Si‐Jia Chen

ORCID: 0000-0002-4081-0134
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Nonlinear Photonic Systems
  • Nonlinear Waves and Solitons
  • Acupuncture Treatment Research Studies
  • Algebraic structures and combinatorial models
  • Hepatitis B Virus Studies
  • Structural Behavior of Reinforced Concrete
  • Advanced Mathematical Physics Problems
  • Liver Disease Diagnosis and Treatment
  • Structural Load-Bearing Analysis
  • Hepatitis C virus research
  • Advanced Fiber Laser Technologies
  • Viral Infectious Diseases and Gene Expression in Insects
  • Cancer survivorship and care
  • Natural product bioactivities and synthesis
  • Vagus Nerve Stimulation Research
  • Virus-based gene therapy research
  • Cancer Mechanisms and Therapy
  • Plant Toxicity and Pharmacological Properties
  • Genomics, phytochemicals, and oxidative stress
  • Gut microbiota and health
  • Diet and metabolism studies
  • Autophagy in Disease and Therapy
  • Fractional Differential Equations Solutions
  • HIV Research and Treatment
  • Childhood Cancer Survivors' Quality of Life

Shanghai Jiao Tong University
2014-2025

Fudan University
2014-2025

Huashan Hospital
2022-2025

State Key Laboratory of Medical Neurobiology
2022-2025

Wenzhou Medical University
2017-2025

First Affiliated Hospital of Wenzhou Medical University
2017-2025

Southeast University
2024

Zhejiang Chinese Medical University
2022-2024

Jiaxing University
2007-2024

Tianjin Medical University
2024

10.1016/j.cnsns.2023.107205 article EN Communications in Nonlinear Science and Numerical Simulation 2023-03-07

Abstract In this paper, we propose a combined form of the bilinear Kadomtsev–Petviashvili equation and extended (2+1)-dimensional shallow water wave equation, which is linked with novel nonlinear model. This model might be applied to describe evolution waves in ocean. Under effect combination nonlinearity dispersion terms, two cases lump solutions are derived by searching for quadratic function form. Moreover, one-lump-multi-stripe constructed test combining functions multiple exponential...

10.1088/1572-9494/acc6b8 article EN Communications in Theoretical Physics 2023-03-23

We focus on the localized characteristics of lump and interaction solutions to two extended Jimbo–Miwa equations. Based Hirota bilinear method test function method, we construct exact equations including solutions, lump–kink other types by solving under-determined nonlinear system algebraic for associated parameters. Finally, analysis graphical simulation are presented show dynamical our behaviors revealed.

10.1088/1674-1056/aba9c4 article EN Chinese Physics B 2020-07-28

Abstract The N -rational solutions to two (2+1)-dimensional nonlinear evolution equations are constructed by utilizing the long wave limit method. M -lump derived making some parameters conjugate each other. We present and discuss 1-, 2- 3-lump equations. amplitude shape of one lump remain unchanged during propagation. dynamic properties collisions among multiple waves analyzed, which indicate that fusion fission might occur. merge into wave, then split waves. lines follow various if we...

10.1088/1402-4896/abf307 article EN Physica Scripta 2021-03-29

10.1016/j.cnsns.2021.105939 article EN Communications in Nonlinear Science and Numerical Simulation 2021-07-15

10.1016/j.cnsns.2021.106103 article EN Communications in Nonlinear Science and Numerical Simulation 2021-12-14

There is emerging evidence that diet plays a key contributor to brain health, however, limited studies focused on the association of dietary inflammatory potential with disorders. This study aimed examine inflammation disorders in UK biobank. The prospective cohort used data from 2006 2010 Biobank, median follow-up duration for different outcomes ranging between 11.37 11.38. Dietary index and Energy-adjusted [DII EDII] were assessed through plausible recalls. Outcomes included (all-cause...

10.1038/s41398-025-03297-4 article EN cc-by-nc-nd Translational Psychiatry 2025-03-27

Diabetic nephropathy (DN) is one of the most common and serious chronic complications diabetes mellitus, however, no efficient clinical drugs exist for treatment DN. We selected synthesized several sesquiterpene lactones (SLs), then used MTT assay to detect rat mesangial cells (MCs) proliferation, ELISA measure expression level monocyte chemoattractant protein-1 (MCP-1), transforming growth factor beta (TGF-β1) fibronectin(FN), real-time fluorescent quantitative PCR analysis MCP-1 TGF-β1...

10.3390/molecules181013061 article EN cc-by Molecules 2013-10-21

Matrix attachment regions (MARs) are cis-acting DNA elements that can increase transgene expression levels in a CHO cell system. To investigate the effects of MAR combinations on and underlying regulatory mechanisms, we generated constructs which enhanced green fluorescent protein (eGFP) gene flanked by different human β-interferon β-globin (iMAR gMAR, respectively), was driven cytomegalovirus (CMV) or simian virus (SV) 40 promoter. These were transfected into CHO-K1 cells, screened with...

10.1038/srep42805 article EN cc-by Scientific Reports 2017-02-20

Vitamin A deficiency (VAD) plays an essential role in the pathogenesis of Alzheimer's disease (AD). However, specific mechanism by which VAD aggravates cognitive impairment is still unknown. At intersection microbiology and neuroscience, gut-brain axis undoubtedly contributing to formation function neurological systems, but most previous studies have ignored influence gut microbiota on VAD. Therefore, we assessed effect AD pathology decline model mice determined played intestinal process....

10.3389/fnagi.2021.753351 article EN cc-by Frontiers in Aging Neuroscience 2021-11-01

Abstract Circadian rhythm disruption (CRD) is a shared characteristic of various brain disorders, such as Alzheimer’s disease (AD), Parkinson’s (PD), and major depression disorder (MDD). Disruption circadian might be risk factor for incidents. From 7-day accelerometry data 72,242 participants in UK Biobank, we derived relative amplitude variable, which to some extent reflected the degree disruption. Records incidents were obtained from wide range health outcomes across self-report, primary...

10.1038/s41398-022-02278-1 article EN cc-by Translational Psychiatry 2022-12-14

This study explores the unmet psychosocial rehabilitation needs of cancer survivors.Sixty-eight survivors from Shanghai Cancer Rehabilitation Club in China participated one eight focus groups. These were transcribed verbatim, coded using thematic analysis and analysed NVivo 10.Five main themes identified: need for (1) better information: Chinese find it difficult to sort evaluate overwhelming mass information with which they are confronted; (2) psychological support: fear relapse neighbours'...

10.1002/pon.4023 article EN Psycho-Oncology 2015-11-03

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and arthritic pain. Sinomenine (SIN), derived from the rhizome of Chinese medical herb Qing Teng (scientific name: Sinomenium acutum (Thunb.) Rehd. Et Wils), has longstanding use in traditional medicine for treating rheumatoid arthritis. It been shown to possess anti-inflammatory, analgesic, immunosuppressive effects with minimal side-effects clinically. However, mechanisms governing its...

10.1016/j.jep.2024.117704 article EN cc-by-nc-nd Journal of Ethnopharmacology 2024-01-03

The optimal bit-width for achieving the best trade-off between quantized model size and accuracy has been a subject of ongoing debate. While some advocate 4-bit quantization, others propose that 1.58-bit offers superior results. However, lack cohesive framework different bits left such conclusions relatively tenuous. We present ParetoQ, first unified facilitates rigorous comparisons across 1-bit, 1.58-bit, 2-bit, 3-bit, quantization settings. Our findings reveal notable learning transition 2...

10.48550/arxiv.2502.02631 preprint EN arXiv (Cornell University) 2025-02-04
Coming Soon ...