Masahiro SUGIYAMA

ORCID: 0000-0002-4024-0805
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About
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Research Areas
  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • Hypothalamic control of reproductive hormones
  • Medical Imaging and Pathology Studies
  • Proteins in Food Systems
  • Asthma and respiratory diseases
  • Infectious Diseases and Mycology
  • Diphtheria, Corynebacterium, and Tetanus
  • Viral gastroenteritis research and epidemiology
  • Cancer-related molecular mechanisms research
  • Medical Imaging Techniques and Applications
  • Clostridium difficile and Clostridium perfringens research
  • Microbial infections and disease research
  • Mycobacterium research and diagnosis
  • Pediatric health and respiratory diseases
  • Immune Response and Inflammation
  • Stress Responses and Cortisol
  • Inflammasome and immune disorders
  • Nasolacrimal Duct Obstruction Treatments
  • Veterinary medicine and infectious diseases
  • Endoplasmic Reticulum Stress and Disease
  • Animal Virus Infections Studies
  • melanin and skin pigmentation
  • Colorectal Cancer Treatments and Studies

Fuji Oil (Japan)
2022-2024

Japan Organization of Occupational Health and Safety
2023

Ichikawa City Rehabilitation Hospital
2020

Hokkaido University
2013-2018

Hamamatsu University
2018

National Center for Global Health and Medicine
2013

Center for Global Health
2013

Genomics Research Center, Academia Sinica
2013

Nagoya City University
2010

Hôpital Saint Joseph
2010

The 2-year prognosis of malignant mammary tumors seen in 175 bitches the Tokyo metropolitan area was assessed based on their TNM clinical staging and histological classification. larger tumor size became (T category), poorer prognosis. survival rates animals with regional lymph node metastasis cells (N1, N2 category) and/or distant (M1 were markedly lower than those without such involvement. As grade increased, poorer, however, there no significant differences among subtypes adenocarcinomas...

10.1292/jvms.58.11_1079 article EN Journal of Veterinary Medical Science 1996-01-01

ABSTRACT Aichi viruses isolated in Vero cells from seven patients five gastroenteritis outbreaks Japan, Japanese returning Southeast Asian countries, and local children Pakistan with were examined for differentiation based on their reactivities a monoclonal antibody to standard strain (A846/88) reverse transcription-PCR (RT-PCR) of three genomic regions. The RNA sequences determined 519 bases these 17 isolates at the putative junction between C terminus 3C N 3D. analyses revealed an...

10.1128/jcm.38.8.2955-2961.2000 article EN Journal of Clinical Microbiology 2000-08-01

Interleukin-1β (IL-1β) plays crucial roles in the pathogenesis of periodontal disease. It is produced after processing pro-IL-1β by caspase-1, which activated inflammasome-a multiprotein complex comprising nucleotide-binding domain leucine-rich repeat-containing receptor (NLR), adaptor protein apoptosis-associated speck-like containing a caspase-recruitment (ASC), and procaspase-1. Mycoplasma salivarium preferentially inhabits gingival sulcus incidence number organisms oral cavity increase...

10.1111/omi.12117 article EN Molecular Oral Microbiology 2015-07-14

Assessment of Gadolinium-Enhanced Time-Resolved Three-Dimensional MR Angiography for Evaluating Renal Artery StenosisHatsuko Masunaga1, Yasuo Takehara1, Haruo Isoda1, Tatsuya Igarashi1, Masahiro Sugiyama1, Satoshi Isogai1, Nami Kodaira1, Hiroyasu Takeda1, Atsushi Nozaki2 and Harumi Sakahara1Audio Available | Share

10.2214/ajr.176.5.1761213 article ID American Journal of Roentgenology 2001-05-01

The purpose of this study was to evaluate the clinical performance newly implemented dynamic MR dacryocystography.Dynamic dacryocystography, which requires neither ionizing radiation nor chemical contrast media with high viscosity, may be a useful tool for depicting nasolacrimal obstructions.

10.2214/ajr.175.2.1750469 article EN American Journal of Roentgenology 2000-08-01

40 haemodynamically unstable patients with pelvic injuries were studied to assess the ability of plain radiographs detect haemorrhagic sites. Pelvic and bilateral angiograms reviewed separately for detection sites in both anterior posterior segments. Sensitivity specificity obtained by analysis angiographic findings. Angiography demonstrated arterial injury 106 divisions: 26 right anterior, 22 posterior, 33 left 25 posterior. Sensitivities predicting higher segment (right, 96%; left, 100%)...

10.1259/bjr.73.873.11064646 article EN British Journal of Radiology 2000-09-01

Summary The NLRP3 inflammasome, an intracellular sensor consisting of the nucleotide‐binding oligomerization domain‐like receptor family, pyrin domain containing 3 (NLRP3), adaptor protein apoptosis‐associated speck‐like a caspase‐recruitment (ASC), and procaspase‐1, plays critical roles in host defense against microbial pathogens by inducing production interleukin‐1β (IL‐1β) IL‐18. Mycoplasma salivarium pneumoniae cells activated murine bone marrow‐derived macrophages (BMMs) to induce...

10.1111/omi.12225 article EN Molecular Oral Microbiology 2018-04-23

The performance of a newly developed potential tumor-seeking magnetic resonance (MR) contrast agent alpha-Aqua-13,17-bis(1-carboxypropionyl) carbamoylethyl-3,8-bis(1-phenethyloxyethyl)-beta-hydroxy-2,7,12,18-tetramethyl-porphyrinato manganese (III) (HOP-8P) was tested using mouse model. Tumor-bearing (SCC-VII) mice were imaged 1.5T MR imager before and after intravenous administration 0.1 mmol/kg HOP-8P. A biodistribution analysis performed an optical emission spectrometer. Significant...

10.1002/mrm.10109 article EN Magnetic Resonance in Medicine 2002-02-20

We report an unusual case of perforation a congenital fibrosarcoma the jejunum in utero and secondary meconium peritonitis. Prenatal ultrasound showed polyhydramnios fetal ascites from 25 gestational weeks absence other anomalies. A 2200 g baby girl was born at 34 gestation, presenting with severe generalized edema respiratory distress immediately after birth. Plain radiography revealed progressive abdominal distension pneumoperitoneum. The subsequently underwent surgery age one day. upper...

10.1055/s-2003-39560 article EN European Journal of Pediatric Surgery 2003-04-01

The clinical usefulness of biodegradable oriented poly-L-lactide (PLLA) screws for experimental Salter-Harris type 4 fracture in the distal femoral condyle dogs was evaluated. Bony union osteotomized fragment almost completed radiographically and histologically within 1 to 2 months after surgery, suggesting that PLLA maintained strength long enough fix until bone healing. At 6 minute fissures were confirmed on surface screw thread, early stage biodegradation absorption polymer. During...

10.1292/jvms.56.817 article EN Journal of Veterinary Medical Science 1994-01-01

Two existing approaches facilitate the understanding of role soy protein in maintaining soybean product quality: first involves separation major fractions from seeds via various techniques, whereas second compares products made several varieties with different contents and compositions. In this study, we developed a novel method fractionating total proteins determining composition seeds. A high-salt concentration solution was used to extract whole non-defatted powder. The separated into four...

10.1016/j.focha.2022.100115 article EN cc-by Food Chemistry Advances 2022-10-01

Abstract Selecting suitable soybean cultivars is important for food processing and exploring their endowment with desirable physiological functions. We applied the fractionation method previously established to compare soy protein composition among promote such a selection. More than 95% of proteins in cotyledons were extracted from 13 using high‐concentration salt solution. The fractionated into five fractions, namely oil body‐associated (OBAP), polar lipid‐associated (PLAP), globulins (11S...

10.1002/aocs.12725 article EN Journal of the American Oil Chemists Society 2023-07-12

Right-to-left shunts of pulmonary arteriovenous malformation (PAVM) can be detected and measured by perfusion scans using Tc-99m MAA. In PAVM with a relatively small right-to-left shunt, however, measurement the shunt ratio may not reliable. This study re-evaluated for PAVM.Tc-99m MAA lung were performed in five patients proved before after percutaneous transcatheter embolization. The was calculated extrapulmonary uptake assessed on total-body images.Lung obtained embolization revealed brain...

10.1097/00003072-200109000-00003 article EN Clinical Nuclear Medicine 2001-09-01

Transverse diaphyseal fractures of the femur were experimentally made in immature cats, and fixed by an intramedullary pinning technique using uniaxially oriented poly-L-lactide (PLLA) rod, a biodegradable polymer. The healing process was evaluated radiographically histologically. Formation bony callus completed 8 weeks, cortical union followed. remodeling then observed form 12 to 16 weeks. almost same as when metallic implant used. Abundant periosteal formation may be attributable lower...

10.1292/jvms.56.1041 article EN Journal of Veterinary Medical Science 1994-01-01

Many papers have reported the effect of amphetamine and its close relative, methamphetamine on sexual activity in humans. The these drugs animal behavior is unknown. present study was done to determine whether modifies copulatory male rats. Sexually experienced rats Wistar-Imamichi strain, 10 weeks age, were singly injected intraperitoneally with hydrochloride at doses 0, 1, 2 or 4 mg/kg body weight. Tests initiated 19: 30 dark period. Observations conducted for 90 min. At dosages 1 there no...

10.1538/expanim1978.40.4_447 article EN EXPERIMENTAL ANIMALS 1991-01-01

This study was designed to determine whether oral streptococci modulate the growth and functions of regulatory T cells. Heat-killed cells wild-type strains Streptococcus gordonii mutans induced Toll-like receptor 2 (TLR2) -mediated nuclear factor-κB (NF-κB) activation, but their lipoprotein-deficient did not. Stimulation with these resulted in a significant increase frequency CD4(+) CD25(+) Foxp3(+) splenocytes derived from both TLR2(+/+) TLR2(-/-) mice, level stronger than that splenocytes....

10.1111/omi.12023 article EN Molecular Oral Microbiology 2013-01-04
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