A5102933283- Advancements in Transdermal Drug Delivery
- Phytoestrogen effects and research
- Advanced Drug Delivery Systems
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Bone Tissue Engineering Materials
- Nanoparticle-Based Drug Delivery
- biodegradable polymer synthesis and properties
- Proteins in Food Systems
- Pharmacological Effects of Natural Compounds
- Drug Solubulity and Delivery Systems
- Fatty Acid Research and Health
- Surfactants and Colloidal Systems
- Plant-based Medicinal Research
- Polymer Science and Applications
- Graphene research and applications
- Catalytic Processes in Materials Science
- Metal complexes synthesis and properties
- Dental Implant Techniques and Outcomes
- Facial Rejuvenation and Surgery Techniques
- Synthesis and biological activity
- Pharmacology and Obesity Treatment
- Ginkgo biloba and Cashew Applications
- Sperm and Testicular Function
- Curcumin's Biomedical Applications
Anhui University of Traditional Chinese Medicine
2003-2015
Anhui University
2010
The main purpose of this study was to prepare puerarin microemulsion system improve oral bioavailability puerarin. formulations were prepared using soybean oil, lecithin/ethyl lactate (1:1), and 1,2-propanediol/water. presence regions investigated by pseudo-ternary phase diagrams. droplet size characterized photo-correlation spectroscopy. In vivo pharmacokinetic conducted in mice, the results indicated that AUC0→∞ 15.82-fold higher than suspension upon administration. Particles round...
This study investigated the potential of targeted intestinal lymphatic transport puerarin via a lipid formulation approach. Three formulations PEG nanoemulsion, nanosuspension and an oil suspension containing were examined with lymph-cannulated anaesthetized rat model. Plasma lymph samples analyzed by HPLC. Lymph triglyceride was measured using enzymatic colorimetric technique. After 8 h, total administered dose accumulated in thoracic duct analyze. Nanoemulsion, 0.065 ± 0.006%, 0.137...
The aim of this study was to quantify the oral delivery systems Tetramethylpyrazine Microemulsion (TMP ME) heart, liver, spleen, lung, kidney and brain by comparing TMP level after administration at a dose 100 mg kg−1 with those tablet suspension SWW). This taken in mice develop suitable analytical methodology pharmacokinetics studies manipulate tissue distribution targeting evaluation. Drug concentrations tissues were determined different times post-mortem. An HPLC method for separation...
To investigate the mechanisms of oil-in-oil nanoemulsions transport through gastrointestinal tract and efficiency changed with its different particle size in lymphatic channels.The behavior vivo their absorption via lymph after oral administration was investigated, pathway clarified by duct cannulation rats.It suggested about 36.8% puerarin transported into systematic circulation lymph. Nanoparticles absorbed channels varied as degree transportion.The is inversely proportional to size.