to nitroglycerin occur, authors studied different vasodilators acting through separate pathways segments human internal mammary artery. Methods Isolated vascular rings were precontracted norepinephrine (1 microM), KCl, or thromboxane A2 analogue...
La práctica clínica perioperatoria en Latinoamérica está influenciada por investigación generada y publicada países desarrollados. Afortunadamente, las condiciones económicas cada vez más favorables para la ciencia los vías de desarrollo, sumado al incremento visibilidad nuestras publicaciones científicas, han desencadenado un el interés mejorar estándares calidad local a su trabajos grado que se generan durante estudios posgrado anestesiología. El presente documento es resultado...
In low- and middle-income countries emergency surgery represents a higher proportion of the total number surgeries is associated with greater morbidity/mortality. Study aims were to determine if department length stay (ED-LOS) was adverse perioperative outcomes such association varied across patient's risk categories. A retrospective cohort study conducted adult patients who underwent orthopedic or abdominal at two Colombian University hospitals. The population comprised mix representative...
INTROduCTIONPatients undergoing vascular procedures are prone to developing postoperative complications affecting their short -term mortality.Prospective reports describing the incidence of long after surgery lacking.ObjECTIvEs We aimed describe 1 year and evaluate an association between myocardial injury noncardiac (MINS) -year mortality.PATIENTs ANd mEThOds This is a substudy large prospective cohort study Vascular Events in Noncardiac Surgery Patients Cohort Evaluation...
Perioperative clinical practice in Latin America is influenced by research developed and published countries. Fortunately, the increasingly favorable economic conditions for science developing countries, addition to heightened visibility of our scientific publications has triggered greater interest improving quality standards local graduate theses generated course studies anesthesiology. This document result active participation discussion among speakers attending "Symposium on Research...
Choosing a cardioplegic solution is significant issue in modern cardiac surgery. Although different options are available, the optimal strategy for myocardial protection has not been established. The aim of this study was to compare intraoperative and postoperative effects histidine-tryptophan-ketoglutarate (HTK) with those standard blood cardioplegia St Thomas No 2 solution. conducted using large cohort adult patients undergoing complex surgery.This single center retrospective review...
Levosimendan, an inotropic drug that enhances myocardial contractility through myofilment calcium sensitazion, induces peripheral vasodilation via opening ATP-dependent K(+) channels. It is unknown whether this can be used for the treatment of perioperative vasospasm arterial conduits coronary artery bypass grafting.We investigated effects levosimendan on human internal mammary (IMA) specimens taken from patients undergoing surgery. The rings were carefully prepared and placed between two...