Yoshio Shima

ORCID: 0000-0003-2287-4430
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Preterm Birth and Chorioamnionitis
  • Congenital Diaphragmatic Hernia Studies
  • Neuroscience of respiration and sleep
  • Reproductive System and Pregnancy
  • Congenital Heart Disease Studies
  • Neonatal and Maternal Infections
  • Neonatal and fetal brain pathology
  • Infant Development and Preterm Care
  • Cardiovascular Issues in Pregnancy
  • Pregnancy and preeclampsia studies
  • Tracheal and airway disorders
  • Streptococcal Infections and Treatments
  • Gestational Trophoblastic Disease Studies
  • Immune Response and Inflammation
  • Respiratory Support and Mechanisms
  • Assisted Reproductive Technology and Twin Pregnancy
  • Ocular Diseases and Behçet’s Syndrome
  • Infant Nutrition and Health
  • Digital Transformation in Industry
  • Cardiac Arrhythmias and Treatments
  • Pediatric Hepatobiliary Diseases and Treatments
  • Congenital Anomalies and Fetal Surgery
  • Cardiovascular Effects of Exercise
  • Vascular anomalies and interventions

Nippon Medical School Musashi Kosugi Hospital
2013-2025

Nippon Medical School
2013-2024

Kobe City Medical Center General Hospital
2021-2022

Japanese Red Cross Katsushika Maternity Hospital
2002-2021

Yokohama City University
2003

Japanese Red Cross Medical Center
1993-2000

Toyota Industries (Japan)
1985

Fulminant type 1 diabetes mellitus (fulminant T1DM) can progress rapidly to diabetic ketoacidosis (DKA). It develop in pregnant women with no prior history of diabetes, and such cases are associated severe perinatal consequences. We report the detailed clinical course a neonate born from mother DKA caused by fulminant T1DM. The male weighed 3,024 grams was at 36 weeks gestation. patient's had an uneventful pregnancy until she visited hospital on day delivery headache, nausea, decreased fetal...

10.1272/jnms.jnms.2025_92-201 article EN Journal of Nippon Medical School 2025-04-20

Problem Acute chorioamnionitis ( aCAM ) is an important cause of pre‐term birth. However, little known about the pathogenesis late birth without that was most common category Here we analyze kinetics immune cells obtained from decidua women with births and . Method study Deciduas were who underwent labor PB ‐n/ or ‐w/ ). The population DEC ‐205 + dendritic DC s), macrophages, invariant natural killer T iNKT cells, NK CD 8 4 analyzed by flow cytometry. Results number higher in than s...

10.1111/aji.12658 article EN American Journal of Reproductive Immunology 2017-03-09

Infants born in Japan are reported to have a low incidence of necrotizing enterocolitis (NEC) among countries, and these differences remained significant after adjusting for common clinical factors. To investigate the impact ethnic background, we compared NEC between infants those mothers Japanese ethnicity California. Preterm 2008 2019 at 22–29 weeks gestational age were analyzed retrospectively. Four groups analyzed: (JP), California (JP-J), with but United States or another country...

10.1038/s41598-025-92393-y article EN cc-by-nc-nd Scientific Reports 2025-03-22

In this case-control study, we examined infants delivered vaginally at 37 weeks or later to identify factors associated with transient tachypnea of the newborn (TTN). We reviewed obstetric records all vaginal deliveries Japanese Red Cross Katsushika Maternity Hospital from 2005 through 2007. Demographic information and characteristics labor were extracted patient charts. Multivariate analysis identified that incidence TTN was significantly nulliparity; a history infertility therapy, such as...

10.1272/jnms.75.269 article EN Journal of Nippon Medical School 2008-01-01

The aim of the study was to determine factors that affect adverse long-term pulmonary outcome in premature infants.This retrospective analysis done using 306 clinical records preterm singleton neonates at <32 weeks gestation. Two definitions were used: chronic lung disease (CLD), defined as a need for supplemental oxygen least 28 days after birth; and bronchopulmonary dysplasia (BPD), dependency birth plus 36 postmenstrual age and/or positive-pressure ventilatory support. Selected perinatal...

10.1111/ped.12151 article EN Pediatrics International 2013-06-10

Abstract Aim: Chronic lung disease (CLD) is a major component in the morbidity of premature infants suffering from fetal inflammatory response (FIRS). The aim present study was to compare value measuring neonatal urinary β 2 ‐microglobulin (β ‐MG) levels with blood interleukin (IL)‐6 at risk developing CLD. Methods: Premature (gestational age &lt;30 weeks) without CLD ( n = 19) and 10) were enrolled. We measured IL‐6 umbilical cord ‐MG urine obtained within 48 h after birth. Results:...

10.1111/j.1447-0756.2008.00988.x article EN Journal of Obstetrics and Gynaecology Research 2009-06-01

We describe an infant with nemaline myopathy accompanied by hypertrophic cardiomyopathy. The patient required long-term, intermittent positive-pressure ventilation after birth owing to muscle weakness, and cardiac failure developed during infancy. diagnosed cardiomyopathy outflow tract obstruction, treated the heart β-adrenergic angiotensin II receptor blockers. discuss prognosis of combined

10.1272/jnms.75.350 article EN Journal of Nippon Medical School 2008-01-01

Abstract We present a rare case of suprasellar arachnoid cyst discovered incidentally on routine fetal sonographic examination. Serial and MRI scanning led to prenatal diagnosis appropriate endoscopic treatment at 5 months age. The patient is currently developing normally 3 years Careful screening intracranial abnormalities important in examination for early intervention, which will prevent irreversible complications such as endocrine disorders visual impairment. © 2006 Wiley Periodicals,...

10.1002/jcu.20202 article EN Journal of Clinical Ultrasound 2006-02-01

We present here a case of massive subchorionic hematoma complicated by intrauterine growth retardation and oligohydramnios diagnosed at 22 weeks' gestation. The patient was managed with the following medications: (1) tocolysis ritodrine infusion, (2) 10%maltose infusion therapy (1500mL/day), (3) antibiotic (cefotaxim sodium, 2 g/day×7) (4) kampo Sairei-to until delivery. At 33 weeks 0 days' gestation, female baby weighing 1,342 g delivered without complication caesarean section. During...

10.1272/jnms.68.54 article EN Journal of Nippon Medical School 2001-01-01

We report an unusual case of perforation a congenital fibrosarcoma the jejunum in utero and secondary meconium peritonitis. Prenatal ultrasound showed polyhydramnios fetal ascites from 25 gestational weeks absence other anomalies. A 2200 g baby girl was born at 34 gestation, presenting with severe generalized edema respiratory distress immediately after birth. Plain radiography revealed progressive abdominal distension pneumoperitoneum. The subsequently underwent surgery age one day. upper...

10.1055/s-2003-39560 article EN European Journal of Pediatric Surgery 2003-04-01

Problem Acute chorioamnionitis (aCAM) associated with microbial infection is a primary cause of preterm birth (PB). However, recent studies have demonstrated that innate immunity and sterile inflammation are causes PB in the absence aCAM. Therefore, we analyzed immune cells decidua early to moderate without Method study Deciduas were obtained from patients at gestational age 24 +0 33 +6 weeks aCAM pathological diagnosis. The divided into two groups as follows: labor and/or rupture membrane...

10.1111/aji.13330 article EN American Journal of Reproductive Immunology 2020-09-02

Zinc (Zn), an essential trace element, plays a significant role in fetal development and biological defense during the embryonic neonatal periods. Therefore, exploring kinetics of Zn related to immune disturbances preterm neonates is important. We here performed measurement concentration along with immunological analysis investigated period. Serum concentrations were measured immediately after birth (329 cases). Moreover, for 25 cases, various cells cytokines by flow cytometry...

10.1080/25785826.2024.2420426 article EN cc-by-nc Immunological Medicine 2024-10-25

Anhidrotic ectodermal dysplasia (AED) is a rare hereditary disorder with triad of sparse hair, dental hypoplasia, and anhidrosis. Here we report case AED food allergy atopic eczema. The patient was 11-month-old boy admitted to our hospital pyrexia for 2 weeks. He presented history dry skin, eczema, egg. On clinical examination, his body temperature 38.8°C, skin eczema almost all over the body, eyebrows, scalp hair. Laboratory investigations physical examination did not show any evidence...

10.5415/apallergy.2019.9.e3 article EN cc-by-nc Asia Pacific Allergy 2019-01-01

Fetal inflammatory response syndrome (FIRS), which induces hypercytokinemia, is important for the outcomes of premature infants. It necessary to focus on fetal environments.A total 37 infants (gestational age ≤32 weeks) were divided into three groups: (1) 15 without chorioamnionitis (CAM) and funisitis; C(-)F(-) group, (2) with CAM but C(+)F(-) group (3) 7 C(+)F(+) group. Blood interleukin (IL)-1β, IL-6 IL-8 levels measured day 0 (= in umbilical cord blood), 3, 7, 14, 21 28.(1) 0: Cord blood...

10.3109/14767058.2013.867321 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2013-11-19
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